Diprobate S Plus Ointment 30gm
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Introduction About DIPROBATE S PLUS OINTMENT
DIPROBATE S PLUS OINTMENT is a combination of Betamethasone, Salicylic Acid and Zinc Oxide which belongs to the group of medicines called Topical corticosteroids, Keratolytics and Antiseptics respectively. It is topically applied to the skin's surface to reduce the redness and itching brought on by specific skin problems (such as eczema, and psoriasis).
DIPROBATE S PLUS OINTMENT is also used to manage diaper dermatitis, manage minor skin irritations (such as cuts, burns, etc.), and protect against sunburns. Don’t use bandages or plasters, and you shouldn't use a large amount of DIPROBATE S PLUS OINTMENT for a longer period. Avoid smoking; it may lead to a fire.
DIPROBATE S PLUS OINTMENT is not recommended if you have any other skin problems, as they could worsen the condition, particularly rosacea (a condition that affects the face), acne, dermatitis (inflammation of the skin around the lips), genital itching, chicken pox, or other skin conditions.
DIPROBATE S PLUS OINTMENT is not recommended for use by pregnant women unless considered necessary. DIPROBATE S PLUS OINTMENT is not recommended for use by breastfeeding women unless considered necessary. DIPROBATE S PLUS OINTMENT is not recommended for children under 2 years of age.
The most common side effects of taking DIPROBATE S PLUS OINTMENT are burning sensations, irritations or allergic skin reactions, skin redness, itching, excessive dryness, peeling, thinning of your skin, blistering skin, stinging (sharp pain), swelling, skin rashes, and a decrease in skin color. Contact your doctor if any of the symptoms get worse.
Uses Of DIPROBATE S PLUS OINTMENT
- Manage eczema and psoriasis
- Manage diaper dermatitis and minor skin irritations (such as cuts, burns etc)
- Protects from sun burns
How DIPROBATE S PLUS OINTMENT Works
Betamethasone has anti-inflammatory, anti-pruritic, and vasoconstrictive properties; it works by activating natural substances in the skin to reduce swelling, redness, and itching. Salicylic acid acts as a keratolytic by causing the protein keratin (which makes up most of the outer skin structure) to soften.
This helps remove dry, scaly skin easily by helping to loosen it. Zinc oxide acts as an antiseptic, an emollient, and a skin protectant. It works by creating a physical barrier that protects the skin from irritants and improves skin repair.
How to use DIPROBATE S PLUS OINTMENT
Always apply DIPROBATE S PLUS OINTMENT as directed by your physician. Wash your hands before and after use. It is for external use only. Apply a thin layer of this medicine and rub gently on the affected area 2 times a day. Depending on your age, body weight, disease condition, your doctor will fix the correct dose and duration for you.
Side Effects Of DIPROBATE S PLUS OINTMENT
Common
- hair follicles inflammation, abnormal hair growth, decrease in skin colour and allergic reactions of the skin
- dermatitis, (skin inflammation) that develops when the skin reacts to an external factor, such as detergents, and results in red, itchy skin
- blurred vision
Stop taking DIPROBATE S PLUS OINTMENT and contact your doctor immediately if you experience any of the following side effects:
- blurred vision or other visual difficulties
- serious allergic reactions, such as hives, rashes, trouble breathing, and swelling of the tongue, lips, face, or mouth
How To Manage Side Effects
Skin rash Or Itching
Hot water can irritate the skin, so avoid taking hot showers. Do not scratch the affected area. Contact your doctor if the itching does not improve.
Warning & Precautions
Pregnancy
Monitoring requiredDIPROBATE S PLUS OINTMENT is not recommended for use by pregnant women unless considered necessary. Contact your doctor before applying DIPROBATE S PLUS OINTMENT.
Breastfeeding
Monitoring requiredDIPROBATE S PLUS OINTMENT is not recommended for use by breastfeeding women unless considered necessary. Contact your doctor before applying DIPROBATE S PLUS OINTMENT.
Allergy
ContraindicatedDo not receive DIPROBATE S PLUS OINTMENT if you are allergic to betamethasone dipropionate, or salicylic acid or zinc oxide or to other ingredients of this medicine.
Use In Pediatrics
ContraindicatedDIPROBATE S PLUS OINTMENT is not recommended in children under 2 years of age. Contact your doctor before applying DIPROBATE S PLUS OINTMENT.
Others
Inform your doctor before taking DIPROBATE S PLUS OINTMENT if you have or had:
- psoriasis
Interactions
A. Drug-Drug interactions:
Tell your doctor if you have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplement or herbal products.
Overdosage:
If you or your children applied by mistake, consult your doctor immediately or visit the nearby hospital. If it is applied on large area of the body, it can cause hormonal changes and in children it can affect their growth, nausea, vomiting and vertigo (ringing in the ears).
