DERIVA MS Gel 15gm

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Drug Information

What is Adapalene used for?

Adapalene gel is used on the face, chest or back for treatment of mild to moderate acne, where there are blackheads, spots and pimples.

Adapalene may also be prescribed for other conditions as determined by your doctor.

How does Adapalene work?

  • Adapalene is a retinoid-like compound which
    • penetrates deep inside the skin pores and prevents the build-up of dead skin and sebum that leads to acne formation;
    • blocks the hardening processes of the outer skin layer which helps in shedding of old hardened skin cells, thereby promoting growth of new skin cells;
    • blocks the inflammatory reaction, which help to reduce soreness and irritation of skin.

How to use Adapalene?

  • The application of topical gel of Adapalene depends on medical condition of an individual. Apply Adapalene gel as prescribed by your doctor.
  • Adapalene gel is for EXTERNAL USE ONLY.
  • Apply Adapalene at night before going to bed. Wash the area to be applied with water thoroughly. Make sure the skin is clean and dry before applying the medicine.
  • Take a thin film of Adapalene gel on your fingertip and apply on the affected area gently.
  • Wash your hands properly after applying Adapalene gel.
  • Avoid application of Adapalene into eyes or lips.
  • Do not apply Adapalene on cuts, abrasion or eczematous skin.
  • Adapalene is not to be used in adolescent and children below 12 years of age.
  • Do not discontinue Adapalene without doctor’s advice.
  • If you miss a dose of Adapalene gel, please apply it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed dose.

What should you do when you have used more Adapalene?

If you have used more Adapalene gel than advised by your doctor or have accidentally swallowed Adapalene gel, please contact your doctor immediately.

Symptoms of excess use of Adapalene on skin are:

  • Skin irritation
  • Redness of skin
  • Peeling of skin
  • Discomfort on skin

 What are the drugs that interact with Adapalene?

Drugs that interact with Adapalene:

  • Aromatic and Alcoholic agents
  • Astringents
  • Peeling agents
  • Skin abrasive cleaners
  • Skin drying agents

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Adapalene?

Most common side effects of Adapalene are:

  • Dry skin
  • Irritation of the skin
  • Burning sensation of the skin
  • Redness of the skin (erythema)

Please stop application of Adapalene gel and contact your physician immediately if you have

  • irritant contact dermatitis (blistering, cracking skin, swelling, stiffness of skin, ulcers on skin, sore skin forming crust);
  • skin discomfort, pain and swelling of skin;
  • sunburn;
  • itching of the skin;
  • peeling skin;
  • irritation, redness, itching or swelling of the eyelids;
  • flare up of acne.

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Adapalene?

  • Seek doctor’s advice before taking any other drug or herbal products while on Adapalene.
  • If you are using other medications for acne like benzoyl peroxide, erythromycin or clindamycin, they may be applied in the morning and Adapalene may be applied at night time.
  • If you have a hypersensitivity skin reaction, please stop using Adapalene gel immediately.
  • If you have applied Adapalene gel by mistake into eyes, mouth, nostrils or mucous membrane, wash immediately with warm water.
  • Adapalene has propylene glycol (E1520) as excipient which may cause skin irritation and parahydroxybezoate (E218), which may cause allergic reactions.

You are advised not to take Adapalene if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.
  • you have severe form of acne

What should you tell your doctor before taking Adapalene?

Tell your doctor if

  • you are allergic to Adapalene or to any ingredients of this medicine.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you are planning a surgery or any procedure.
  • you are pregnant or trying to conceive or are breastfeeding.

Frequently asked questions about Adapalene

  • How should Adapalene be stored?
  • Adapalene gel should be stored below 25° C in a cool, dry place. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

  • Should I follow any special dietary instructions while using Adapalene gel?
  • There are no dietary restrictions if you are taking Adapalene.

  • How long will it take for Adapalene to work?
  • It may take up to 3 months for Adapalene gel to work. Please consult your doctor for more information.

  • Can I go out in the sun while applying Adapalene?
  • If possible, limit your sun exposure. If you are going outside, apply sunscreen as advised by your doctor. If you are using Adapalene gel in the morning, then let is dry first and then apply the sunscreen.


    The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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