INTRODUCTION

ITRAZEST 1% DUSTING POWDER contains Itraconazole which belongs to the group of medicines called Antifungal agents. It is used to treat fungal infections such as tinea corporis (ring worm of the body), tinea cruris (fungal infection in the skin of the genitals, inner thighs and buttocks), tinea pedis (fungal infection that usually begins between the toes), tinea versicolor (fungal infection that causes small, discoloured skin patches) and onychomycosis (nail infection) in affected individuals. It is also used to sooth irritated skin and provide relief from fungal itch in affected individuals.   

ITRAZEST 1% DUSTING POWDER is not recommended for use in patients who are allergic to itraconazole. ITRAZEST 1% DUSTING POWDER is not recommended for use in pregnant women and it should be used with caution in breast-feeding women only if advised by the doctor.  

The most common side effects associated with the use of ITRAZEST 1% DUSTING POWDER are skin irritation, rashes, burning sensation, redness or itching at the application site. Consult your doctor if any of the side effects worsens.  

USES OF ITRAZEST 1% DUSTING POWDER

• Treat fungal infections such as tinea corporis, tinea cruris, tinea pedis, tinea versicolor (discoloured skin patches) and onychomycosis (nail infection).
• It is also used to sooth irritated skin and provides relief from fungal itch

HOW ITRAZEST 1% DUSTING POWDER WORKS

ITRAZEST 1% DUSTING POWDER works by inhibiting ergosterol synthesis (an organic compound responsible for maintaining cell membrane integrity of fungi cell) that leads to fungal cell membrane abnormalities (marked with increased permeability and disruption of fungi cell) thus causing destruction to the fungi cell and preventing the occurrence of fungal infections in affected individuals.  

DIRECTIONS FOR USE

Use ITRAZEST 1% DUSTING POWDER as advised by your physician. It is for external use only. Clean and wipe to dry the affected area before applying the medicine. Sprinkle enough powder over the infected area. Avoid rubbing it and avoid contact with the eyes, mouth, nose and ears.  

Your doctor will decide the correct dose, frequency and duration of ITRAZEST 1% DUSTING POWDER for you depending upon your age and type or severity of the infection.

SIDE EFFECTS OF ITRAZEST 1% DUSTING POWDER

HOW TO MANAGE SIDE EFFECTS

Skin redness or itching:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoor. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions

Before using ITRAZEST 1% DUSTING POWDER, inform your doctor, if you are taking any of the following medicines:

• rifampicin (used to treat tuberculosis)
• phenytoin, carbamazepine, phenobarbital (used to treat epilepsy)

Overdosage:

If you or anyone else accidentally use too much of ITRAZEST 1% DUSTING POWDER, consult your doctor immediately or visit the nearby hospital. 

SYNOPSIS

MORE INFORMATION

• Keep ITRAZEST 1% DUSTING POWDER out of reach of children
• Store in cool and dry place, protected from moisture

FAQs ABOUT ITRAZEST 1% DUSTING POWDER

What is ITRAZEST 1% DUSTING POWDER used for?

ITRAZEST 1% DUSTING POWDER is used to treat fungal infections such as tinea corporis, tinea cruris, tinea pedis, tinea versicolor (discoloured skin patches), and/or onychomycosis (nail infection) which is also used to sooth irritated skin and provide relief from fungal itch in affected individuals.

What side effects are seen with ITRAZEST 1% DUSTING POWDER?

The most common side effects associated with the use of ITRAZEST 1% DUSTING POWDER are skin irritation, rashes, burning sensation, redness or itching at the application site. Consult your doctor if any of the side effects worsens.

How does ITRAZEST 1% DUSTING POWDER work?

ITRAZEST 1% DUSTING POWDER works by inhibiting ergosterol synthesis (an organic compound responsible for maintaining cell membrane integrity of fungi cell) that leads to fungal cell membrane abnormalities (marked with increased permeability and disruption of fungi cell) thus causing destruction to the fungi cell and preventing the occurrence of fungal infections in affected individuals.

How to use ITRAZEST 1% DUSTING POWDER?

Use ITRAZEST 1% DUSTING POWDER as advised by your physician. It is for external use only. Clean and wipe to dry the affected area before applying the medicine. Sprinkle enough powder over the infected area. Avoid rubbing it and avoid contact with the eyes, mouth, nose and ears.  

Does ITRAZEST 1% DUSTING POWDER cause skin redness or itching?

Yes, it may cause skin redness or itching in some individuals. To manage this effect, avoid taking hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoor. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

REFERENCES

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 794.

2. Heidi Kurn, Roopma Wadhwa. Itraconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. April 2022. [Accessed on 30th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK557874/

3. Bethesda. Itraconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. Drugs and Lactation Database (LactMed) [Internet]. September 2022. [Accessed on 30th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK500573/

4. Antonio De Vuono, Caterina Palleria, Francesca Scicchitano, Aida Squillace, Giovambattista De Sarro, Luca Gallelli. Skin rash during treatment with generic itraconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed Central. June 2014. [Accessed on 30th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008915/

5. Aditya K Gupta, Elizabeth A Cooper, Gabriele Ginter. Efficacy and safety of itraconazole use in children. NIH National Library of Medicine. National Center for Biotechnology Information. July 2003. [Accessed on 30th September 2022] https://pubmed.ncbi.nlm.nih.gov/12956205/

6. QndQ Derma. Iptozol (Powder). [Accessed on 30th September 2022] https://www.qndqdermacare.com/product/Iptozol-Dusting-Powder

7. Nilrise Pharma. Itrazil Dusting Powder. [Accessed on 30th September 2022] https://www.nilrisepharma.com/product/Itrazil-Dusting-powder

8. Eris Oaknet Healthcare. Flucos ITZ Dusting Powder. [Accessed on 30th September 2022] https://oaknethealthcare.com/product/flucos-itz-powder-75g/

USEFUL DIAGNOSTIC TESTS

• Fungal Culture Test