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Gemidro 150mg Tablet 1's
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INTRODUCTION
GEMIDRO 150MG TABLET contains Ibandronic acid which belongs to the group of medicines called Bisphosphonates. It is used to reverse bone loss and increase bone mass in women, lower chances of bone fracture and to treat postmenopausal osteoporosis.
Osteoporosis is a thinning and weakening of the bones, which is common in women after the menopause. Symptoms include back pain, loss of height over time, stooped posture and easy bone fracture.
Along with this treatment, your doctor might advise you to maintain a healthy lifestyle like eating a balanced diet rich in calcium and vitamin D, walking or any other weight-bearing exercise, maintaining good oral hygiene, avoiding smoking and alcohol consumption. Prior to the treatment your doctor might want you to take X rays to understand your existing condition.
GEMIDRO 150MG TABLET is not recommended for use in patients having certain problems with gullet/food pipe (esophagus) such as narrowing or difficulty swallowing, can’t stand or sit upright for at least one hour at a time and low blood calcium levels.
Before taking GEMIDRO 150MG TABLET, inform your doctor if you have or ever had problems with mouth or teeth (poor dental health, gum disease or tooth extraction), have not had a dental check up for a long time, are a smoker, have cancer, disturbances of mineral metabolism (vitamin D deficiency), kidney disease, swallowing or digestive problems.
GEMIDRO 150MG TABLET is not recommended for use in pregnant and breastfeeding women. GEMIDRO 150MG TABLET is not recommended for use in children and adolescents below 18 years of age. The most common side effects of taking GEMIDRO 150MG TABLET are headache, heartburn, discomfort in swallowing, nausea, indigestion and stomach pain.
USES OF GEMIDRO 150MG TABLET
- Treats postmenopausal osteoporosis
HOW GEMIDRO 150MG TABLET WORKS
GEMIDRO 150MG TABLET lowers osteoclast activity, which can help to reduce pain and strengthen the bone. It also reduces the amount of calcium that is lost from the bones and aids in the normalisation of blood calcium levels.
DIRECTIONS FOR USE
Take GEMIDRO 150MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. For the next one hour after taking the medicine do not lie down, eat or drink anything. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.
SIDE EFFECTS OF GEMIDRO 150MG TABLET
COMMON
- headache
- heartburn, discomfort in swallowing, stomach pain (may be due to an inflammation of stomach), indigestion, nausea, diarrhea
- muscle cramps, stiffness of your joints and limbs
- flu-like symptoms (fever, shaking, shivering, a feeling of discomfort, bone pain and aching muscles and joints)
- rash
UNCOMMON
- dizziness
- flatulence (farting, feeling bloated)
- back pain
- feeling tired and exhausted
- asthma attacks
RARE
- inflammation of the duodenum (first section of the bowel) causing stomach pain
- hives
Stop taking GEMIDRO 150MG TABLET and consult your doctor immediately if you experience any of the following side effects:
- severe pain in the chest, severe pain after swallowing food or drink, severe nausea or vomiting, difficulty in swallowing, severe inflammation of gullet/food pipe, possibly with sores or constriction of the food pipe
- itching, swelling of your face, lips, tongue and throat with difficulty breathing.
- persistent eye pain and inflammation
- new pain, weakness or discomfort in your thigh, hip or groin (possible unusual fracture of the thigh bone)
- any problems with mouth or teeth (loose teeth, pain or swelling or non-healing of sores or discharge could be signs of osteonecrosis of the jaw)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lot of fluids such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Consult your doctor if the symptom gets worse.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals while taking this medicine. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Stomach Pain
Try to take rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
Tiredness
Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedGEMIDRO 150MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking GEMIDRO 150MG TABLET.
BREASTFEEDING
ContraindicatedGEMIDRO 150MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking GEMIDRO 150MG TABLET.
DRIVING AND USING MACHINES
Use with CautionGEMIDRO 150MG TABLET has no effect on your ability to drive and use machines.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking GEMIDRO 150MG TABLET.
KIDNEY
Use with CautionGEMIDRO 150MG TABLET should be used with caution in patients whose kidneys are not functioning normally. Consult your doctor before taking GEMIDRO 150MG TABLET.
ALLERGY
ContraindicatedDo not take GEMIDRO 150MG TABLET if you are allergic to ibandronic acid or any other ingredients of this medicine.
USE IN PEDIATRICS
ContraindicatedGEMIDRO 150MG TABLET is not recommended for use in children and adolescents below 18 years of age. Consult your child’s doctor for advice.
OTHERS
GEMIDRO 150MG TABLET is not recommended for use if you:
- have certain problems with your food pipe (oesophagus) such as narrowing or difficulty swallowing.
