Glucored Forte Tablet 10'S

Introduction About GLUCORED FORTE TABLET

Glucored Forte Tablet is a combination of Glibenclamide and Metformin, belonging to the class of antidiabetic agents. It is prescribed for adults with type 2 diabetes mellitus to help manage and maintain stable blood glucose levels. This dual-action formulation works by improving the body’s insulin response and reducing excess sugar production in the liver, helping maintain better control of blood sugar throughout the day.

Take Glucored Forte Tablet with food, preferably at the same time each day, for optimal results. Your healthcare provider will determine the appropriate dosage based on your blood sugar readings and overall health condition. Continue using it regularly, even if your blood sugar levels are stable, unless advised otherwise by your doctor.

Discontinuing the tablet without medical advice can lead to elevated blood sugar levels, which may increase the risk of nerve damage, kidney complications, vision problems, or circulatory issues.

For best results, combine this medication with a balanced diet, regular physical activity, and weight management, as recommended by your healthcare professional. A healthy lifestyle plays a crucial role in maintaining effective diabetes control and overall well-being.

The most common effect associated with Glucored Forte Tablet is low blood sugar levels (hypoglycemia). It’s important to identify early signs such as sweating, dizziness, headache, shaking, or feeling weak, and take quick action to restore normal glucose levels. Always keep a fast-acting carbohydrate source like sugar candy, glucose tablets, or fruit juice on hand to manage sudden drops in blood sugar.

Maintaining regular meals and not skipping food can help support stable blood glucose levels while using this tablet. Alcohol consumption can further lower blood sugar and should ideally be avoided during this medication.

Other commonly observed effects may include nausea, vomiting, stomach discomfort, diarrhoea, headache, dizziness, altered taste, weight gain, and respiratory infections. Some individuals may notice a gradual increase in weight while using this medicine.

Glucored Forte Tablet is not recommended for individuals with type 1 diabetes mellitus, diabetic ketoacidosis (a condition marked by high acid levels in the blood), or those with severe kidney or liver complications. Before beginning this medication, inform your healthcare provider if you have a history of heart-related conditions, as the tablet may not be suitable in such cases.

Women who are pregnant, planning to conceive, or breastfeeding should seek medical guidance before using Glucored Forte Tablet to ensure safety for both mother and baby.

Regular monitoring of blood glucose levels is essential while on this medicine. Your doctor may also recommend routine blood tests to evaluate liver function, kidney health, and blood cell counts to ensure the medicine is working safely and effectively.

Uses Of GLUCORED FORTE TABLET

• Helps in the management of type 2 diabetes mellitus in adults.
• Supports control of elevated blood glucose levels when diet and exercise alone are insufficient.
• Aids in enhancing insulin sensitivity and improving glucose utilization by the body.
• Helps reduce excess sugar production in the liver for better blood sugar balance.
• Recommended for individuals requiring dual therapy with Glibenclamide and Metformin for effective glycemic management.
• Assists in maintaining stable day-to-day blood glucose levels to support overall metabolic health.

Benefits of GLUCORED FORTE TABLET

01)Supports Stable Blood Sugar Levels: Helps maintain consistent glucose levels throughout the day in adults with type 2 diabetes mellitus.

02)Enhances Insulin Effectiveness: Improves the body’s insulin response, aiding in better utilization of glucose for energy.

03)Reduces Excess Sugar Production: Helps lower hepatic glucose output, contributing to more balanced blood sugar control.

04)Dual-Action Glycemic Support: Combines Glibenclamide and Metformin for a comprehensive approach to managing blood sugar fluctuations.

05)Promotes Long-Term Glucose Management: Assists in maintaining day-to-day glycemic stability, supporting overall metabolic health.

06)Supports Lifestyle-Based Diabetes Management: Works effectively alongside diet, exercise, and weight management to help optimize blood sugar control.

How GLUCORED FORTE TABLET Works

How Does Glucored Forte Tablet Work?

