DUOJET LD Respules 5X2.5ml

Introduction About DUOJET LD RESPULES

DUOJET LD RESPULES is a combination of Ipratropium and Levosalbutamol which belongs to the group of medicines called Bronchodilator agents and Adrenergic beta-agonists, respectively. DUOJET LD RESPULES is used to manage bronchospasm (tightened airway muscles) associated with chronic obstructive pulmonary disease (inflammatory lung disease) in patients who require more than one bronchodilator (medication) to help them in easy of breathing.

DUOJET LD RESPULES is not recommended for use in patients allergic to ipratropium, levosalbutamol, and/or atropine.

Before using DUOJET LD RESPULES, inform your doctor if you have high blood pressure, seizures, diabetes, narrow angle glaucoma (increased eye pressure), lung problems (such as asthma), heart problems (such as coronary insufficiency, cardiac arrhythmias), kidney problems (such as renal impairment), and/or liver problems (such as hepatic impairment).

DUOJET LD RESPULES should be used with caution during pregnancy and in women planning for pregnancy. It is also used with caution in breastfeeding women only if necessary.

DUOJET LD RESPULES is not recommended for use in children (aged less than 6 years). It should be used with caution in children and adolescents (aged 6 to 18 years). Consult your doctor before administering DUOJET LD RESPULES.

The most common side effects of using DUOJET LD RESPULES are headache, dizziness, nervousness, cough, sore throat, local irritation, dry mouth, nausea, and/or diarrhoea. Consult your doctor if any of these symptoms worsens.

Uses Of DUOJET LD RESPULES

• Manage bronchospasm associated with chronic obstructive pulmonary disease (inflammatory lung disease) in affected individuals

How DUOJET LD RESPULES Works

DUOJET LD RESPULES provides ease in breathing from bronchospasm (constricted airway muscles), where Ipatropium and Levosalbutamol work together to relax airway muscles which results in widening of airways providing relief from obstructive airflow and easy in breathing from bronchospasm associated with chronic obstructive pulmonary disease in affected individuals.

How to use DUOJET LD RESPULES

DUOJET LD RESPULES should be administered only by a nebulizer (with a face mask connected to an air compressor) under the direction of a physician. It is for inhalation use only. Remove the pouch and tear one respule. Twist the cap to open the respule. Squeeze the content into the reservoir of nebulizing chamber and discard the respule after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of DUOJET LD RESPULES

How To Manage Side Effects

Dry mouth:

Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Headache:

If DUOJET LD RESPULES causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking DUOJET LD RESPULES. If it lasts more than a week or severe, inform your doctor.

Nausea and vomiting:

Take DUOJET LD RESPULES with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

Constipation:

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

Diarrhoea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.

Warning & Precautions

Pregnancy

DUOJET LD RESPULES should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary.  Consult your doctor before using the medicine.

Breastfeeding

DUOJET LD RESPULES should be used with caution in breastfeeding women only if necessary since it is not known whether the medicine pass through breast milk. Consult your doctor before using the medicine.

Driving and Using Machines

Do not drive/operate machines if DUOJET LD RESPULES affects your ability to drive/operate machines.

Kidney

DUOJET LD RESPULES should be used with caution in patients with kidney problems such are renal impairment. Consult your doctor before using the medicine.

Liver

DUOJET LD RESPULES should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before using the medicine.

Allergy

Do not take DUOJET LD RESPULES if you are allergic to ipratropium, levosalbutamol, atropine, and/or any other ingredients of the medicine.

Lungs

DUOJET LD RESPULES should be used with caution in patients with lung problems such as asthma. Consult your doctor before using the medicine.   

Heart Disease

DUOJET LD RESPULES should be used with caution in patients with heart problems such as coronary insufficiency, cardiac arrhythmias. Consult your doctor before using DUOJET LD RESPULES.

