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HEALGRAFT S 360 Tablet 10's

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Auto Immune Disease Rx required
Mycophenolate Mofetil 360 mg
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Best Price* ₹ 574.00 MRP ₹ 700.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Rene Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

INTRODUCTION

HEALGRAFT S 360 TABLET contains Mycophenolate mofetil which belongs to the group of medicines called Immunosuppressants. It is used to prevent your body rejecting a transplanted organ (such as kidney, heart, and liver). It is also given with other medications such as corticosteroids and ciclosporin.

Your doctor will perform some regular blood tests to monitor any changes in your body. HEALGRAFT S 360 TABLET may increases the risk of skin cancer. Limit your exposure to sunlight and ultraviolet light by covering the exposed areas of skin as much as possible and by applying sunscreen with a high protective factor.

HEALGRAFT S 360 TABLET can cause birth defects and miscarriage, hence it is strictly not recommended for use in pregnant women and breastfeeding women.

HEALGRAFT S 360 TABLET is not recommended for use in children under 2 years of age. Contact your doctor before taking.

HEALGRAFT S 360 TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking HEALGRAFT S 360 TABLET.

The most common side effects of taking HEALGRAFT S 360 TABLET are nausea, vomiting, diarrhea, stomach pain, headache, high blood pressure, and low number of white blood cells. Contact your doctor if the above side effects worsen.

USES OF HEALGRAFT S 360 TABLET

  • Used to prevent your body rejecting a transplanted organ (such as kidney, heart, and liver)

HOW HEALGRAFT S 360 TABLET WORKS

HEALGRAFT S 360 TABLET belongs to immunosuppressants which reduces the action of the body's own defense system (the immune system) and prevents rejection of the transplanted organ.

DIRECTIONS FOR USE

Take HEALGRAFT S 360 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your dosage will vary depending on the type of transplant you received. Do not stop the medicine suddenly without the concern of your doctor.

SIDE EFFECTS OF HEALGRAFT S 360 TABLET

COMMON

  • decreased white blood cells
  • decrease in calcium levels of blood
  • abnormal potassium levels in the blood (high or low)
  • raised uric acid levels in the blood
  • high or low blood pressure
  • anxiety
  • diarrhoea
  • joint or muscle pain
  • tiredness, shortness of breath and pale skin (decrease in red blood cells)
  • unexpected bleeding and bruising (decrease in blood platelets)
  • hypomagnesemia (decrease in magnesium levels of blood)
  • dizziness
  • headache
  • cough
  • shortness of breath
  • stomach pain, inflammation of the lining of the stomach, abdominal bloating, constipation, indigestion, flatulence, loose stools, nausea, vomiting
  • tiredness
  • fever
  • change in liver and kidney function test results
  • respiratory infection
  • acne
  • weakness
  • swelling of hands, ankles, or feet
  • itching

UNCOMMON

  • fast heartbeat or irregular heartbeat
  • fluid in the lungs  
  • presence of cyst in lymph  
  • trembling, difficulty in sleeping
  • conjunctivitis, blurry vision
  • bad breath, gas formation, intestinal blockage, ulcers on lips, heartburn, discoloration of tongue, dry mouth, inflammation of the gums
  • loss of appetite
  • wheezing
  • blockage of salivary glands
  • elevated lipid levels
  • increase in blood glucose levels or blood cholesterol levels
  • strange dreams, delusions
  • pain, rigors
  • inability to keep an erection
  • cough, difficulty breathing, painful breathing
  • fever, chills, nausea, vomiting, low body temperature, fast heartbeat

RARE

Stop taking HEALGRAFT S 360 TABLET and contact your doctor immediately if you experience any of the following side effects:

  • yellowish discoloration of skin and whites of eyes, nausea, loss of appetite and dark urine
  • persistent cough or become breathlessness
  • signs of infection such as fever, chills, sore throat, sweating, feeling tired, drowsy, or lack of energy
  • blood vomit blood or blood in stools due stomach, or intestinal ulcer
  • swelling of glands, development of a new skin growth or enlargement of an existing skin growth, or changes in an existing mole. may lead to development of cancer of the skin or lymph nodes
  • rashes, swelling of face, lips, tongue or throat causing difficulty breathing

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink plenty of water and fruit juice to keep yourself hydrated. Contact your doctor if the diarrhea did not improve.

