Deritard Injection 2ml

Introduction About DERITARD INJECTION

DERITARD INJECTION contains a combination of Etofylline and Theophylline which belongs to the group of medicines called Bronchodilators. It is used in the management of asthma (in which airways narrow and swell and may produce extra mucus, coughing and shortness of breath), chronic bronchitis (inflammation of the lining of bronchial tubes, which carry air to and from lungs causing cough and thick mucus), and chronic obstructive pulmonary disorder.

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Symptoms include breathing difficulty, cough, mucus (sputum) production and wheezing.

Before receiving DERITARD INJECTION inform your doctor if you have porphyria, liver, kidney, heart, lung, thyroid problems, glaucoma, have fever, low blood oxygen, poor circulation, fits, are a smoker, have peptic ulcer, are diabetic. Avoid consumption of alcohol during this management.

Inform your doctor if you are pregnant or breastfeeding before receiving DERITARD INJECTION. DERITARD INJECTION is not recommended for use in children below 6 months of age. It should be used with caution in elderly patients above 55 years of age. The most common side effects of receiving DERITARD INJECTION are nausea, vomiting, headache, restlessness, dizziness. Consult your doctor if symptoms do not show any improvement.

Uses Of DERITARD INJECTION

To manage:

• Asthma
• Chronic Bronchitis
• Chronic Obstructive Pulmonary Disease (COPD)

How DERITARD INJECTION Works

DERITARD INJECTION works by relaxing the smooth muscles in the airway in which etofylline works by dilating and relaxing the airway muscles and theophylline relaxes the smooth muscles located in the bronchial airways and pulmonary blood vessels, reduces the airway responsiveness to allergens thereby reducing inflammation.

How to use DERITARD INJECTION

DERITARD INJECTION will be given to you only by a doctor or a nurse into the veins (intravenously). Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.

Side Effects Of DERITARD INJECTION

How To Manage Side Effects

Diarrhea

Drink lots of or fruit juice to keep yourself hydrated. If the symptom does not show improvement, consult your doctor.

Headache

Avoid bright lights, drink more water, and take rest. If the symptom does not show improvement, consult your doctor.

Nausea And Vomiting

Stick to simple meals. Avoid eating rich or spicy food. If the symptom does not show improvement, consult your doctor.

Stomach Pain

Try to rest and relax and have smaller and frequent meals. Keep a heat pad on stomach. If the symptom does not show improvement, consult your doctor.

Warning & Precautions

Pregnancy

Monitoring required

DERITARD INJECTION is not recommended for use in pregnant women or women planning to be pregnant uncles clearly necessary. Consult your doctor before receiving DERITARD INJECTION.

Breastfeeding

Contraindicated

DERITARD INJECTION is not recommended for use in breastfeeding women as it is excreted in breastmilk. Consult your doctor before receiving it.

Driving and Using Machines

Safe

DERITARD INJECTION has no or negligible effect on your ability to drive or use machines. Do not drive or use machines in case of adverse effects.

Alcohol

Consult your doctor

Do not consume alcohol while receiving DERITARD INJECTION as it can alter the way this medicine works.

Kidney

Use with Caution

DERITARD INJECTION should be used with caution in patients with kidney disease. Consult your doctor before receiving it.

Liver

Use with Caution

DERITARD INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving it.

Allergy

Contraindicated

Do not receive DERITARD INJECTION if you are allergic to Etofylline or Theophylline or any other ingredients of this medicine.

Lungs

Use with Caution

DERITARD INJECTION should be used with caution in patients with chronic bronchitis or lung failure. Consult your doctor before receiving it.

Heart Disease

Use with Caution

DERITARD INJECTION should be used with caution in patients with heart disease, high blood pressure, heart failure or any other heart problems. Consult your doctor before receiving it.

Use In Pediatrics

Contraindicated

DERITARD INJECTION is not recommended for use in children below 6 months of age. Consult your doctor before receiving it.

Use In Geriatrics

Use with Caution

DERITARD INJECTION should be used with caution in elderly patients above 55 years of age. Consult your doctor before receiving it.

