Endace 40mg Tablet 10'S

Cancer/Oncology Rx required

Best Price* ₹ 249.28 MRP ₹ 311.60
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Samarth Life Sciences Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

Check Availability & Expiry

PINCODE:


INTRODUCTION

ENDACE 40MG contains Megestrol which belongs to the group of medicines called Antineoplastics. It is used in the treatment of certain types of cancer known as hormone-dependent cancer (a type of cancer that is dependent on a hormone for growth and survival like estrogen and progesterone hormones), which includes breast cancer (cells of the breasts start to grow abnormally, resulting in change in the size, shape, skin of the breast, peeling of the skin, newly inverted nipple, redness or pitting of skin over breast and breast lumps).

Megestrol interferes with the estrogen cycle, resulting in lowering of luteinizing hormone that triggers the process of releasing egg from the ovaries and estrogen (female sex hormone), release from the anterior pituitary gland. This type of action helps in treating hormone dependent cancers including breast cancer. Your doctor might want to take kidney tests and certain blood tests to understand your existing condition.

Before taking ENDACE 40MG inform your doctor if you have severe liver problems, intolerant to certain sugar, history of blood clots or diabetes. ENDACE 40MG is not recommended for use in pregnant or breastfeeding women. ENDACE 40MG is not recommended for use in children and it should be used with caution in elderly patients. The most common side effects of taking ENDACE 40MG are weight gain, shortness of breath, diarrhea, tiredness, constipation, and hair loss. Consult your doctor if any of the symptoms worsen.

USES OF ENDACE 40MG

  • Treats certain types of hormone-dependent cancer (including breast cancer)

HOW ENDACE 40MG WORKS

ENDACE 40MG works by interfering with the estrogen cycle, which results in lowering of luteinizing hormone that triggers the process of releasing egg from the ovaries and estrogen (female sex hormone), release from the anterior pituitary gland. This type of action helps in treating hormone dependent cancers including breast cancer.

DIRECTIONS FOR USE

Take ENDACE 40MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ENDACE 40MG

COMMON

  • increase in appetite, weight gain
  • shortness of breath
  • hot flushes (reddening of the face, neck)
  • high blood pressure, increased blood sugar
  • rounded face
  • constipation
  • swelling of a vein due to blood clot, blood clot in lungs
  • changes in mood
  • numbness, pain or tingling in fingers or thumb
  • heart attack
  • hair loss
  • diarrhoea
  • tiredness, feeling weak
  • impotence
  • passing wind
  • needing to urinate often
  • vomiting
  • changes in vaginal bleeding (breakthrough bleeding, spotting)
  • buildup of fluid which causes swelling (in ankles)
  • pain, rash, hives

RARE

Stop taking ENDACE 40MG and contact your doctor immediately if you experience any of the following side effects:

  • signs of blood clot (such as loss of coordination, slurred speech, pain in groin, pain or numbness in arm or leg, shortness of breath, weakness, headache, and fainting)
  • signs of allergic reaction such as swelling of the face, lips, or tongue, skin rash, difficulty breathing

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lot of fluids such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.

Constipation:

Eat fiber rich foods such as fresh fruits, vegetables, cereals and drink enough water. Exercise more regularly. Consult your doctor if the symptom does not improve.

Vomiting:

Stick to simple meals and avoid eating oily or spicy food. Do not perform any strenuous activity immediately after eating. If the symptom does not improve, contact your doctor.

Passing wind (Flatulence):

Eat smaller and frequent meals, exercise regularly. If the symptom does not improve, contact your doctor.

Tiredness:

Drink plenty of fluids and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. If the symptom does not improve, contact your doctor.

 

WARNING & PRECAUTIONS

PREGNANCY

ENDACE 40MG is not recommended for use in pregnant women or women trying to become pregnant. Consult your doctor before taking it.

BREASTFEEDING

ENDACE 40MG is not recommended for use in breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES

ENDACE 40MG does not affect your ability to drive or use machines.

LIVER

ENDACE 40MG should be used with caution in patients with severe liver problems. Consult your doctor before taking it.

ALLERGY

Do not take ENDACE 40MG if you are allergic to Megestrol or any of the other ingredients of this medicine.

OTHERS

Before taking ENDACE 40MG, inform your doctor if you have:

  • diabetes
  • history of blood clot
  • intolerance to certain sugars

Use in pediatrics:

ENDACE 40MG is not recommended for use in children. Consult child’s doctor for advice.

Use in geriatrics:

ENDACE 40MG should be used with caution in elderly patients (above 65 years of age) with regular monitoring of kidney function. Consult your doctor before taking ENDACE 40MG.

INTERACTIONS

A. Drug - Drug interactions:

Before taking ENDACE 40MG, inform your doctor if you are taking any medicines including prescription, over the counter medicines, vitamins and herbal supplements.

Overdosage:

If you or anyone else accidentally take too much of ENDACE 40MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are diarrhoea, nausea, abdominal pain, shortness of breath, cough, abnormality in walking, lack of energy, and chest pain.

SYNOPSIS

Drug :  

Megestrol

Pharmacological Category :  

Progestins

Therapeutic Indication :  

Hormone-dependent cancers (Breast cancer)

Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep ENDACE 40MG out of reach of children
  • Store at room temperature

FAQs ABOUT ENDACE 40MG

What is ENDACE 40MG used for?

ENDACE 40MG is used in the treatment of certain types of cancer known as hormone-dependent cancer (is a type of cancer that is dependent on a hormone for growth and survival like estrogen and progesterone hormones), which includes breast cancer.      

Can ENDACE 40MG be used in pregnant women?

No, ENDACE 40MG is not recommended for use in pregnant women or women who are planning to have a baby and also breastfeeding women. Consult your doctor before taking ENDACE 40MG.

What if I forget to take a dose of ENDACE 40MG?

You should take ENDACE 40MG immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.

What if I take more dose of ENDACE 40MG than the required dose?

If you or anyone else accidentally take too much of ENDACE 40MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are diarrhea, nausea, abdominal pain, shortness of breath, cough, abnormality in walking, lack of energy, and chest pain.

Can ENDACE 40MG be used in liver conditions?

ENDACE 40MG should be used with caution in patients with severe liver disease. Your doctor may adjust the dose depending upon the severity of the liver impairment. Consult your doctor before taking ENDACE 40MG if you have liver disease.

REFERENCES

1. KD Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology.  Eighth Edition. 2019. Page – 341.

2. Graciela Berenstein Zulma Ortiz. Megestrol acetate for treatment of anorexia-cachexia syndrome. [Revised in April 2005] [Accessed on 17th June 2022] https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004310.pub2/abstract

3. Chris Manikkuttiyil, Hoang Nguyen. Megestrol [Revised in July 2021] [Accessed on 17th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK559205/

4. Haupt Pharma Amareg GmbH. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 17th June 2022] https://www.medicines.org.uk/emc/files/pil.11135.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    Megestrol Acetate 40 MG
    Hsn Code
    30043919
ALTERNATE BRANDS
Megahenz 40mg Tablet 10'S
Prescription Cancer/Oncology Rx required
Rs.250.00
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Endace 40mg Tablet 10'S

Endace 40mg Tablet 10'S Mkt: Samarth Life Sciences Pvt Ltd

M.R.P.: Rs.311.60
Copyright© 2022. All Rights Reserved.