Esperal Tablet 10'S

Alcohol Addiction Rx required

Best Price* ₹ 34.80 MRP ₹ 43.50
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Torrent Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

ESPERAL TABLET contains Disulfiram which belongs to the group of medicines called Aldehyde Dehydrogenase Inhibitors. It is used to support the treatment of alcohol dependence (or alcohol addiction). It helps to quit the habit of alcoholism in patients having a habit of drinking excessive alcohol (chronic alcoholism).

ESPERAL TABLET helps in reducing alcohol dependence. It creates aversion towards alcohol by creating various unpleasant symptoms (such as flushing, burning sensation, throbbing headache, increased sweating, chest tightness, dizziness, vomiting, visual disturbances and confusion).

Before taking ESPERAL TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, high or low blood pressure, thyroid problems, brain damage, fits or any mental disorders as a precaution.

ESPERAL TABLET should not be used in patients who have already consumed alcohol. It should be used only in patients who have not drunk alcohol for at least 24 hours prior to the first dose. It is also not suitable for use in pregnant or breastfeeding women and in children (aged below 18 years).

The most common side effects of taking ESPERAL TABLET are drowsiness, tiredness, impotence, low sex drive, headache, sleepiness and metallic taste. Consult your doctor if any of these side effect worsens.

USES OF ESPERAL TABLET

  • Treats alcohol dependence

HOW ESPERAL TABLET WORKS

ESPERAL TABLET helps in reducing alcohol dependence. It acts by blocking the actions of certain enzymes (such as aldehyde dehydrogenase) within the body that helps in breaking down a substance called as acetaldehyde.

As a result, it leads to the accumulation of an excessive amount of acetaldehyde in the body causing unpleasant physical reactions (such as flushing, burning sensation, throbbing headache, increased sweating, chest tightness, dizziness, vomiting, visual disturbances and confusion) that can create aversion towards alcohol which will eventually help in quitting alcoholism.

DIRECTIONS FOR USE

Take ESPERAL TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not consume alcohol for at least 24 hours before taking the first dose of ESPERAL TABLET.

Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF ESPERAL TABLET

COMMON

  • drowsiness, tiredness
  • impotence, low sex drive
  • headache, sleepiness
  • acne, skin rash
  • metallic taste
  • depression, mania (abnormal excitement)
  • nerve pain, pain in hands and legs
  • nausea, vomiting

RARE

Stop taking ESPERAL TABLET and contact your doctor immediately if you experience any of the following side effects:

  • allergic reactions include skin rash, itching and redness.

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try to take ESPERAL TABLET with or just after meals. Stick to simple meals and avoid oil-rich or spicy foods. Consult your doctor if the nausea worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Drowsiness:

Try to rest and relax. Get enough sleep. Avoid driving or operating heavy tools or machinery while you feel drowsy. Avoid the consumption of alcohol as it could aggravate your drowsiness. Contact your doctor if the condition worsens.

WARNING & PRECAUTIONS

PREGNANCY

ESPERAL TABLET is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

BREASTFEEDING

ESPERAL TABLET is generally not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

ESPERAL TABLET may cause drowsiness and tiredness. Therefore, do not drive or operate any heavy tools or machinery if your ability is affected by [GBNEYWORD].

ALCOHOL

Avoid consumption of alcohol while taking ESPERAL TABLET as it may leads to serious unwanted side effects.

KIDNEY

ESPERAL TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.

LIVER

ESPERAL TABLET should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.

ALLERGY

Do not take ESPERAL TABLET if you are allergic to Disulfiram.

LUNGS

[GBNEYWORD] should be used with caution in patients with lung diseases such as asthma. Therefore, consult your doctor before taking it.

HEART DISEASE

ESPERAL TABLET is not recommended for use in patients with severe heart diseases (such as heart failure or coronary occlusion). Therefore, consult your doctor before taking it.

OTHERS

ESPERAL TABLET is not recommended for use if you:

  • have consumed an excessive amounts of alcohol (alcohol intoxication)
  • have high blood pressure
  • have a severe mental disorder or any personality disorder
  • had stroke recently

Before taking ESPERAL TABLET, inform your doctor if you:

  • have diabetes
  • have low blood pressure
  • have epilepsy
  • have any form of damage in the brain
  • have hypothyroidism (low thyroid functions)

Use in pediatrics:

ESPERAL TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use in geriatrics:

ESPERAL TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.