Synopsis
| Drug | : | Betamethasone, Salicylic Acid, Zinc Oxide |
| Pharmacological Category | : | Topical corticosteroids, Keratolytic and Antiseptics |
| Therapeutic Indication | : | Manages eczema and psoriasis, Manages diaper dermatitis and minor skin irritations (such as cuts, burns etc), Protects from sun burns |
| Dosage Forms | : | Cream, Ointment |
More Information
- Keep DIPROBATE S PLUS OINTMENT out of reach of children
- Store DIPROBATE S PLUS OINTMENT below 25°C
FAQs About DIPROBATE S PLUS OINTMENT
Q: What are the uses of DIPROBATE S PLUS OINTMENT?
A: DIPROBATE S PLUS OINTMENT is topically applied to the skin's surface to reduce the redness and itching brought on by specific skin problems (such as eczema and psoriasis). It is also used to manage diaper dermatitis and minor skin irritations (such as cuts, burns, etc.) and used to protect against sunburns.
Q: What are the common side effects of taking DIPROBATE S PLUS OINTMENT?
A: The most common side effects of taking DIPROBATE S PLUS OINTMENT are burning sensations, irritations or allergic skin reactions, skin redness, itching, excessive dryness, peeling, thinning of your skin, blistering skin, stinging (sharp pain), swelling, skin rashes, and a decrease in skin color. Contact your doctor if any of the symptoms get worse.
Q: How does DIPROBATE S PLUS OINTMENT work?
A: Betamethasone has anti-inflammatory, anti-pruritic, and vasoconstrictive properties; it works by activating natural substances in the skin to reduce swelling, redness, and itching. Salicylic acid acts as a keratolytic by causing the protein keratin (which makes up most of the outer skin structure) to soften. This helps remove dry, scaly skin easily by helping to loosen it. Zinc oxide acts as an antiseptic, an emollient, and a skin protectant. It works by creating a physical barrier that protects the skin from irritants and improves skin repair.
Q: Can I use DIPROBATE S PLUS OINTMENT with children?
A: DIPROBATE S PLUS OINTMENT is not recommended for children under 2 years of age. Contact your doctor before applying DIPROBATE S PLUS OINTMENT.
Q: Can I use DIPROBATE S PLUS OINTMENT during pregnancy?
A: DIPROBATE S PLUS OINTMENT is not recommended for pregnant women unless considered necessary. Contact your doctor before applying DIPROBATE S PLUS OINTMENT.
References
1. Craig Burkhart, Dean Morrell, and Lowell Goldsmith. Dermatological Pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1808.
2. KD Tripathi. Drugs Acting on Skin and Mucous Membranes. Seventh edition. 2013. Page - 889, 895.
3. Dirk B. Robertson and Howard I. Maibach. Dermatologic Pharmacology. Basic and Clinical Pharmacology. 14th Edition. New York McGarw Hill Education 2018. Page – 1082.
4. Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clinical, Cosmetic and Investigational Dermatology. Aug 2015. [Accessed on 25th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554394/
5. Schering-Plough Labo NV. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 25th August 2022] https://www.medicines.org.uk/emc/files/pil.1450.pdf
6. Schering-Plough Labo NV. Health Products Regulatory Authority (HPRA). [Revised in December 2013] [Accessed on 25th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/2141458.PA1286_029_002.3a4049fa-53f3-4f18-a9a3-c2a8e6383c64.000001Product%20Leaflet%20Approved.pdf.140219.pdf
7. Bethesda (MD). Salicylic Acid. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 25th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Salicylic-acid
8. Thornton & Ross Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2019] [Accessed on 25th August 2022] https://www.medicines.org.uk/emc/files/pil.4961.pdf
9. E. Fougera & Co. Betamethasone Dipropionate. [Revised in February 1, 2022] [Accessed on 25th August 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=97dde5f5-a865-4af2-b562-8da72c8475f3
10. Dynarex Corporation. Zinc Oxide. [Revised in April 2017] [Accessed on 25th August 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9b4e0661-5d0a-4002-bc66-b1246ec6b858
11. Salicylic Acid Ointment. Drugs.com. [Accessed on 25th August 2022] https://www.drugs.com/pro/salicylic-acid-ointment.html
12. Zinc oxide topical. Drugs.com. [Accessed on 25th August 2022] https://www.drugs.com/mtm/zinc-oxide-topical.html
13. MedIndia. Zinc oxide. [Revised in January 2016] [Accessed on 17th August 2022] https://www.medindia.net/doctors/drug_information/zinc_oxide.htm
14. MedIndia. Betzee -S Cream. [Revised in January 2016] [Accessed on 17th August 2022] https://www.medindia.net/doctors/drug_information/zinc_oxide.htm
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