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INTRODUCTION
GRILINCTUS BM SYRUP is a combination of Bromhexine and Terbutaline which belongs to the group of medicines called Mucolytics and Bronchodilator respectively. GRILINCTUS BM SYRUP is used in the management of productive cough associated with bronchial asthma, acute and chronic bronchitis and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist.
Before taking GRILINCTUS BM SYRUP, inform your doctor if you have or have ever had a stomach ulcer or if you are taking any other medicines like antibiotics. GRILINCTUS BM SYRUP should be used with caution in pregnant women, breastfeeding women, and elderly. Consult your doctor for advice.
GRILINCTUS BM SYRUP is recommended only in children above 2 years of age. The common side effects of GRILINCTUS BM SYRUP feeling sick (nausea) or being sick (vomiting), pain in the upper part of your abdomen, diarrhoea. Consult your doctor immediately if you feel any of these side effects worsen or persists for a longer duration.
USES OF GRILINCTUS BM SYRUP
Used in the management of productive cough associated with:
- bronchial asthma
- acute and chronic bronchitis
- other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist
HOW GRILINCTUS BM SYRUP WORKS
GRILINCTUS BM SYRUP is a combination of Bromhexine and Terbutaline medicine. Bromhexine is a mucolytic (agents that break down mucus present making it loose and thin) that it easier to cough out. Terbutaline is a bronchodilator which relaxes muscles in the airways, widens the airways and eases the symptoms.
DIRECTIONS FOR USE
Take GRILINCTUS BM SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF GRILINCTUS BM SYRUP
COMMON
- nausea, vomiting
- pain in the upper part of abdomen
- diarrhoea
RARE
- hypersensitivity reactions
- rash, urticaria (itching)
- tremors
- headache
- palpitation
- rapid heart rate
- shortness of breath
- flushed feeling and sweating
- anxiety
- muscle cramps
- dry mouth
Stop taking GRILINCTUS BM SYRUP and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reactions that may cause swelling of face or throat, wheezing or sudden difficulties in breathing
- skin lesions such as severe blistering or peeling of your skin, mouth, throat, nose, eyes and genitals
- uncontrollable shaking
- nervousness
- dizziness, drowsiness
- difficulty falling asleep or staying asleep
- weakness
- sweating
- feel tightness of your chest
- signs of pruritus
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Nausea And Vomiting
Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredGRILINCTUS BM SYRUP is not recommended during pregnancy unless it is deemed necessary. Consult your doctor for advice.
BREASTFEEDING
Monitoring requiredGRILINCTUS BM SYRUP is not recommended during breast feeding unless it is deemed necessary. Consult your doctor for advice.
DRIVING AND USING MACHINES
Use with CautionGRILINCTUS BM SYRUP does not influence the capacity of driving or operating any machines.
ALLERGY
ContraindicatedDo not take GRILINCTUS BM SYRUP if you are allergic to Bromhexine or Terbutaline or any other ingredients of this medicine.
HEART DISEASE
Use with CautionGRILINCTUS BM SYRUP should be used with caution in patients with heart diseases. Consult your doctor for advice.
USE IN PEDIATRICS
ContraindicatedGRILINCTUS BM SYRUP is not recommended in children below 2 years of age. Consult your doctor for advice.
USE IN GERIATRICS
Use with CautionGRILINCTUS BM SYRUP should be used with caution in elderly patients. Consult your doctor for advice.
OTHERS
Before taking GRILINCTUS BM SYRUP, inform your doctor if you:
- have intolerance to fructose
- are suffering from fits or have a history of fits
- are suffering from peptic ulcers
INTERACTIONS
A. Drug-Drug interactions:
Before taking GRILINCTUS BM SYRUP, inform your doctor if you are taking any of the following medicine:
- antibiotics used to treat infections. (Ex. ampicillin, amoxicillin, erythromycin or oxytetracycline)
Overdosage:
If you or anyone else accidentally takes too much of GRILINCTUS BM SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are abdominal pain, agitation, palpitations (being of your heartbeat), seizures/fits, hypertension, hypotension (fainting) tachycardia (increased heartbeat) nervousness, headache, tremor, dry mouth, nausea, dizziness, fatigue, malaise (weakness) and insomnia (sleeplessness).
SYNOPSIS
| Drug | : | Bromhexine, Terbutaline |
| Pharmacological Category | : | Mucolytic, Beta-adrenergic agonist |
| Therapeutic Indication | : | Treats cough |
| Dosage Forms | : | Syrup |
MORE INFORMATION
- Keep GRILINCTUS BM SYRUP out of reach of children
- Store at room temperature
FAQs ABOUT GRILINCTUS BM SYRUP
Q: What is GRILINCTUS BM SYRUP used for?
A: GRILINCTUS BM SYRUP is used to relieve cough associated with bronchitis, bronchial asthma, emphysema, and other broncho-pulmonary disorders.
Q: How is GRILINCTUS BM SYRUP useful in treating severe cough?
A: GRILINCTUS BM SYRUP is a combination of Bromhexine and Terbutaline. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Terbutaline is a bronchodilator which relaxes muscles in the airways, widens the airways and eases the symptoms. This collective action is useful in relief of cough and discomfort.
Q: How to use GRILINCTUS BM SYRUP?
A: Take GRILINCTUS BM SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q: What are the serious side effects are seen with GRILINCTUS BM SYRUP?
A: Serious allergic reactions that may cause swelling of face or throat, wheezing or sudden difficulties in breathing, skin lesions such as severe blistering or peeling of your skin, mouth, throat, nose, eyes and genitals, uncontrollable shaking, nervousness, dizziness, drowsiness, difficulty falling asleep or staying asleep, weakness and sweating. Consult your doctor for advice.
Q: Will GRILINCTUS BM SYRUP be more effective if taken in more than recommended doses?
A: No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, consult your doctor for re-evaluation.
Q: Can we use GRILINCTUS BM SYRUP for pregnant women?
A: GRILINCTUS BM SYRUP is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
REFERENCES
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Chapter 16 Essentials of medical pharmacology. Seventh edition. 2017.
2. Zanasi, A., Mazzolini, M. & Kantar, A. A reappraisal of the mucoactive activity and clinical efficacy of bromhexine.Springer.com March 2017. [Accessed on 25th June 2022] https://link.springer.com/article/10.1186/s40248-017-0088-1#Sec11
3. Ireland Opella Healthcare. Bromhexine and Terbutaline. [Accessed on 25th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/4550f813-c219-4e0a-b51a-5e6ed8a8e9f0.pdf
4. Rxlist Bromhexine and Terbutaline. [Revised in March 2021] [Accessed on 25th June 2022] https://www.rxlist.com/terbutaline-sulfate-drug.htm
5. The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. Pubmed. [Revised on March 2005] [Accessed on 25th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/terbutaline#section=MeSH-Pharmacological-Classification
6. Franco-Indian. GRILINCTUS–BM. Syrup. [Accessed on 25th June 2022] http://www.francoindian.com/products/grilinctus-bm.htm
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