DOTIN 25mg Tablet 10's

Depression Rx required

Best Price* ₹ 45.30 MRP ₹ 56.62
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Tasmed India (P) Limited * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

DOTIN 25MG contains Dosulepin which belongs to the group of medicines called Antidepressants. It is used in the treatment of depression (mood disorder causing persistent feeling of sadness and loss of interest) and also helps to reduce the feelings of anxiety (intense, excessive, persistent worry and fear about everyday situations), this medicine is used only when other medicines are not suitable.  

DOTIN 25MG is not recommended for use in patients with liver problems, irregular heartbeat or any other heart problems, mania (feeling over excited with unusual behaviour), glaucoma (increased pressure in eye), prostate problems and fits.

Before taking DOTIN 25MG inform your doctor if you have any planned surgeries (such as dental or general surgery), intolerance to certain sugars and thyroid problems. Avoid consumption of alcohol during treatment with DOTIN 25MG as it can make the drowsiness worse.    

DOTIN 25MG should be used in pregnant and breast-feeding women only if clearly advised by the doctor. It is not recommended for use in children and adolescents (below the age of 18 years) and it should be used with caution in elderly patients due to increased risk of certain side effects.  

The most common side effects of taking DOTIN 25MG are dry mouth, blurred vision, dizziness, constipation, sedation and difficulty in passing urine. Consult with your doctor if any of the side effect worsens.

USES OF DOTIN 25MG

  • Treats depression
  • Reduce the feelings of anxiety

HOW DOTIN 25MG WORKS

DOTIN 25MG acts on central nervous system (CNS) which works by enhancing the activity of certain neurotransmitters (such as serotonin and noradrenaline) in the brain. It also works by stopping the reabsorption of neurotransmitters into the nerve cells in the brain. Thus, results in prolonging their effects and helps to relieve depression and lighten the mood.

DIRECTIONS FOR USE

Take DOTIN 25MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DOTIN 25MG

COMMON

  • dry mouth
  • blurred vision
  • heartbeat changes
  • dizziness
  • constipation
  • sedation
  • difficulty in passing urine

UNCOMMON

  • severe allergic reaction (skin rash, itching, swollen face or tongue, collapse, shortness of breath, collapse)
  • severe low blood pressure
  • increased sweating
  • tiredness or sleepiness
  • confusion and hallucination (strange vision or sounds)
  • tremors
  • changes in libido (sex drive)

RARE

  • severe mood changes such as extreme excitability

Stop taking DOTIN 25MG and inform your doctor immediately if you experience any of the following side effects:

  • skin rash or difficulty in breathing
  • thoughts of harming or killing yourself
  • bone marrow depression or reduction in some blood cells (signs include unusual bruising, abnormal bleeding, mouth ulcers, sore throat and fever)
  • liver problems associated with yellowing of the skin and eyes (jaundice)
  • convulsions (fits)
  • irregular heartbeat (more common with high dosage)

HOW TO MANAGE SIDE EFFECTS

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatment for constipation.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets worse.

Tiredness:

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

DOTIN 25MG should be used in pregnant women only if clearly advised by your doctor. Consult your doctor before taking it.

BREASTFEEDING

DOTIN 25MG should be used in breastfeeding women only if clearly advised by your doctor. Consult your doctor before taking it.  

DRIVING AND USING MACHINES

Do not drive or use machines if you feel drowsy after taking DOTIN 25MG. Consult your doctor for advice.

ALCOHOL

Avoid consumption of alcohol during treatment with DOTIN 25MG as it can make the feeling of drowsiness worse.

LIVER

DOTIN 25MG is not recommended for use in patients with liver problems. Consult your doctor before taking DOTIN 25MG.

ALLERGY

Do not take DOTIN 25MG if you are allergic to Dosulepin or any other ingredients of this medicine.

HEART DISEASE

DOTIN 25MG is not recommended for use in patients with irregular heartbeat or any other heart problems. Consult your doctor before taking DOTIN 25MG.

OTHERS

DOTIN 25MG is not recommended for use if you:

  • have mania (feeling over excited with unusual behaviour)
  • have glaucoma (increased pressure in eye)
  • have fits (epilepsy)
  • have prostate problems (difficulty in passing urine)

Before taking DOTIN 25MG inform your doctor if you:

  • have any planned surgeries (general or dental surgery)
  • have thyroid problems
  • are intolerant to certain sugars

Use in paediatrics:

DOTIN 25MG is not recommended for use in children and adolescents (under 18 years of age). Consult child’s doctor for advice.