Glucored Forte Tablet works through a dual mechanism that helps maintain stable blood glucose levels in adults with type 2 diabetes mellitus. Its combination of Glibenclamide and Metformin targets both insulin secretion and glucose production for optimal glycemic management.

Dual Mechanism of Glibenclamide and Metformin

Glucored Forte provides a dual-action approach:

• Glibenclamide enhances insulin release from the pancreas.
• Metformin improves insulin sensitivity and reduces glucose production in the liver.
  This combination ensures better blood sugar regulation and supports overall metabolic health.

Role of Glibenclamide in Blood Sugar Support

Glibenclamide helps the body release insulin effectively, which aids in lowering post-meal blood sugar spikes. By improving insulin availability, it supports consistent blood glucose levels throughout the day.

How Metformin Affects Glucose Metabolism

Metformin primarily reduces hepatic glucose production and enhances glucose uptake in muscles, helping the body use sugar efficiently. This action contributes to steady blood sugar levels and supports long-term glycemic balance.

Insights into Glucored Forte's Glucose Regulation

The combined action of Glibenclamide and Metformin helps regulate blood sugar fluctuations, minimizing highs and lows. This stable glucose control is crucial for controlling diabetes complications and maintaining overall health.

Understanding Insulin Release and Glucose Uptake

Glibenclamide stimulates the pancreas to release insulin, while Metformin increases glucose uptake by cells. Together, this ensures sugar is efficiently absorbed and utilized for energy rather than accumulating in the blood.

Impact on Liver Glucose Production and Intestines

Metformin suppresses excess glucose production in the liver and slightly reduces sugar absorption in the intestines, providing a dual benefit for maintaining balanced blood sugar levels.

Benefits of Combined Action for Blood Sugar Balance

The synergy of Glibenclamide and Metformin in Glucored Forte ensures effective daily blood sugar management, reduces fluctuations, and supports long-term metabolic health. Regular use alongside diet and exercise helps optimize type 2 diabetes care.

How to use GLUCORED FORTE TABLET

How to Use Glucored Forte Tablet Safely

• Glucored Forte Tablet should be taken under the supervision of a healthcare professional.
• Always follow your doctor’s instructions and maintain regular blood sugar monitoring to ensure safe and effective use.
• Avoid self-adjusting the dose without medical advice, as it may lead to blood sugar fluctuations or hypoglycemia.

Recommended Dosage of Glucored Forte Tablet

• The dosage of Glucored Forte Tablet is determined by your healthcare provider based on your blood sugar levels, medical history, and response to management.
• It is typically taken once or twice daily, but your doctor will adjust the dose to maintain optimal glucose control.

When and How to Take Glucored Forte Tablet

• For best results, take Glucored Forte Tablet with meals, usually morning and/or evening as prescribed.
• Taking it with food helps reduce stomach upset and supports steady blood sugar levels throughout the day.
• Stick to a consistent schedule to maximize effectiveness.

Important Tips for Taking Glucored Forte Tablet

• Maintain a balanced diet and regular exercise while using the tablet.
• Avoid skipping meals to control low blood sugar (hypoglycemia).
• Monitor your blood sugar regularly to track progress.
• Limit alcohol consumption, as it can increase the risk of hypoglycemia.
• Keep a fast-acting carbohydrate source (like glucose tablets or juice) handy for emergencies.

What if I forgot to take GLUCORED FORTE TABLET

If you miss a dose of Glucored Forte Tablet, take it as soon as you remember with your next meal. Do not double the dose to make up for a missed one, as this can lead to low blood sugar levels. Consistency in your dosing schedule is important for maintaining stable glucose control.

Side Effects Of GLUCORED FORTE TABLET

Common:

• Nausea
• Vomiting
• Stomach discomfort
• Diarrhoea
• Headache
• Dizziness
• Altered taste
• Weight gain
• Respiratory infections
• Low blood sugar levels (hypoglycemia) signs such as sweating, dizziness, headache, shaking, or feeling weak

When to consult your doctor?

