HYALGAN 20mg Injection 2ml

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Drug Information

What is Hyaluronidase used for?

Hyaluronidase injection is used to increase the absorption and distribution of injected fluids and drugs in the body. It is also used for the treatment of dehydration.

Hyaluronidase may also be prescribed for other conditions as determined by the doctor.

How does Hyaluronidase work?

Hyaluronidase is a protein enzyme, which acts by reducing the viscosity between tissues. This helps in increasing the diffusion of injected fluids, thereby facilitating their absorption in the body.

How to administer Hyaluronidase?

The dosage and the drug form depend on the age, weight and medical condition of an individual.

Hyaluronidase should be administered as intravenous injection only under the medical supervision.

If you miss a dose of Hyaluronidase, please consult the doctor immediately.

What are the drugs that interact with Hyaluronidase?

Drugs that interact with Hyaluronidase include the following:

  • Heparin
  • Salicylates
  • Urokinase

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Hyaluronidase?

The following are the most common side effects of Hyaluronidase:

  • Cough
  • Increased palpitations
  • Itching
  • Lethargy
  • Urticaria

The following are the severe side effects and you may require immediate medical attention:

  • Blurry vision
  • Chills
  • Increased heart rate
  • Increased sweating
  • Inflammation of the skin

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while receiving Hyaluronidase?

  • Seek doctor’s advice before taking any other drug or herbal products while on Hyaluronidase medicine.
  • Do not exceed the dose more than what is prescribed.
  • Consult the doctor before taking any other drug along with Hyaluronidase medicine.
  • Avoid using the medicine if you are allergic to Hyaluronidase or similar drugs.
  • Be cautious while receiving Hyaluronidase if you have any kidney or liver impairment.

What should you tell your doctor before receiving Hyaluronidase?

  • Tell your doctor if you have any history of diabetes, hypertension and cardiovascular disorders.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.

Frequently Asked Questions about Hyaluronidase

  1. How should Hyaluronidase be stored?
  2. Store Hyaluronidase intact vials in refrigerator at 2 – 8°C.  Keep the medicine free from contamination.

  3. What are the other formulations of Hyaluronidase available?
  4. Hyaluronidase medicine is available only as injection. However, it is either administered through the intravenous or subcutaneous route.

  5. How long can I administer Hyaluronidase?
  6. Hyaluronidase should be administered till the course is completed. Abrupt discontinuation of the medicine may lead to recurrence of the disease.

  7. Is it safe to alter the dose of Hyaluronidase?
  8. No. Do not alter the dose of Hyaluronidase. Consult your doctor if you have any problem with the dose.

  9. Do I need to be monitored for any laboratory parameters while receiving Hyaluronidase?
  10. You must monitor serum electrolyte levels while receiving Hyaluronidase.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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