GLIOTEM 100mg Capsule 1's

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Drug Information for GLIOTEM 100mg Capsule 1's

What is GLIOTEM?

  • GLIOTEM contains temozolomide which belongs to an anti-tumour agent







What GLIOTEM is used for?

GLIOTEM is used for the treatment of specific forms of brain tumours such as,

  • newly-diagnosed glioblastoma multiforme
  • anaplastic astrocytoma

GLIOTEM is used in these tumours if they return or get worse after standard treatment.

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Talk to your doctor before taking this medicine, if you:

  • are allergic to temozolomide or any of the other ingredients of this medicine
  • have had an allergic reaction to dacarbazine (an anticancer medicine sometimes called DTIC)
  • have severely reduced blood cells (myelosuppression), such as your white blood, red blood and platelet count
  • have serious form of chest infection called Pneumocystis jirovecii pneumonia (PCP)
  • have ever had or might now have a hepatitis B infection
  • may have a small risk of other changes in blood cells, including leukaemia
  • more prone to infections, bruising or bleeding
  • have liver or kidney problems
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  • Effective contraceptive precautions must be taken by patients who are taking GLIOTEM
  • You should stop breast-feeding while receiving treatment with GLIOTEM
  • If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
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  • Do not give this medicine to children under the age of 3 years because it has not been established
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  • GLIOTEM may make you feel tired or sleepy. In this case, do not drive or use any tools or machines or cycle until you see how this medicine affects you
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  • Tell your doctor if you are taking, have recently taken or might take any other medicines including medicine obtained without prescription, vitamin supplements and herbal products
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  • Always take this medicine exactly as your doctor has told you
  • Your doctor will work out your dose of GLIOTEM. This is based on your size (height and weight) and if you have a recurrent tumour and have had chemotherapy treatment in the past
  • Take your prescribed dose of GLIOTEM once a day, preferably at the same time each day
  • Take this medicine on an empty stomach; for example, at least one hour before you plan to eat breakfast. Swallow it whole with a glass of water
  • Do not open, crush or chew the medicine

If you take more GLIOTEM

  • If you accidentally take more GLIOTEM than you were told to, contact your doctor immediately

If you forget to take GLIOTEM

  • Take the missed dose as soon as possible during the same day
  • Do not take a double dose to make up for a forgotten dose, unless your doctor tells you to do so

If you stop taking GLIOTEM

  • Do not stop taking this medicine unless your doctor has told you to do so
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Like all medicines, this medicine can cause side effects, although not everybody gets them.






  • a severe allergic (hypersensitive) reaction (hives, wheezing or other breathing difficulty)
  • uncontrolled bleeding
  • seizures (convulsions)
  • fever, chills
  • severe headache that does not go away
  • a reduction in certain kinds of blood cells. This may cause you to have increased bruising or bleeding, anaemia (a shortage of red blood cells), fever, and reduced resistance to infections
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  • infections, wound infection
  • increased sugar in the blood, loss of weight
  • change in mental status or alertness, anxiety/depression, sleepiness, difficulty speaking, impaired balance, dizziness, confusion, forgetfulness, difficulty concentrating
  • inability to fall asleep or stay asleep, tingling sensation, bruising, shaking, abnormal or blurry vision, double vision
  • hearing impairment
  • shortness of breath, cough
  • blood clot in the legs, fluid retention, swollen legs
  • stomach upset
  • difficulty swallowing, dry mouth
  • skin irritation or redness, dry skin, itching
  • muscle weakness, painful joints, muscle aches and pains
  • frequent urination, difficulty with holding your urine
  • allergic reaction, fever,
  • radiation injury, face swelling, pain
  • abnormal taste
  • reduced number of blood cells (neutropenia or lymphopenia, thrombocytopenia)
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  • flu-like symptoms, red spots under the skin
  • low potassium level in the blood, weight gain
  • mood swings, hallucination and memory impairment, partial paralysis, impaired coordination, impaired sensations, partial loss of vision
  • dry or painful eyes, deafness, infection of the middle ear, ringing in the ears, earache, palpitations (when you can feel your heart beat)
  • blood clot in the lung, high blood pressure, pneumonia, inflammation of your sinuses, bronchitis, a cold or the flu
  • swollen stomach, difficulty controlling your bowel movements, haemorrhoids
  • peeling skin, increased skin sensitivity to sunlight, change in skin colour, increased sweating
  • muscle damage, back pain
  • vaginal bleeding, sexual impotence, absent or heavy menstrual periods, vaginal irritation, breast pain
  • hot flushes, shivering, discoloration of your tongue, change in your sense of smell, thirst, tooth disorder
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  • cough, infections including pneumonia
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  • skin redness, urticaria (hives), skin eruption, allergic reactions
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  • Keep this medicine out of reach of children
  • Do not use this medicine after the expiry date
  • Store at room temperature (15-25ºC)
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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