• Severe Hypoglycemia (Low Blood Sugar) symptoms include confusion, sweating, rapid heartbeat, dizziness, shaking, blurred vision, or fainting.
• Allergic Reactions Signs include rash, itching, swelling of face or throat, severe dizziness, or difficulty breathing.
• Liver Problems symptoms such as yellowing of eyes or skin (jaundice), dark urine, persistent nausea or vomiting, or abdominal pain.
• Severe Gastrointestinal Reactions symptoms such as vomiting, diarrhoea, or stomach pain
• Signs of Lactic Acidosis such as unusual tiredness, muscle pain, breathing difficulties, cold or blue extremities, or slow/irregular heartbeat.
• Fluid retention or heart complications symptoms such as swelling or rapid weight gain.

How To Manage Side Effects

Diarrhea

• Stay Hydrated: Drink plenty of fluids such as water, oral rehydration solutions (ORS), or clear broths to control dehydration.
• Eat Light and Easy-to-Digest Foods: Consume bland foods like rice, bananas, toast, and applesauce while avoiding spicy, fatty, or heavy meals.
• Avoid Irritants: Limit caffeine, alcohol, and dairy products if they worsen symptoms.
• Rest and Maintain Hygiene: Get adequate rest and wash hands frequently to reduce the risk of infection spreading.
• Seek Medical Advice: Contact your healthcare provider if diarrhoea is severe, persistent, contains blood, or is accompanied by fever, dehydration, or other concerning symptoms.

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to reduce falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

• Stay Hydrated: Drink plenty of water throughout the day to help ease headache symptoms.
• Rest in a Quiet Environment: Minimize noise and bright lights by resting in a calm, dark room.
• Use Over-the-Counter Pain Relief: Consult your doctor about using mild pain relievers like acetaminophen to alleviate headaches.
• Avoid Stressful Activities: Limit activities that increase stress or physical exertion when experiencing headaches.
• Seek Medical Advice: Contact your healthcare provider if headaches become severe, persistent, or are accompanied by other symptoms.

Nausea And Vomiting

• Stay Hydrated: Sip fluids slowly, such as water, ginger tea, or clear soups to support hydration and reduce discomfort.
• Eat Small, Bland Meals: Choose light foods like crackers, toast, or plain rice to minimize stomach irritation.
• Avoid Strong Odors and Spicy Foods: These can worsen feelings of nausea and should be limited during symptoms.
• Rest and Relaxation: Rest in a comfortable position and avoid sudden movements to calm the digestive system.
• Seek Medical Advice: Consult a healthcare provider promptly if nausea is severe, persistent, or accompanied by vomiting.

Warning & Precautions

Pregnancy

Contraindicated

GLUCORED FORTE TABLET is generally not recommended for use in pregnant women due to lack of safety data. However, consult your doctor for advice before using GLUCORED FORTE during pregnancy.

Breastfeeding

Contraindicated

GLUCORED FORTE TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. However, consult your doctor for advice before taking GLUCORED FORTE while breastfeeding.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy after taking GLUCORED FORTE TABLET. Drowsiness or dizziness may impair your ability to perform tasks safely.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking GLUCORED FORTE TABLET as it may increase your blood sugar levels and heighten the risk of side effects associated with GLUCORED FORTE.

Kidney

Consult your doctor

GLUCORED FORTE TABLET is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with mild to moderate kidney problems. Therefore, consult your doctor for advice before taking GLUCORED FORTE if you have kidney-related issues.

Liver

Consult your doctor

GLUCORED FORTE TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor for advice before using GLUCORED FORTE if you have any liver condition.

Allergy

Contraindicated

Do not take GLUCORED FORTE TABLET if you are allergic to Glibenclamide or Metformin, or any other component of GLUCORED FORTE.

