INTRODUCTION

HUMINSULIN R 100IU contains human insulin, which is used to treat diabetes. It is used to reduce the high blood sugar level in patients with diabetes mellitus (diabetes). Diabetes is a disease where your body does not produce enough insulin to control the level of your blood sugar. Treatment with this medicine helps to prevent complications from your diabetes.

Human insulin lowers blood glucose by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulins inhibit lipolysis and proteolysis and enhance protein synthesis. Always use your insulin and adjust your dose exactly as your doctor has told you. It is administered by injection under the skin (subcutaneously). You must never inject yourself directly into a vein (intravenously) or muscle (intramuscularly). It can be used in children and adolescents.

Tell your doctor, if you are taking, recently taken or might take any other medicines. The most common side effects of HUMINSULIN R 100IU include low blood sugar (hypoglycemia), allergic reactions including reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, weight gain, and swelling of your hands and feet.

USES OF HUMINSULIN R 100IU

• Reduce the high blood sugar level in patients with diabetes mellitus (diabetes)

HOW HUMINSULIN R 100IU WORKS

Human insulin lowers blood glucose by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulins inhibit lipolysis and proteolysis and enhance protein synthesis.

DIRECTIONS FOR USE

Always use your insulin and adjust your dose exactly as your doctor has told you. It is administered by injection under the skin (subcutaneously). You must never inject yourself directly into a vein (intravenously) or muscle (intramuscularly).

SIDE EFFECTS OF HUMINSULIN R 100IU

HOW TO MANAGE SIDE EFFECTS

Skin itching:

Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used on regular basis to soothe and hydrate the affected area.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking:

• Thiazolidinediones
• new prescription or over-the-counter medicines, vitamins, or herbal supplements

SYNOPSIS

MORE INFORMATION

Store in a refrigerator at 2-8°C and keep out of reach of children. Do not freeze.

FAQs ABOUT HUMINSULIN R 100IU

Can HUMINSULIN R 100IU be used in pregnant women?

Yes. It is considered safe for use by pregnant women. It is advised to consult your doctor before taking this medicine.

How quickly does HUMINSULIN R 100IU work?

It lowers blood glucose by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulins inhibit lipolysis and proteolysis and enhance protein synthesis.

REFERENCES

1. Jean Claude Mbanya, Juergen Sandow, Wolfgang Landgraf and David R Owens; Recombinant Human Insulin in Global Diabetes Management – Focus on Clinical Efficacy, [Published on 2006] [Accessed 17 Dec 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813441/

2. K.D.Tripathi, Essentials of medical pharmacology, Hormones and related drugs, Chapter 19 – Insulin, Oral Hypoglycaemic Drugs and Glucagon, Page – 258, 259, 264.

3. Novo Nordisk A/S, Electronic Medicines Compendium (EMC); [Revised on 09/2020] [Accessed 17 Dec 2020] https://www.medicines.org.uk/emc/files/pil.3848.pdf

4. Eli Lilly and Company Limited, Electronic Medicines Compendium (EMC); [Revised on 06/2020] [Accessed 17 Dec 2020] https://www.medicines.org.uk/emc/files/pil.8196.pdf

5. Lilly USA, LLC, Indianapolis, IN 46285, USA, Eli Lilly and Company Limited, [Revised on 11/2019] [Accessed 17 Dec 2020] https://uspl.lilly.com/humulin7030/humulin7030.html#ppi