INTRODUCTION

ERYTHEGO contains Brimonidine used for the topical skin treatment of facial redness of rosacea in adult patients. It constricts the blood vessels in the skin thereby reducing the redness of rosacea. Rosacea is a skin condition characterised by redness and visible blood vessels in your face. It may also produce small, red bumps filled with pus.

Brimonidine works by constricting the blood vessels in the skin thereby reducing the redness of rosacea. This medicine is not recommended in children adolescents between 2 and 18 years of age. Do not use ERYTHEGO on irritated skin or open wounds as this may result in low blood pressure or dizziness. Avoid contact with eyes and mucous membranes such as the mouth and inside of the nose. In case of accidental contact, rinse with water. The common side effects are redness, itching and flushing of skin.

USES OF ERYTHEGO

• Treats Rosacea

HOW ERYTHEGO WORKS

ERYTHEGO works by constricting the blood vessels in the skin thereby reducing the redness of rosacea.

DIRECTIONS FOR USE

Always use as instructed by your doctor. Check the label for directions before use. It is for external use only. Do not use ERYTHEGO on irritated skin or open wounds as this may result in low blood pressure or dizziness. Avoid contact with eyes and mucous membranes such as the mouth and inside of the nose. In case of accidental contact, rinse with water. The common side effects are redness, itching and flushing of skin.

SIDE EFFECTS OF ERYTHEGO

HOW TO MANAGE SIDE EFFECTS

Redness:

Cold water helps to bring the redness down. Apply aloe vera and cucumber to ease the redness.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• monoamine oxidase (MAO) inhibitors
• anaesthetics, sedatives, opiates, barbiturates
• chlorpromazine, methylphenidate or reserpine  
• clonidine
• medicines to treat heart condition or for lowering blood pressure
• prazosin and isoprenaline

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ERYTHEGO

Can I use ERYTHEGO every day?

Yes, it can be used for as long as instructed by your doctor. Do not apply more than once a day.

Why does my face sometimes seem redder after using ERYTHEGO?

Some may experience worsening of redness, flushing or burning feeling of the skin. Usually it is seen within the first 2 weeks of starting treatment. Consult your doctor for advice.

Does ERYTHEGO has adverse effect on patients with cardiovascular disease?

Alpha-2 adrenergic agonists can lower blood pressure. Hence this gel should be used with caution in patients with severe or unstable or uncontrolled cardiovascular disease.

REFERENCES

1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 297.

2. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 144.

3. Andrew William Johnson and Sandra Marchese Johnson. The Role of Topical Brimonidine Tartrate Gel as a Novel Therapeutic Option for Persistent Facial Erythema Associated with Rosacea: Dermatology and therapy. Jun 26, 2015 [Accessed Dec 3, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580655/

4. Galderma Canada Inc., Electronic Medicines Compendium (EMC); [Revised Aug 2, 2018] [Accessed Dec 3, 2020] https://www.galderma.com/sites/g/files/jcdfhc196/files/inline-files/Onreltea%20English%20PM.pdf

5. Galderma laboratories, (USA). 1996; U.S. Food & Drug Administration; [Revised Aug 2013] [Accessed Dec 3, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204708lbl.pdf