Heart Disease

Contraindicated

GLUCORED FORTE TABLET is not recommended for use in patients with severe heart problems (such as heart failure, recent heart attack, stroke, or other circulation problems). Therefore, consult your doctor for advice before starting GLUCORED FORTE if you have any heart-related condition.

Use In Pediatrics

Contraindicated

GLUCORED FORTE TABLET is generally not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor for advice before giving GLUCORED FORTE to children.

Use In Geriatrics

Use with Caution

GLUCORED FORTE TABLET should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor for advice before using GLUCORED FORTE in older adults.

Other Warnings for GLUCORED FORTE TABLET

Before taking GLUCORED FORTE TABLET, inform your doctor if you:

• Are scheduled for any X-ray
• Are scheduled for any upcoming surgeries
• Have hormonal imbalance (Ex. thyroid problems)
• Have problems in adrenal cortex or pituitary gland (Ex. Hyperaldosteronism, Cushing’s syndrome)
• Are malnourished, starved, on an irregular diet, or feeling weak
• Have G6PD deficiency (a genetic disorder that affects red blood cells in the body)

Who should not take GLUCORED FORTE TABLET

GLUCORED FORTE TABLET is not recommended for use if you:

• Have uncontrollable diabetes
• Have type I diabetes mellitus
• Are severely dehydrated (due to excessive vomiting, diarrhoea, sweating, increased physical activity or if you drink less quantity of fluids)
• Have severe systemic infections affecting your lungs or kidneys
• Have diabetic ketoacidosis (increased levels of ketone bodies in the blood)

Diet and Lifestyle Advice

What Are the Best Diet and Lifestyle Tips to Follow While Taking GLUCORED FORTE Tablet for Effective Blood Sugar Management?

Drug - Drug interaction

Before taking GLUCORED FORTE TABLET, inform your doctor if you are taking any of the following medicines such as:

1. Blood Thinners (e.g., Warfarin, Aspirin)

Interaction: Using GLUCORED FORTE TABLET with blood thinners may increase the risk of bleeding.
Effects: Symptoms can include unusual bruising, bleeding gums, nosebleeds, or blood in urine or stools.
Management: Inform your doctor if you notice any signs of bleeding. Your doctor may adjust medication doses or monitor your blood clotting levels closely while you are taking GLUCORED FORTE.

2. Beta-Blockers (e.g., Propranolol, Atenolol, Metoprolol)

Interaction: Beta-blockers can mask symptoms of low blood sugar (hypoglycemia) caused by GLUCORED FORTE TABLET.
Effects: Signs such as tremors, rapid heartbeat, or sweating may not be easily noticed.
Management: Regularly monitor blood glucose levels and inform your doctor if you experience confusion or dizziness while taking GLUCORED FORTE with beta-blockers.

3. Corticosteroids (e.g., Prednisone, Hydrocortisone)

Interaction: Corticosteroids can reduce the blood sugar–lowering effect of GLUCORED FORTE TABLET.
Effects: May cause increased blood glucose levels, leading to reduced medicine effectiveness.
Management: Regularly check your blood sugar levels and consult your doctor if they remain high. Dose adjustments to GLUCORED FORTE or corticosteroids may be needed.

4. Diuretics (Water Pills) (e.g., Furosemide, Hydrochlorothiazide)

Interaction: Diuretics can alter glucose metabolism and increase the risk of dehydration, especially when combined with GLUCORED FORTE TABLET.
Effects: Symptoms include thirst, weakness, or dry mouth.
Management: Stay well-hydrated and inform your doctor if dehydration symptoms persist while using GLUCORED FORTE with diuretics.

5. Thyroid Medications (e.g., Levothyroxine)

Interaction: Thyroid hormones can reduce the effectiveness of GLUCORED FORTE TABLET in controlling blood sugar.
Effects: May lead to elevated blood glucose levels despite regular medication use.
Management: Frequent blood sugar monitoring and possible dose adjustments may be necessary when GLUCORED FORTE is used alongside thyroid therapy.