Use in geriatrics:

DOTIN 25MG should be used with caution in elderly patients due to increased risk of side effects such as agitation, confusion and light headedness. Consult your doctor before taking DOTIN 25MG.

INTERACTIONS

A. Drug–Drug Interactions:

Before taking DOTIN 25MG inform your doctor if you are taking any of the following medicines:

  • medicines used to treat depression such as selective serotonin reuptake inhibitor (SSRIs) (Ex. citalopram, fluoxetine) and mono-amine oxidase inhibitor (MAOI) (Ex. isocarboxazid, phenelzine)   
  • medicines used to treat underactive thyroid (Ex. Levothyroxine)
  • medicines used to treat epilepsy (Ex. phenobarbitone), insomnia (Ex. amylobarbitone) and behavioural problems (Ex. methylphenidate)
  • medicine containing an opioid (Ex. codeine, morphine, dihydrocodeine, co-proxamol and co-dydramol) (used to treat pain)
  • medicines used to treat heart problems and asthma (also as cough and cold remedies), sympathomimetic agents (Ex. ephedrine, pseudoephedrine, adrenaline and noradrenaline)
  • medicines used to treat high blood pressure (Ex. guanethidine) and regulate heartbeat (Ex. sotalol)
  • terfenadine, astemizole (used to treat hay fever or allergy)
  • halofantrine (used to treat malaria)

Overdosage:

If you or anyone else accidentally take too much of DOTIN 25MG, consult your doctor immediately or visit the nearby hospital as it may seriously harm you and cause life-threatening problems.

SYNOPSIS

Drug :  

Dosulepin

Pharmacological Category :  

Tricyclic Antidepressants

Therapeutic Indication :   Depression, Anxiety
Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep DOTIN 25MG out of reach of children
  • Store at room temperature

FAQs ABOUT DOTIN 25MG

What is DOTIN 25MG and why is it given?

DOTIN 25MG contains Dosulepin which belongs to the group of medicines called Antidepressants. It is used in the treatment of depression and also helps to reduce the feelings of anxiety, this medicine is used only when other medicines are not suitable.  

Can I stop taking DOTIN 25MG on my own?

You should not stop taking DOTIN 25MG suddenly on your own without the advice of your doctor. Your doctor may gradually withdraw the dose in case of stopping the medicine. If you stop taking DOTIN 25MG suddenly you may experience some withdrawal symptoms like irritability, insomnia and excessive perspiration (sweating).

Is DOTIN 25MG safe to use in pregnant and breast-feeding women?

DOTIN 25MG should be used in pregnant and breast-feeding women only if clearly advised by the doctor. Consult your doctor before taking DOTIN 25MG if you are pregnant or planning to get pregnant or breast-feeding your child.

Can I drive or operate heavy machines after taking DOTIN 25MG?

DOTIN 25MG can cause drowsiness. Therefore, it is not advisable to drive or use machineries and tools until you feel normal again. Consult your doctor for advice before taking DOTIN 25MG.

Can DOTIN 25MG be used in elderly patients?

DOTIN 25MG should be used with caution in elderly patients due to increased risk of side effects such as agitation, confusion and light headedness. Consult your doctor before taking it.

REFERENCES

1. KD. Tripathi. Antidepressant and Antianxiety Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 459.

2. T Nakagawa, K Ukai, S Kubo. Antidepressive effects of the stereoisomer cis-dosulepin hydrochloride. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 1993 [Accessed on 14th June 2022] https://pubmed.ncbi.nlm.nih.gov/8447840/

3. P Zusky, T C Manschreck, C Blanchard, J Rosenbaum, C Elliot, P Lou. Dothiepin hydrochloride: treatment efficacy and safety. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 1986. [Accessed on 14th June 2022] https://pubmed.ncbi.nlm.nih.gov/3531188/

4. Dosulepin. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in September 2022] [Accessed on 14th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Dosulepin#section=Mechanism-of-Action

5. Teva Pharmaceuticals Works Pvt Ltd. Dosulepin. [Revised in March 2021]. [Accessed on 14th June 2022] https://products.tevauk.com/mediafile/id/50662.pdf

6. Teofarma S.r.l. Health Products Regulatory Authority (HPRA). [Revised in July 2020] [Accessed on 14th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/0cc11c1c-a57e-470f-a788-57d351b29341.pdf

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    DOSULEPIN(DOTHIEPIN) 25 mg
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

DOTIN 25mg Tablet 10's

DOTIN 25mg Tablet 10's Mkt: Tasmed India (P) Limited

M.R.P.: Rs.56.62
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