Headache:

Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the headache did not improve.

Nausea and Vomiting:

Take the medicine, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if nausea and vomiting did not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if the dizziness did not improve.

Stomach pain:

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if the stomach pain did not improve.

WARNING & PRECAUTIONS

PREGNANCY

HEALGRAFT S 360 TABLET is not recommended for use in pregnant women. Inform your doctor if you are planning to have a child before taking this medicine. Contact your doctor before taking HEALGRAFT S 360 TABLET.

BREASTFEEDING

HEALGRAFT S 360 TABLET is generally not recommended for use in breastfeeding women, hence small amounts of the medicine can pass into the mother’s milk. Contact your doctor before taking HEALGRAFT S 360 TABLET.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel drowsiness, somnolence, dizziness, tremor, low blood pressure, numb or confusion after taking HEALGRAFT S 360 TABLET.

KIDNEY

HEALGRAFT S 360 TABLET should be used with caution in patients with kidney diseases. Contact your doctor before taking HEALGRAFT S 360 TABLET.

LIVER

HEALGRAFT S 360 TABLET should be used with caution in patients with liver diseases. Contact your doctor before taking HEALGRAFT S 360 TABLET.

ALLERGY

Do not take HEALGRAFT S 360 TABLET if you are allergic (hypersensitive) to Mycophenolate mofetil, or to some sugars such as lactose, galactose, or glucose or to other ingredients of this medicine.

LUNGS

HEALGRAFT S 360 TABLET should be used with caution in patients with lung diseases. Contact your doctor before taking HEALGRAFT S 360 TABLET.

HEART DISEASE

HEALGRAFT S 360 TABLET should be used with caution in patients with heart diseases. Contact your doctor before taking HEALGRAFT S 360 TABLET.

OTHERS

HEALGRAFT S 360 TABLET is not recommended for use if you:

  • have hereditary enzyme deficiency such as Lesch-Nyhan (neurogenetic disorder) and Kelley-Seegmiller syndrome (partial deficiency of the enzyme hypoxanthine guanine phosphoribosyl transferase)

Before taking HEALGRAFT S 360 TABLET, inform your doctor if you:

  • have any unexpected bruising (skin discoloration from a skin or tissue injury) or bleeding
  • have digestive problems (such as a stomach ulcer)
  • have a rare problem with your metabolism called phenylketonuria (hereditary condition that results in an accumulation of the phenylalanine)
  • are planning to get live vaccinations
  • have Hepatitis B or C infections
  • have skin cancer or lymphoma

Use in pediatrics:

HEALGRAFT S 360 TABLET is not recommended for use in children under the age of 2, because there is limited information on its safety and effectiveness. Contact your doctor before taking HEALGRAFT S 360 TABLET.

Use in geriatrics:

HEALGRAFT S 360 TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking HEALGRAFT S 360 TABLET.

INTERACTIONS

A. Drug-Drug interactions:

Before taking HEALGRAFT S 360 TABLET, inform your doctor if you are taking any of the following medicine:

  • azathioprine, tacrolimus, belatacept, cyclosporine A (suppress your immune system given after a transplant operation)
  • cholestyramine (medicine used to treat high cholesterol)
  • rifampicin (medicines used to prevent and treat infections such as TB)
  • medicines used to treat ulcer problems (antacids such as aluminium hydroxide, magnesium hydroxide, sodium bicarbonate, calcium carbonate or proton pump inhibitors such as omeprazole, rabeprazole, pantoprazole)
  • phosphate binders (used to reduce phosphate absorption into the blood is used by patients with chronic renal failure) such as ferric citrate, calcium acetate, sevelamer
  • antibiotics (medicines used to treat bacterial infections) amoxicillin and clavulanic acid, doxycycline, ciprofloxacin, clindamycin, metronidazole, azithromycin, trimethoprim/sulfamethoxazole, amikacin, cefadroxil, norfloxacin
  • isavuconazole (medicine used to treat fungal infections)
  • telmisartan (medicine used to treat high blood pressure)
  • activated charcoal (used to treat digestive problems)
  • acyclovir or ganciclovir (medicines used to treat viral infections)
  • oral contraceptives such as Ex. ethinylestradiol and levonorgestrel (medicines used to prevent pregnancy)
  • probenecid (medicines used to treat gout)
  • iron salts such as Ex. ferrous sulphate (medicines used to treat iron deficiency)

Overdosage:

If you or anyone else accidentally takes too much of HEALGRAFT S 360 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms include nausea, vomiting, diarrhea, and neutropenia.