6. Antifungal and Antibiotic Medicines (e.g., Fluconazole, Rifampicin)

Interaction: Certain antifungals and antibiotics may increase or decrease the blood levels of GLUCORED FORTE TABLET, affecting its action.
Effects: May cause hypoglycemia (low blood sugar) or reduced glucose control.
Management: Your doctor may monitor your blood sugar more closely or modify doses while using GLUCORED FORTE with these medicines.

Drug - Food interaction

1. High-Sugar Foods and Beverages (e.g., Sweets, Soft Drinks)

Interaction: Consuming sugary foods or drinks while taking GLUCORED FORTE TABLET can raise blood sugar levels and reduce the medicine’s effectiveness.
Effects: May cause high blood glucose (hyperglycemia), fatigue, or increased thirst.
Management: Limit or avoid sugary foods, desserts, and sweetened drinks. Follow a low-sugar, balanced diet to help GLUCORED FORTE work effectively.

2. Alcohol (Ethanol)

Interaction: Alcohol can enhance the blood sugar–lowering effect of GLUCORED FORTE TABLET and increase the risk of hypoglycemia or lactic acidosis.
Effects: Symptoms include dizziness, sweating, irregular heartbeat, or weakness.
Management: Avoid alcohol consumption while using GLUCORED FORTE. If unavoidable, drink only in moderation and always with food.

3. High-Fat Meals

Interaction: Eating large amounts of fatty foods may delay the absorption of GLUCORED FORTE TABLET, reducing its efficiency in maintaining steady glucose levels.
Effects: May lead to fluctuations in blood sugar or delayed glucose control.
Management: Choose low-fat, nutrient-dense meals and take GLUCORED FORTE with balanced food portions for consistent results.

4. Caffeine-Containing Drinks (e.g., Coffee, Energy Drinks)

Interaction: Excess caffeine can affect glucose metabolism and interfere with the blood sugar–lowering action of GLUCORED FORTE TABLET.
Effects: May cause rapid heartbeat, nervousness, or sudden changes in glucose levels.
Management: Limit caffeine intake and monitor blood sugar regularly while taking GLUCORED FORTE.

5. Fiber-Rich Foods (e.g., Whole Grains, Vegetables, Legumes)

Interaction: A very high intake of dietary fiber may slow down the absorption of GLUCORED FORTE TABLET, slightly affecting its blood sugar–controlling ability.
Effects: May lead to delayed onset of medicine action.
Management: Maintain a balanced fiber intake and avoid excessive consumption immediately around GLUCORED FORTE dosing times.

6. Grapefruit and Grapefruit Juice

Interaction: Grapefruit can alter the metabolism of certain medicines, including GLUCORED FORTE TABLET, and affect blood sugar control.
Effects: May cause unpredictable glucose levels or increase side effect risks.
Management: Avoid grapefruit or its juice unless your doctor confirms it is safe with GLUCORED FORTE.

7. Skipping Meals

Interaction: Missing meals while taking GLUCORED FORTE TABLET can lead to low blood sugar (hypoglycemia).
Effects: Symptoms include sweating, shaking, confusion, dizziness, or fainting.
Management: Always take GLUCORED FORTE with food and maintain regular meal timings to control hypoglycemia.

Synopsis

More Information

FAQs About GLUCORED FORTE TABLET

Q: What is GLUCORED FORTE TABLET used for?

A: GLUCORED FORTE TABLET is used to help manage blood sugar levels in adults with type 2 diabetes mellitus. It combines Glibenclamide and Metformin, which work together to improve insulin response, reduce sugar production in the liver, and maintain steady glucose levels throughout the day.

Q: How does GLUCORED FORTE TABLET work in the body?

A: GLUCORED FORTE TABLET works through a dual mechanism. Glibenclamide increases insulin release from the pancreas, while Metformin decreases glucose production in the liver and improves insulin sensitivity. Together, they help maintain balanced blood sugar levels.