Interactions

A. Drug-Drug interactions:

Before receiving DERITARD INJECTION, inform your doctor if you are taking any of the following medicine:

• certain other medicines to manage asthma or breathing conditions that contain theophylline, aminophylline, salbutamol, terbutaline, zafirlukast, or salmeterol, steroids (Ex. prednisolone, hydrocortisone)
• oral contraceptives
• St John’s Wort, fluvoxamine or lithium (for depression)
• carbamazepine or phenytoin (for seizures, fits or convulsions)
• adenosine, diltiazem, isoprenaline, mexiletine, propafenone, propranolol, verapamil or beta blockers, regadenoson or dipyridamol (for high blood pressure and other heart problems)
• sulphinpyrazone or allopurinol (for gout)
• carbimazole (for problems of thyroid gland)
• cimetidine or nizatidine (to manage stomach ulcers, indigestion or heartburn)
• antibiotics (Ex. ciprofloxacin, clarithromycin, erythromycin, enoxacin)
• fluconazole (manage fungal infections)
• rifampicin or isoniazid (manage tuberculosis)
• ritonavir to manage HIV
• medicines to thin your blood (Ex. warfarin)
• disulfiram (manages alcoholism)
• you have recently had, or are going to have a flu injection

B. Drug-Food interaction:

• avoid caffeinated drinks during this management

Overdosage:

DERITARD INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms like thirsty, have ringing in your ears or feel palpitations.

Synopsis

More Information

• Keep DERITARD INJECTION out of reach from children
• Do not store above 25°C

FAQs About DERITARD INJECTION

Q: What is DERITARD INJECTION used for?

A: DERITARD INJECTION is used in the management of asthma, chronic bronchitis, and chronic obstructive pulmonary disorder. Consult your doctor for more information.

Q: Can DERITARD INJECTION be received pregnant women?

A: DERITARD INJECTIONis not recommended for use in pregnant women or women planning to be pregnant uncles clearly necessary. Consult your doctor before receiving it.

Q: Can DERITARD INJECTION be used in patients with heart problems?

A: DERITARD INJECTIONshould be used with caution in patients with heart disease, high blood pressure, heart failure or any other heart problems. Consult your doctor before receiving it.

Q: Can I consume alcohol while receiving DERITARD INJECTION?

A: Do not consume alcohol while receiving DERITARD INJECTION as it can alter the way this medicine works. Consult your doctor if you are addicted to alcohol.

Q: How does DERITARD INJECTION work?

A: DERITARD INJECTION works by relaxing the smooth muscles in the airway in which etofylline works by dilating and relaxing the airway muscles and theophylline relaxes the smooth muscles located in the bronchial airways and pulmonary blood vessels, reduces the airway responsiveness to allergens thereby reducing inflammation.

References

1. KD Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Eighth Edition. 2019. Page –243-247.

2. Peter J. Barnes. Theophylline. [Accessed on 9th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033977/

3. J Zuidema, J Verhoeven, F W Merkus. Pharmacokinetics of etofylline after intravenous and oral administration to humans. [Accessed on 9th August 2022] https://pubmed.ncbi.nlm.nih.gov/7263108/

4. Siegfried Hameln GmbH. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 9th August 2022]. https://www.medicines.org.uk/emc/files/pil.6299.pdf, https://www.medicines.org.uk/emc/product/6299/smpc

5. Pubchem. Etofylline. [Revised on August 2022] [Accessed on 9th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/etofylline

6. NIH. Etofylline. [Accessed on 9th August 2021] https://drugs.ncats.io/drug/L164909TBI

7. Theophylline. Mayoclinic.[Revised on February 2022] [Accessed on 9th August 2022] https://www.mayoclinic.org/drugs-supplements/theophylline-intravenous-route/description/drg-20073548

8. Etofylline, Theophylline. Mayoclinic. [Revised in April 2020] [Accessed on 9th August 2022] https://www.mayoclinic.org/diseases-conditions/copd/symptoms-causes/syc-20353679

Useful Diagnostic Tests

• Lung function test
• Chest X-ray
• CT scan

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 13 Feb 2023 | 01:29 PM(IST)