Diziron 25mg Tablet 20'S

Vertigo Rx required

Best Price*  ₹ 122.40
MRP ₹153.00
(Inclusive of all taxes) *20 Tablet(s) in a Strip * Mkt: Glenmark Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

DIZIRON 25MG contains Cinnarizine which belongs to the group of medicines called antihistamines. It is indicated as a maintenance therapy for symptoms of cerebral circulatory disorders (such as dizziness, tinnitus (ringing in the ears), headache, loss of memory, irritability and lack of concentration), disorders of balance (such as vertigo (spinning sensation), dizziness, tinnitus, nystagmus, nausea or vomiting) or peripheral circulatory disorders (such as Raynaud’s phenomenon (reduced blood flow to the fingers), paraesthesia (numbness of hands and feet), cold extremities, nocturnal cramps, acrocyanosis, intermittent claudication, trophic disturbances, trophic and varicose ulcers). It can also be used in the prophylaxis of migraine and motion sickness.

Cinnarizine is a histamine H-1 receptor antagonist with muscarinic anticholinergic, sedative, anti-serotonergic and vasodilator properties. DIZIRON 25MG works by preventing the narrowing of blood vessels, leading to vasodilation and increased blood supply to the targeted organs. Try to take this medicine preferably after meals, as it may reduce the incidence of epigastric distress or gastric irritation. Avoid consumption of alcohol while taking this medicine, as it may increase the risk of side effects.

The most common side effects of this medicine are drowsiness, nausea and weight gain. Avoid traveling, driving or operating any tools or machines while you are feeling drowsy or sleepy. Contact your doctor if any of the symptom bothers you. Before taking this medicine, inform your doctor if you have any liver or kidney disease. DIZIRON 25MG is generally not recommended for use in pregnant or lactating women and children (under 12 years). Consult your doctor before taking.

USES OF DIZIRON 25MG

  • Treats cerebral circulatory disorders (such as dizziness, tinnitus (ringing in the ears), headache, loss of memory, irritability and lack of concentration)
  • Treats disorders of balance (such as vertigo (spinning sensation), dizziness, tinnitus, nystagmus, nausea or vomiting)
  • Treats peripheral circulatory disorders (such as Raynaud’s phenomenon (reduced blood flow to the fingers), paraesthesia (numbness of hands and feet), cold extremities, nocturnal cramps, acrocyanosis, intermittent claudication, trophic disturbances, trophic and varicose ulcers)
  • Prevents migraine and motion sickness

HOW DIZIRON 25MG WORKS

Cinnarizine is a histamine H-1 receptor antagonist with muscarinic anticholinergic, sedative, anti-serotonergic and vasodilator properties. It works by inhibiting the contractions of vascular smooth muscle cells by blocking the activation of voltage-gated calcium channels, leading to vasodilatation of blood vessel and enhanced blood flow in condition such as Raynaud’s phenomenon, paraesthesia, nocturnal cramps, headache and varicose ulcers.

It also mediates neurotransmission in the central nervous system and provides relief from loss of memory, irritability and lack of concentration. It inhibits vestibular sensory nuclei in the inner ear and suppresses disorders of balance (such as vertigo, tinnitus, nystagmus). It also has muscarinic anticholinergic properties which helps to provide relief from motion sickness, nausea and vomiting.

DIRECTIONS FOR USE

Take DIZIRON 25MG as directed by your physician. It should be taken preferably after meals. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF DIZIRON 25MG

COMMON

  • somnolence (sleepiness or drowsiness)
  • nausea
  • weight gain

HOW TO MANAGE SIDE EFFECTS

Nausea:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Weight gain:

Try to exercise more regularly, for e.g., by going for a daily walk or run.

Somnolence:

Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling drowsy or sleepy. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

PREGNANCY

DIZIRON 25MG is considered safe for use by pregnant women. It is advised to consult your doctor before taking this medicine.

BREASTFEEDING

DIZIRON 25MG should be used with caution in breastfeeding mothers. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machines, because this medicine may cause somnolence especially at the start of treatment.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

KIDNEY

DIZIRON 25MG should be taken with caution in patients with kidney problems. Consult your doctor for advice.

LIVER

DIZIRON 25MG should be taken with caution in patients with liver problems. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to cinnarizine.

OTHERS

Before taking DIZIRON 25MG, inform your doctor if you have:

  • Parkinson’s disease
  • porphyria (an inherited blood disorder)
  • low blood pressure
  • fructose and galactose intolerance

INTERACTIONS

Talk to your doctor, if you are taking,

  • medicines used to treat depression (e.g. fluoxetine, sertraline, amitriptyline, imipramine)
  • tranquilisers (used to relax muscles or decrease anxiety) such as diazepam, chlordiazepoxide

SYNOPSIS

Drug :   Cinnarizine
Pharmacological Category :   Antihistamine, Antivertigo, Antiemetic
Therapeutic Indication :   Cerebral circulatory disorders, Peripheral circulatory disorders and Disorders of balance
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT DIZIRON 25MG

Is DIZIRON 25MG safe during lactation?

No. Do not take this medicine if you are breast-feeding due to lack of safety data. Consult your doctor for advice.

Can DIZIRON 25MG cause drowsiness?

Yes. The most common side effect of this medicine is drowsiness. Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling drowsy or sleepy. If the symptom still persists, contact your doctor for advice.

Can we consume alcohol while taking DIZIRON 25MG?

No. Avoid consumption of alcohol while taking this medicine, as it may increase the risk of side effects.

REFERENCES

1. KD. Tripathi. Histamine and Antihistaminics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 168.

2. KD. Tripathi. Antiemetic, Prokinetic and Digestant Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 663-664.

3. Medical Corps, Israel Defense Force. A Double-blind Comparison of Scopolamine with Cinnarizin for Prevention of Simulator Sickness. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2010] [Accessed 30th December 2020] https://clinicaltrials.gov/ct2/show/NCT01198106

4. Milind Vasant Kirtane, Anita Bhandari, Prashant Narang and Ravi Santani. Cinnarizine: A Contemporary Review. NCBI; PMC US National Library of Medicine, National Institute of Health. April 2017. [Accessed 30th December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841794/

5. Foad Taghdiri, Mansoureh Togha, Soodeh Razeghi Jahromi and Farshid Refaeian. Cinnarizine for the prophylaxis of migraine associated vertigo: a retrospective study. NCBI; PMC US National Library of Medicine, National Institute of Health. May 2014. [Accessed 30th December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021030/

6. Aspin Pharma (Pvt) Ltd. Stugeron tablet/Stugeron forte capsule (cinnarizine). Aspin.com. [Revised on October 2017] [Accessed 30th December 2020] http://aspin.com.pk/wp-content/uploads/2020/02/Stugeron-PIL.pdf

7. Janssen-Cilag or Janssen Pharmaceutica NV. Health Products Regulatory Authority (HPRA). [Revised on November 2019] [Accessed 30th December 2020] http://www.hpra.ie/img/uploaded/swedocuments/311b29d1-75be-4d1e-8d70-dcbe034c2f03.pdf

8. Generics [UK] Limited and Gerard Laboratories. Electronic Medicines Compendium (EMC); [Revised on October 2014] [Accessed 30th December 2020] https://www.medicines.org.uk/emc/files/pil.2607.pdf

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    30
    Ingredient
    CINNARIZINE 25MG
    Hsn Code
    30049039
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Diziron 25mg Tablet 20'S

Diziron 25mg Tablet 20'S Mkt: Glenmark Pharmaceuticals Ltd

M.R.P.: Rs.153.00
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