INTRODUCTION

EUTHYROX contain Levothyroxine sodium which is a synthetic thyroid hormone and is chemically identical to thyroxine produced by the thyroid gland. Treatment with levothyroxine sodium helps in replacing missing thyroid hormone and in all forms of underactive thyroid function (hypothyroidism) or after the removal of the thyroid gland.  Thyroid hormone is vital for the normal growth and development. Lack of right amount of thyroid hormones leads to slowing down in natural functions of our body. Hypothyroidism is a condition where enough thyroid hormone required are not produced by the body. Some of the most common symptoms of hypothyroidism are tiredness, weight gain and feeling depressed. It helps in replacing the thyroxine that your thyroid gland cannot produce and prevent the symptoms of hypothyroidism.

Always take EUTHYROX exactly as prescribed by your doctor. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, or pancreas problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effects such as restlessness, insomnia, diarrhea, changes in menstrual cycle in women etc.

USES OF EUTHYROX

• helps in replacing the thyroxine that your thyroid gland cannot produce and prevent the symptoms of hypothyroidism

HOW EUTHYROX WORKS

Levothyroxine sodium is a synthetic thyroid hormone which is identical to natural occurring thyroid hormone thyroxine or T4, produced by the thyroid gland. Thyroxine regulates the production of another hormone called thyroid stimulating hormone (TSH) which in turn controls how much thyroxine is produced. Levothyroxine sodium regulates TSH production in the same way and therefore, substitutes for a lack of endogenous thyroxine (produced by the thyroid gland).

DIRECTIONS FOR USE

Always take EUTHYROX exactly as prescribed by your doctor. Do not split, chew or crush this medicine. Swallow the medicine whole.

SIDE EFFECTS OF EUTHYROX

HOW TO MANAGE SIDE EFFECTS

Vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Diarrhea:

Drink lots of fluid, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting your doctor.

Headache:

Take rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.

Joint pain:

Apply hot or cold packs. Eat a healthy diet includes enough calcium and vitamin D. Maintain healthy weight to ease stress and strain on your joints. Exercise regularly.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or recently taken any other medicines, including medicines obtained without a prescription or the following:

• medicines to treat diabetes
• anticoagulants such as warfarin, dicoumarol (used to thin the blood)
• amiodarone (used to treat some heart conditions)
• aspirin
• medicines containing oestrogen (e.g. used for hormone replacement therapy or oral contraceptives)
• antidepressants (e.g. sertraline and tricyclic antidepressants such as amitriptyline, imipramine)
• chloroquine and proguanil (used in malaria and rheumatic diseases)
• 5-fluouracil, imatinib and sunitinib (used for the treatment of cancer)
• medicines control your heart rate such as digoxin
• medicines that stimulate the sympathetic nervous system such as adrenaline
• carbamazepine, phenytoin or barbiturates (used to treat epilepsy or seizures)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT EUTHYROX

What EUTHYROX is used for?

It used to treat an underactive thyroid gland (hypothyroidism). Thyroid gland makes thyroid hormone which helps to control the energy levels and growth. It is taken to replace the missing thyroid hormone.

What happens if I take EUTHYROX with food?

The absorption of this medicine in the gut is decreased when taking with some foods and other drugs. Hence patients are usually instructed to take  on an empty stomach 30-60 minutes before food intake to avoid erratic absorption of this medicine.

REFERENCES

1. Roselyn Cristelle I. Mateo and James V. Hennessey; Thyroxine and treatment of hypothyroidism: seven decades of experience; [Published on 2019] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794242/

2. Philippe Colucci, Corinne Seng Yue, Murray Ducharme and Salvatore Benvenga; A Review of the Pharmacokinetics of Levothyroxine for the Treatment of Hypothyroidism; [Published on 2013] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193522/

3. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter – 39; Thyroid and antithyroid drugs; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 1130.

4. Accord, Barnstaple, U.K.; Electronic Medicines Compendium (EMC); [Revised on Feb 2020] [Accessed 09 Oct 2020] https://www.medicines.org.uk/emc/files/pil.5805.pdf

5. Custom Pharmaceuticals Ltd., Health products regulatory authority (HPRA); [Revised on July 2014] [Accessed 09 Oct 2020] https://www.hpra.ie/img/uploaded/swedocuments/2138853.PPA1151_064_001.c4ca368d-f9b6-4592-8f62-e5117afd1ebe.000001Eltroxin%20Combined%20PIL.140708.pdf

USEFUL DIAGNOSTIC TESTS

• Anti-Thyroglobulin Antibody
• Thyroid Function Test
• Thyroid Profile Free
• Thyroid Stimulating Hormone