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INTRODUCTION
LESURIDE contain Levosulpiride which belongs to a group of medicine called gastrointestinal prokinetics. It is indicated for the treatment of different gastrointestinal problems like functional dyspepsia, nausea, vomiting, diabetic gastroparesis, gastroesophageal reflux disease, irritable bowel syndrome.
Gastroesophageal reflux disease is a digestive disease in which stomach acid or bile irritate the food pipe lining which cause burning pain in the chest that usually occur after eating and worsens when lying down. LESURIDE works by increasing the movement of stomach and intestines and prevents reflux (acid going up to the food pipe) and quicken gastric and gall bladder emptying.
During normal digestion, the stomach contract to help break down food and move it into the small intestine. Diabetic gastroparesis disrupts the stomach contraction, which can interrupt digestion. LESURIDE also has gastro kinetic effect and improves glycemic control in diabetic gastroparesis.
LESURIDE will be given to you by a doctor or nurse. It is intended to be administered by IV or IM. Your doctor will decide the dose and frequency depending on your condition. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF LESURIDE
- Treat different gastrointestinal problems like functional dyspepsia, nausea, vomiting, diabetic gastroparesis, gastroesophageal reflux disease, irritable bowel syndrome
HOW LESURIDE WORKS
LESURIDE works by increases the movement of stomach and intestines and prevents reflux (acid going up to the food pipe).
DIRECTIONS FOR USE
LESURIDE will be given to you by a doctor or nurse. It is intended to be administered by IV or IM. Your doctor will decide the dose and frequency depending on your condition.
SIDE EFFECTS OF LESURIDE
SERIOUS
- absence of menstrual periods
- breast enlargement in male
- spontaneous milk secretion
- changes in libido
- neuroleptic malignant syndrome
WARNING & PRECAUTIONS
PREGNANCY
LESURIDE is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
LESURIDE is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machine while taking this medicine as it may cause dizziness or drowsiness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with LESURIDE.
KIDNEY
LESURIDE should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
LESURIDE should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take LESURIDE if you are allergic (hypersensitive) to levosulpiride or any other ingredients in this medicine.
HEART DISEASE
LESURIDE should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you have or had a condition such as,
- hypertension
- epilepsy
- manic state such as in the manic phase of manic-depressive psychosis
- pituitary gland prolactinomas and breast cancer
- cerebrovascular events including risk factor for stroke
- gastrointestinal disorders
- porphyria
- history of neuroendocrine tumor
- pituitary gland prolactinomas and breast cancer
INTERACTIONS
Talk to your doctor if you are taking,
- anticholinergic drugs
- narcotics
- analgesics
- centrally acting drugs
SYNOPSIS
| Drug | : | Levosulpiride |
| Pharmacological Category | : | Gastrointestinal prokinetics |
| Therapeutic Indication | : | Gastrointestinal disorders |
| Dosage Forms | : | Tablet, Capsule, Injection |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT LESURIDE
Is LESURIDE safe?
Yes, it is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Is LESURIDE an antidepressant?
No, it is not an antidepressant. It belongs to a group of medicine called gastrointestinal prokinetics that increase intestinal peristalsis.
Can Levosulpiride be used for gastroesophageal reflux disease and irritable bowel syndrome?
Yes, gastroesophageal reflux disease and irritable bowel syndrome are among the most common reported uses for Levosulpiride. Please do not use this medicine without consulting first with your doctor.
REFERENCES
1. C Mansi 1, V Savarino, S Vigneri, D Perilli, P Melga, L Sciabà, D De Martini, G S Mela. Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Nov 1995. [Accessed 16 Feb 2021] https://pubmed.ncbi.nlm.nih.gov/7485007/
2. Supriyo Choudhury, Koustav Chatterjee, Ravi Singh, Shantanu Shubham, Santosh Trivedi, Suparna Chatterjee,1 and Hrishikesh Kumar. Levosulpiride-induced Movement Disorders. US National Library of Medicines, National Institutes of Health. Oct- Dec 2017. [Accessed 16 Feb 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820749/
3. TORRENT PHARMACEUTICALS LTD; Electronic Medicines Compendium (EMC); [Accessed 16 Feb 2021] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2499.pdf
4. Medindia; [Accessed 16 Feb 2021] https://www.medindia.net/drug-price/levosulpiride/lesuride-inj-25mg.htm
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
Manufacturer/Marketer Details
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