INTRODUCTION

EZIMET S OINTMENT is a combination of Mometasone and Salicylic acid which belongs to the group of medicines called Dermatological agents. EZIMET S OINTMENT is used to treat the symptoms of eczema which is a skin condition characterized by patches of skin that have become inflamed, itchy, cracked and rough with few types leading to blisters.

It is generally caused by triggering factors such as nuts and dairy which might also occur due to environmental triggering factors such as smoke, pollen, soaps and fragrances leading to onset of symptoms of eczema.

Avoid applying EZIMET S OINTMENT, if you have rosacea (a skin condition affecting the face), acne (pimples), skin atrophy (thinning of the skin), dermatitis (skin inflammation) around the mouth, genital itching, viral infections such as shingles, chickenpox (viral infection), ulcerated skin and wounds.

Before applying EZIMET S OINTMENT, inform your doctor if you have any skin problems. EZIMET S OINTMENT should be used in pregnant women only if advised by the doctor. If you are a breast-feeding women, consult your doctor before applying EZIMET S OINTMENT. Safety and effectiveness of EZIMET S OINTMENT is not recommended for use in children.

The most common side effects of using EZIMET S OINTMENT are mild to moderate pruritus (itchy skin), burning and stinging sensation of skin, dryness of skin and mild skin atrophy (thin-shiny appearing skin). Consult your doctor if any of the side effects get worse.

USES OF EZIMET S OINTMENT

• Treats symptoms of eczema

HOW EZIMET S OINTMENT WORKS

EZIMET S OINTMENT is used to treat symptoms of eczema, where Mometasone reduces the redness and itchiness of skin by blocking the production of prostaglandin (chemical messenger), which is responsible for causing redness and itchiness of skin and Salicylic acid helps in softening the moisture in the skin which results in the shedding of outer layer of skin thereby providing relief from the symptoms of eczema.

DIRECTIONS FOR USE

Always apply EZIMET S OINTMENT as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. It should not be applied under bandages or similar. Avoid applying the medicine around your eyes or mucous membrane. Your doctor will decide the duration and frequency of using this medicine depending upon severity of the condition.  

SIDE EFFECTS OF EZIMET S OINTMENT

HOW TO MANAGE SIDE EFFECTS

Dry Skin:

Try moisturizing your skin with a lotion 2 to 3 times a day or as often needed. Moisturizers help to keep the area moisturized, so they work best on damp skin. After you take a bath, pat your skin dry then apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes or other chemicals.

Skin itching:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoor. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before using EZIMET S OINTMENT, inform your doctor if you are using any medicines including prescription or non-prescription medicines.

Overdosage:

If you or anyone else accidentally applied too much of EZIMET S OINTMENT, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose includes secondary adrenal insufficiency which might result in weakness, fatigue and weight loss.

SYNOPSIS

MORE INFORMATION

• Keep EZIMET S OINTMENT out of reach of children
• Store EZIMET S OINTMENT at room temperature

FAQs ABOUT EZIMET S OINTMENT

What is EZIMET S OINTMENT used for?

EZIMET S OINTMENT is used to treat symptoms of eczema which is a skin condition characterized by patches of skin that have become inflamed, itchy, cracked and rough with few types leading to blisters that generally occurs due to triggering factors such as nuts, dairy, smoke or pollen.

What happens if you suddenly stop EZIMET S OINTMENT?

If you have been applying EZIMET S OINTMENT for a long time and your skin problem seems to have got better, you should not suddenly stop using the medicine. If you do, you may find that your skin becomes red and may notice a stinging or burning sensation. To avoid this, consult and discuss with your doctor before stopping EZIMET S OINTMENT.

Who should avoid applying EZIMET S OINTMENT?

EZIMET S OINTMENT is not recommended for use in patients allergic to mometasone, salicylic acid, topical polyethylene glycols and/or have rosacea (a skin condition affecting the face), acne (pimples), skin atrophy (thinning of the skin), dermatitis (skin inflammation) around the mouth, cold sores, shingles or chickenpox (viral infection), ulcerated skin and wounds.

How does EZIMET S OINTMENT work?

EZIMET S OINTMENT is used to treat symptoms of eczema, where Mometasone reduces the redness and itchiness of skin by blocking the production of prostaglandin (chemical messenger), which is responsible for causing redness and itchiness of skin and Salicylic acid helps in softening the moisture in the skin which results in the shedding of outer layer of skin thereby providing relief from the symptoms of eczema.

How EZIMET S OINTMENT should be applied at the site of infection?

Always apply EZIMET S OINTMENT as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. It should not be applied under bandages or similar. Avoid applying the medicine around your eyes or mucous membrane. Your doctor will decide the duration and frequency of using this medicine depending upon severity of the condition.   

REFERENCES

1. KD. Tripathi. Drugs Acting on Skin & Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 889 &  895.

2. Asana BioSciences. Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in June 2020] [Accessed on 24th May 2022] https://clinicaltrials.gov/ct2/show/NCT03728504

3. Fabrizio Spada, Tanya M Barnes, and Kerryn A Greive. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. February 2018 [Accessed on 24th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099284/

4. Salicylic Acid Topical. Medline Plus. NIH National Library of Medicine. September 2016  [Accessed on 24th May 2022] https://medlineplus.gov/druginfo/meds/a607072.html

5. Glenmark Pharmaceuticals s.r.o. Electronic medicines compendium (EMC). [Revised in January 2022] [Accessed on 24th May 2022] https://www.medicines.org.uk/emc/files/pil.9994.pdf

6. Bensal HP- salicylic acid ointment. Dailymed. NIH National Library of Medicine. April 2021 [Accessed on 24th May 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4b8ccee9-0f26-416d-a6e5-1261408df899

7. Organon (New Zealand) Limited. New Zealand Medicines and Medical devices Safety Authority (medsafe). [Revised in January 2020]  [Accessed on 24th May 2022] https://www.medsafe.govt.nz/profs/Datasheet/e/Eloconcrointlot.pdf

USEFUL DIAGNOSTIC TESTS

• Patch testing