- have difficulty in standing or sitting upright for at least one hour at a time
- have or had low blood calcium levels in the past
Before taking GEMIDRO 150MG TABLET, inform your doctor if you:
- have any problems with mouth or teeth (such as poor dental health, gum disease or a planned tooth extraction)
- have not received routine dental care or not had a dental check up for a long time
- are a smoker
- have cancer
- are under dental treatment or will undergo dental surgery (like tooth extractions)
- disturbances of mineral metabolism (such as vitamin D deficiency)
- have any swallowing or digestive problems
- intolerant to some sugars (lactose)
INTERACTIONS
A. Drug - Drug interactions:
Before taking GEMIDRO 150MG TABLET, inform your doctor if you are taking any of the following medicines:
- supplements containing calcium, magnesium iron or aluminum (used to treat mineral deficiency)
- acetylsalicylic acid and other nonsteroidal anti-inflammatory medicines (NSAIDs) (Ex. ibuprofen, diclofenac and naproxen)
- corticosteroids Ex. prednisolone, dexamethasone (used to treat inflammatory conditions)
B. Drug - Food interaction:
GEMIDRO 150MG TABLET should not be taken with food as it makes the medicine less effective. Consult your doctor before taking GEMIDRO 150MG TABLET.
Overdosage:
If you or anyone else accidentally take too much of GEMIDRO 150MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are upper gastrointestinal adverse reactions (such as stomach upset, dyspepsia, esophagitis, gastritis or ulcer) or hypocalcemia (low levels of calcium in the blood).
SYNOPSIS
| Drug | : | Ibandronic acid |
| Pharmacological Category | : | Bisphosphonates |
| Therapeutic Indication | : | Post-menopausal osteoporosis |
| Dosage Forms | : | Tablet, Injection |
MORE INFORMATION
- Keep GEMIDRO 150MG TABLET out of reach of children
- Store below 30°C
FAQs ABOUT GEMIDRO 150MG TABLET
Q: What lifestyle changes I should make while taking GEMIDRO 150MG TABLET?
A: While taking GEMIDRO 150MG TABLET your doctor might advise you to maintain a healthy lifestyle like eating a balanced diet rich in calcium and vitamin D, walking or any other weight-bearing exercise, maintaining good oral hygiene, avoiding smoking and alcohol consumption.
Q: Why can you not lie down after taking GEMIDRO 150MG TABLET?
A: One should not lie down after taking GEMIDRO 150MG TABLET as there is a possibility that the medication might come back up into the esophagus (food pipe) and even damage the esophagus. Staying upright will help the medicine to settle down quickly in your stomach and prevent side effects like heartburn and pain.
Q: How does GEMIDRO 150MG TABLET work?
A: GEMIDRO 150MG TABLET lowers osteoclast activity, which can help to reduce pain and strengthen the bone. It also reduces the amount of calcium that is lost from the bones and aids in the normalisation of blood calcium levels.
Q: Can GEMIDRO 150MG TABLET be used in pregnant women?
A: GEMIDRO 150MG TABLET is for use only by postmenopausal women and must not be taken by women who could still have a baby. Consult your doctor for advice before taking GEMIDRO 150MG TABLET.
Q: What happens if I take an overdose of GEMIDRO 150MG TABLET accidentally?
If you take too much of GEMIDRO 150MG TABLET, consult your doctor immediately or visit the nearby hospital as it can cause upper gastrointestinal adverse reactions (such as stomach upset, dyspepsia, esophagitis, gastritis or ulcer) or hypocalcemia (low blood calcium levels).
REFERENCES
1. KD. Tripathi. Drugs Affecting Calcium Balance. Essentials of medical pharmacology. Seventh edition. 2013. Page – 343
2. Maurizio Rossini, Giovanni Orsolini, Silvano Adami, Vidya Kunnathully, Davide Gatti. Osteoporosis treatment: why ibandronic acid? [Accessed on 7th June 2022] https://pubmed.ncbi.nlm.nih.gov/23650954/
3. Hoffmann-La Roche. A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Previously Treated With Bonviva. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in July 2017] [Accessed 7th June 2022] https://clinicaltrials.gov/ct2/show/NCT00081653
4. Zentiva k.s. Electronic Medicines Compendium (EMC). [Revised in October 2022] [Accessed on 7th June 2022] https://www.medicines.org.uk/emc/files/pil.2943.pdf
USEFUL DIAGNOSTIC TESTS
- X ray
- Serum-calcium levels
- Serum vitamin- D levels
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 15 Feb 2023 | 05:17 PM(IST)
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