Q: When should I take GLUCORED FORTE TABLET?

A: GLUCORED FORTE TABLET should be taken with meals, usually once or twice daily, as prescribed by your doctor. Taking it with food helps reduce stomach upset and minimizes the risk of low blood sugar.

Q: What are the common side effects of GLUCORED FORTE TABLET?

A: Common side effects may include nausea, vomiting, diarrhoea, stomach discomfort, dizziness, headache, or mild weight gain. Low blood sugar (hypoglycemia) can also occur, especially if meals are skipped or delayed.

Q: Can I take GLUCORED FORTE TABLET during pregnancy or breastfeeding?

A: GLUCORED FORTE TABLET is generally not recommended during pregnancy or breastfeeding due to limited safety data. Always consult your doctor for personalized advice before using this medicine in such conditions.

Q: Can I drink alcohol while taking GLUCORED FORTE TABLET?

A: It is advised to avoid alcohol while taking GLUCORED FORTE TABLET, as it can increase the risk of low blood sugar (hypoglycemia) or a rare but serious condition called lactic acidosis.

Q: What should I do if I miss a dose of GLUCORED FORTE TABLET?

A: If you miss a dose, take it with your next meal as soon as you remember. Do not take two doses together to make up for the missed one. Continue with your regular dosing schedule.

Q: Can GLUCORED FORTE TABLET be taken with other diabetes medicines?

A: GLUCORED FORTE TABLET may be taken with other antidiabetic medicines if prescribed by your doctor. However, combining medications increases the risk of hypoglycemia, so blood sugar levels should be monitored closely.

Q: What precautions should I follow while using GLUCORED FORTE TABLET?

A: Inform your doctor if you have kidney, liver, or heart problems before taking GLUCORED FORTE TABLET. Maintain a healthy diet, exercise regularly, and monitor your blood sugar as advised by your healthcare provider.

Q: How long does it take for GLUCORED FORTE TABLET to show results?

A: GLUCORED FORTE TABLET starts working within a few days of regular use, but noticeable improvement in blood sugar control may take a few weeks. Consistent use, healthy eating, and regular exercise help achieve the best results.

Q: Are there any dietary considerations to follow while using GLUCORED FORTE TABLET?

A: Yes, when using GLUCORED FORTE TABLET, it is important to follow a balanced diet to support blood sugar control. Include whole grains, fresh vegetables, lean proteins, and fiber-rich foods in your meals. Avoid refined sugars, fried foods, processed snacks, and sweetened beverages. Eating small, frequent meals and taking the medicine with food can help reduce the risk of low blood sugar (hypoglycemia). Maintaining proper hydration and avoiding excessive alcohol are also recommended.

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270 & 275.

2. Alan J Garber, Daniel S Donovan Jr, Paresh Dandona, Simon Bruce, Jong-Soon Park. Efficacy of glyburide/metformin tablets compared with initial monotherapy in type 2 diabetes. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. August 2003. [Accessed on 14th November 2025]. 

3. Virendra Rambiritch, Breminand Maharaj, and Poobalan Naidoo. Glibenclamide in patients with poorly controlled type 2 diabetes: a 12-week, prospective, single-center, open-label, dose-escalation study. NIH. National Library of Medicine. National Center of Biotechnology Information. PMC. PubMed Central. April 2014 [Accessed on 14th November 2025]. 

4. Bristol-Myers Squibb Company; U.S. Food & Drug Administration; [Revised in December 2018] [Accessed on 14th November 2025]. 

5.Central Drugs Standard Control Organization. Glibenclamide+Metformin. [Accessed on 14th November 2025]. 

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Fasting Blood Sugar (FBS)
• Random Blood Sugar (RBS)
• Extended Diabetes Care
• Advance Diabetes Care
• Comprehensive Diabetes Care

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 14 Nov 2025 | 02:51 PM(IST)