Interactions

A. Drug-Drug interactions:

Before using DUOJET LD RESPULES, inform your doctor if you are taking any of the following medicine:

• short acting bronchodilators (used to quickly relieve/stop sudden asthma symptoms) Ex. albuterol, levalbuterol
• medicines used to manage high blood pressure such as beta-adregenic/receptor blocking agents (Ex. propanolol, metoprolol, atenolol)
• diuretics (used to manage high blood pressure) Ex. chlorothiazide, chlorthalidone
• digoxin (used to manage irregular heartbeats)
• monoamine oxidase inhibitors/tricyclic antidepressants (medicines used to manage depression) Ex. selegiline, phenelzine, amitriptyline, imipramine
• anticholinergic agents (medicines used to block acetylcholine) Ex. atropine, benztropine

Overdosage:

If you or anyone else accidentally take too much of DUOJET LD RESPULES, then consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are seizures, chest pain, high/low blood pressure, fast heartbeat, irregular heartbeat, nervousness, headache, tremor, dry mouth, pounding heartbeat, nausea, dizziness, fatigue, weakness, sleeplessness, hypokalaemia (low potassium level in blood), fast breathing, high fever, restlessness, hallucinations, confusion, and/or cardia arrest.

Synopsis

More Information

• Keep DUOJET LD RESPULES out of reach of children
• Store DUOJET LD RESPULES above 25°C

FAQs About DUOJET LD RESPULES

What is DUOJET LD RESPULES used for?

DUOJET LD RESPULES is used to manage bronchospasm (tightened airway muscles) associated with chronic obstructive pulmonary disease (inflammatory lung disease) in patients who require more than one bronchodilator (medication) to help them in easy of breathing.

What are the side effects of DUOJET LD RESPULES?

The most common side effects of using DUOJET LD RESPULES are headache, dizziness, nervousness, cough, sore throat, local irritation, dry mouth, nausea, and/or diarrhoea. Consult your doctor if any of these symptoms worsens.

How DUOJET LD RESPULES works?

DUOJET LD RESPULES provides ease in breathing from bronchospasm (constricted airway muscles), where Ipatropium and Levosalbutamol work together to relax airway muscles which results in widening of airways providing relief from obstructive airflow and easy in breathing from bronchospasm associated with chronic obstructive pulmonary disease in affected individuals.

How DUOJET LD RESPULES is administered?

DUOJET LD RESPULES should be administered only by a nebulizer (with a face mask connected to an air compressor) under the direction of a physician. It is for inhalation use only. Remove the pouch and tear one respule. Twist the cap to open the respule. Squeeze the content into the reservoir of nebulizing chamber and discard the respule after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Can DUOJET LD RESPULES be used in pregnant and breastfeeding women?

Yes, DUOJET LD RESPULES can be used but with caution in pregnant and breastfeeding women.  Consult your doctor before using DUOJET LD RESPULES.

References

1. K.D. Tripathi. Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia. Essentials of medical pharmacology. Seventh edition. 2013. Page- 116.

2. A S Hossain, U K Barua, G C Roy, S R Sutradhar, I Rahman, G Rahman. Comparison of salbutamol and ipratropium bromide versus salbutamol alone in the treatment of acute severe asthma. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in April 2013] [Accessed on 30th May 2022] https://pubmed.ncbi.nlm.nih.gov/23715360/

3. Chemo Biological. DUOCOPID-3 RESPULES. [Accessed on May 30th May 2022] https://chemobiological.in/duocopid-3-respules/

4. Lupin Limited. Salbair I Neb Transpules 0.63. [Accessed on May 30th May 2022] https://www.lupin.com/our-products/product-finder/?searchkey=salbair

5. JB Pharma. Dutaresp. [Accessed on May 30th May 2022] https://jbpharma.com/our-therapies/

6. Glenmark Pharma. NEBZMART. [Accessed on May 30th May 2022] https://glenmark.b-cdn.net/gpl_pdfs/products/Glenmark%20Pharmaceuticals%20Ltd-%20Product%20List%20as%20on%20October%202022.pdf

7. CiplaMed. DUOLIN LD Respules.  [Revised in August 2020] [Accessed on May 30th May 2022] https://www.ciplamed.com/content/duolin-ld-respules

Author Details

Written By Dr. K .AZEEM HUSSAIN - B.D.S

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 28 Nov 2022 | 10:22 PM(IST)