SYNOPSIS

Drug :   Mycophenolate mofetil
Pharmacological Category :   Immunosuppressants
Therapeutic Indication :   Prevents your body from rejecting a transplanted organ                       
Dosage Forms :   Tablet, Capsule, Suspension, Oral suspension

MORE INFORMATION

  • Keep HEALGRAFT S 360 TABLET out of the sight and reach of children
  • Store HEALGRAFT S 360 TABLET below 30°C

FAQs ABOUT HEALGRAFT S 360 TABLET

What is HEALGRAFT S 360 TABLET used for?

HEALGRAFT S 360 TABLET is used to prevent your body from rejecting an organ transplant (such as kidney, heart, and liver). Contact your doctor before taking HEALGRAFT S 360 TABLET.

Can I use HEALGRAFT S 360 TABLET in pregnancy?

No. HEALGRAFT S 360 TABLET is strictly not recommended for use in pregnant women unless considered necessary. Contact your doctor before taking HEALGRAFT S 360 TABLET.

Is HEALGRAFT S 360 TABLET safe?

Yes, HEALGRAFT S 360 TABLET is safe and well tolerated. Contact your doctor before taking.

Can I use HEALGRAFT S 360 TABLET in children?

No, HEALGRAFT S 360 TABLET is not recommended for use in children under the age of 2, because there is limited information on its safety and effectiveness for them. Contact your doctor before taking.

How HEALGRAFT S 360 TABLET work?

HEALGRAFT S 360 TABLET belongs to immunosuppressants which reduces the action of the body's own defense system (the immune system) and prevents rejection of the transplanted organ.

Can I use HEALGRAFT S 360 TABLET while breast feeding?

No. HEALGRAFT S 360 TABLET is generally not recommended for use in breastfeeding women, small amounts of the medicine can pass into the mother’s milk. Contact your doctor before taking it.

REFERENCES

1. KD Tripathi. Immunosuppressant Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 883.

2. Jeffrey J Swigris, Amy L Olson, Aryeh Fischer, David A Lynch, Gregory P Cosgrove, Stephen K Frankel, Richard T Meehan, Kevin K Brown. Uses of Mycophenolate mofetil. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. 2006. [Accessed on 16th July 2022] https://pubmed.ncbi.nlm.nih.gov/16840379/

3. Novartis Pharma GmbH. Electronic Medicines Compendium (EMC); [Revised on July 2021] [Accessed 16th July 2022] https://www.medicines.org.uk/emc/files/pil.5560.pdf

4. Roche Products Limited. Electronic Medicines Compendium (EMC); [Revised on January 2022] [Accessed 16th July 2022] https://www.medicines.org.uk/emc/files/pil.1102.pdf

5. Novartis Pharma GmbH. Electronic Medicines Compendium (EMC); [Revised on July 2021] [Accessed 16th July 2022] https://www.medicines.org.uk/emc/files/pil.7793.pdf

6. Accord Healthcare B.V. Electronic Medicines Compendium (EMC); [Revised on Oct 2020] [Accessed 16th July 2022] https://www.medicines.org.uk/emc/files/pil.5989.pdf

7. Roche Pharma AG. European Medical Agency. [Revised in Jan 2021] [Accessed on 16th July 2022] https://www.ema.europa.eu/en/documents/product-information/cellcept-epar-product-information_en.pdf

8. Biocon. Mycophenolate mofetil. [Accessed on 16th July 2022] https://www.biocon.com/docs/prescribing_information/nephrology/renodapts540_pi.pd

9. Hoffmann-La Roche Limited. Mycophenolate mofetil. [Revised on January 2022] [Accessed 16th July 2022] https://www.rochecanada.com/PMs/CellCept/CellCept_PM_E.pdf

10. Mycophenolate mofetil. Mims.com. [Accessed on 16th July 2022] https://www.mims.com/india/drug/info/mycophenolic%20acid?type=full&mtype=generic

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function test
  • Kidney function test

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 12 Nov 2022 | 12:00 AM(IST)

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    MYCOPHENOLATE MOFETIL 360MG
    Hsn Code
    30049099
ALTERNATE BRANDS
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.