INTRODUCTION

FEBURIC 40MG contains Febuxostat which belongs to Xanthine oxidase (XO) inhibitor, used to lower blood uric acid levels in adults with gout. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints which can cause sudden, severe pain, redness, warmth and swelling in a joint. This medicine works by reducing uric acid levels. and stops crystals building up, and over time it reduces symptoms.

This medicine is also used to treat and prevent high blood levels of uric acid that may occur when you start to receive chemotherapy for blood cancers. It is not recommended in children and adolescents under 18 years of age. Before taking this medicine, tell your doctor if you have any heart problems, stroke, thyroid problems, or kidney or liver problems. Most common side effects of FEBURIC 40MG are liver problems, diarrhoea, headache, rash, nausea, joint pain and oedema. Take this medicine according to the dose and frequency as advised by your doctor. It may be taken with or without food.

USES OF FEBURIC 40MG

• Treats Gout

HOW FEBURIC 40MG WORKS

FEBURIC 40MG is a Xanthine oxidase inhibitor. It works by reducing uric acid levels which is the chemical that causes gout.

DIRECTIONS FOR USE

Take this medicine according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. It may be taken with or without food.

SIDE EFFECTS OF FEBURIC 40MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller.

Feeling sick (nausea) or indigestion:

Stick to simple normal meals and do not eat rich or spicy foods.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• azathioprine  
• mercaptopurine
• allopurinol
• theophylline

SYNOPSIS

MORE INFORMATION

Store at room temperature below 30°C and keep out of reach of children.

FAQs ABOUT FEBURIC 40MG

What is FEBURIC 40MG used for?

It is used to treat gout in adults. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints.

How long should I take FEBURIC 40MG?

The dose and duration vary from person to person and will be decided by your doctor. Do not stop taking this medicine without the advice of your doctor even if you feel better.

Can I stop taking FEBURIC 40MG on my own if I am fine and have no pain or swelling in joints?

No. Discontinuation of medicine may increase the levels of uric acid. It may also worsen your symptoms.

REFERENCES

1. KD Tripathi MD. Anti-rheumatoid and anti-gout drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 217.

2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents: Pharmacotherapy of Gout. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 997-98.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 534-35.

4. John A. Cuenca, Javier Balda, Ana Palacio, Larry Young, Michael H. Pillinger and Leonardo Tamariz. Febuxostat and Cardiovascular Events: A Systematic Review and Meta-Analysis. Feb 3, 2019; [Accessed Oct 14, 2020] https://www.hindawi.com/journals/ijr/2019/1076189/

5. Rivopharm UK Ltd. Bluepharma Indústria Farmacêutica, S.A. Electronic Medicines Compendium (EMC); [Revised Sep 2018] [Accessed Oct 14, 2020] https://www.medicines.org.uk/emc/files/pil.10521.pdf

6. Takeda Pharmaceuticals America, Inc. 2009, U.S. Food & Drug Administration; [Revised March 2013] [Accessed Oct 14, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021856s011lbl.pdf