INTERACTIONS

A) Drug - Drug interactions:

Before taking ESPERAL TABLET, inform your doctor if you are taking any of the following medicines such as:

  • warfarin (a medicine used to reduce blood clotting)
  • medicines used to treat epilepsy (Ex. phenytoin and paraldehyde)
  • theophylline (a medicine used to treat asthma)
  • medicines used to reduce anxiety (such as chlordiazepoxide and diazepam)
  • opioid analgesics (used for pain relief) such as pethidine and morphine
  • medicines used to stimulate the brain (such as amphetamine, dextroamphetamine)
  • medicines used to treat mental illness (such as pimozide and chlorpromazine)
  • medicines used to treat tuberculosis (Ex. isoniazid, rifampicin)
  • metronidazole (a medicine used to treat parasite infection)
  • amitriptyline (a medicine used to treat depression)
  • alcohol-containing medicines (such as cough syrups)

Overdosage:

If you or anyone else accidentally took more ESPERAL TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, stomach pain, diarrhoea, headache, drowsiness, fatigue, mental disorders, tiredness, rapid heartbeat, rapid breathing, high body temperature, low blood pressure, loss of muscle control and/or high blood sugar.

SYNOPSIS

Drug :   Disulfiram
Pharmacological Category :   Aldehyde Dehydrogenase Inhibitor
Therapeutic Indication :   Chronic Alcoholism         
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep ESPERAL TABLET out of reach of children
  • Store ESPERAL TABLET at a room temperature

FAQs ABOUT ESPERAL TABLET

What is the use of ESPERAL TABLET?

ESPERAL TABLET is used to support the treatment of alcohol dependence (or alcohol addiction). It helps to quit the habit of alcoholism in patients having a habit of drinking excessive alcohol (chronic alcoholism).

How ESPERAL TABLET works in my body?

ESPERAL TABLET acts by blocking the actions of certain enzymes (such as aldehyde dehydrogenase) within the body that helps in breaking down a substance called as acetaldehyde. This leads to the accumulation of an excessive amount of acetaldehyde in the body causing unpleasant physical reactions which will eventually help in quitting alcoholism.

 Is ESPERAL TABLET safe?

ESPERAL TABLET is considered safe at doses prescribed by the physician.

What are the side effects of taking ESPERAL TABLET?

The most common side effects of taking ESPERAL TABLET are drowsiness, tiredness, impotence, low sex drive, headache, sleepiness and metallic taste. Consult your doctor if any of these side effects worsen.

Can I stop taking ESPERAL TABLET once my symptoms subside?

No. Take ESPERAL TABLET every day until your doctor tells you to stop. Do not stop taking this medicine abruptly or reduce the dose without consulting your doctor. Your doctor will assess your disease condition regularly and will increase or decrease the dose accordingly.

Will ESPERAL TABLET be more effective if taken at higher doses?

Always consume the dose prescribed for you by your physician. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and severity of the disease. Do not take a higher dose of this medicine without consulting your doctor as it could lead to unwanted side effects. If your symptoms are not relieved by the prescribed dose, consult your doctor so that he might adjust the dose according to your health condition or can suggest an alternative therapy.

I’m pregnant. Can I use ESPERAL TABLET?

ESPERAL TABLET is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

Can ESPERAL TABLET be used in adolescents?

ESPERAL TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

What happens when you forget to take ESPERAL TABLET?

If you forget to take ESPERAL TABLET, take it as soon as you remember. However, if it's time for the next dose, skip the missed dose and take the next dose. Do not take a double dose to compensate for the missed dose.

Can I take ESPERAL TABLET daily?

Take ESPERAL TABLET as advised by your physician. Your doctor will evaluate your health condition and suggest whether can you take ESPERAL TABLET every day or not.

REFERENCES

1. KD. Tripathi. Ethyl and Methyl alcohol. Drugs acting on CNS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 394.

2. Maranda Stokes; Sara Abdijadid. Disulfiram. StatPearls [Internet]. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. [Revised in November 2021]. [Accessed on 2nd December 2022] https://www.ncbi.nlm.nih.gov/books/NBK459340/

3. Marilyn D. Skinner,  Pierre Lahmek,  Héloïse Pham and Henri-Jean Aubin. Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2014. [Accessed on 2nd December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919718/

4. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 2nd December 2022] https://www.medicines.org.uk/emc/files/pil.11168.pdf

5. Leeford Healthcare Pvt Ltd. Recopress 500. [Accessed on 2nd December 2022] https://www.leeford.in/product/791/recopress-500

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    DISULFIRAM 250MG
    Hsn Code
    30049099
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Esperal Tablet 10'S

Esperal Tablet 10'S Mkt: Torrent Pharmaceuticals Ltd

M.R.P.: Rs.43.50
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