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What is DEPOTEX 40MG?
- DEPOTEX 40MG contains Methylprednisolone which belongs to corticosteroids
What DEPOTEX 40MG is used for?
It is used to treat inflammatory or allergic conditions affecting the:
- brain caused by a tumour or meningitis
- bowel and gut e.g. ‘Crohn’s disease’ and ‘ulcerative colitis’
- lungs caused by asthma, severe allergy or hypersensitivity, tuberculosis or breathing in (aspirating) vomit or stomach contents
- skin e.g. Stevens-Johnson Syndrome
It is also used following the organ transplant surgeries, flareups of the symptoms of multiple sclerosis or other stressful conditions
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Pregnancy & Breast Feeding
Children & Adolescents
Driving & Using Machines
Talk to your Doctor if you
- are allergic to DEPOTEX 40MG or any other ingredients of this medicine
- have any fungal infection (such as thrush)
- have recently had, or are about to have any vaccination
- are suffering from, or receiving treatment for malaria
- are suffering from a head injury or stroke
- have chickenpox, measles, shingles or a herpes eye infection
- have heart failure
- have worm infestation (e.g. threadworm)
- have severe depression or manic depression (bipolar disorder)
- have delusions, hallucinations or disorganized speech
- have diabetes
- have epilepsy, fits or seizures
- have glaucoma
- have recently suffered a heart problem, including heart failure or infections
- have hypertension (high blood pressure)
- have hypothyroidism (an under-active thyroid)
- have joint infection
- have kaposi’s sarcoma (a type of skin cancer)
- have kidney or liver disease
- have muscle problems (pain or weakness)
- have myasthenia gravis (a condition causing tired and weak muscles)
- have osteoporosis (brittle bones)
- have skin abscess
- have stomach ulcer, diverticulitis (inflammation of the bowel wall) or other serious stomach or intestinal problems
- have thrombophlebitis – vein problems due to thrombosis (clots in the veins) resulting in phlebitis (red, swollen and tender veins)
- have tuberculosis (TB)
- have unusual stress
- have cushing’s disease (condition caused by an excess of cortisol hormone in your body)
- have acute pancreatitis (inflammation of the pancreas)
- If you are pregnant, think you might be pregnant or trying to become pregnant as this medicine could slow the baby’s growth
- Cataracts have been observed in infants born to mothers undergoing long-term treatment with DEPOTEX 40MG during pregnancy
- Tell your doctor if you are breastfeeding as small amounts of DEPOTEX 40MG may get into breast milk
Tell your doctor if you are taking,
- acetazolamide (used to treat glaucoma, epilepsy and water retention)
- aminoglutethimide or cyclophosphamide (used for treating cancer)
- anticoagulants e.g. acenococoumarol, phenindione and warfarin
- anticholinesterases e.g. distigmine, neostigmine (used to treat myasthenia gravis)
- antibiotics e.g. erythromycin, clarithromycin or troleandomycin (used to treat bacterial infection)
- antidiabetics (used to treat high blood sugar)
- antihypertensives (used to treat high blood pressure)
- aprepitant, fosaprepitant (used to prevent nausea and vomiting)
- non-steroidal anti-inflammatory drugs (also called NSAIDs) e.g: aspirin, ibuprofen, naproxen, diclofenac (used to treat mild to moderate pain)
- barbiturates, carbamazepine, phenytoin and primidone (used to treat epilepsy)
- carbenoxolone, cimetidine (used for heartburn and acid indigestion)
- ciclosporin (used to treat severe rheumatoid arthritis, severe psoriasis, organ or bone marrow transplant)
- digoxin (used for heart failure, irregular heart beat)
- diltiazem, mibefradil (used for heart problems or high blood pressure)
- ethinylestradiol, norethisterone (oral contraceptive)
- isoniazid (used to treat bacterial infections)
- ketoconazole, itraconazole (used to treat fungal infections)
- mifepristone (used for the medical termination of pregnancy)
- neuromuscular blocking agents e.g. pancuronium, vercuronium (used in some surgical procedures)
- potassium depleting agents e.g. diuretics (used to treat heart problems)
- amphotericin B, xanthenes or beta2-agonists (used to treat asthma)
- rifampicin, rifabutin (used to treat tuberculosis) (TB)
- tacrolimus (used following an organ transplant to prevent rejection of the organ)
- ritonavir, cobicistat (used to treat HIV)
- live vaccines
- DEPOTEX 40MG must only be given by a doctor or nurse
- The injection will be given into a vein (intravenous) or into a muscle (intramuscular)
- Usually the first dose is given into a vein, especially in an emergency
- It will be given slowly over at least 5 minutes
If you take more DEPOTEX 40MG
- Your doctor or nurse will give you DEPOTEX 40MG, so it is unlikely that you will receive too much. If you think you have been given too much, tell your doctor or nurse
If you forget to take DEPOTEX 40MG
- If you have forgotten to take your injection take them as soon as possible on the same day. Do not take a double dose
If you stop taking DEPOTEX 40MG
- Do not stop taking injection without talking to your doctor first
Like all medicines, this medicine can cause side effects, although not everybody gets them.
- allergic reactions such as skin rash, swelling of the face or wheezing and difficulty breathing
- pancreatitis, stomach pain spreading to your back, possibly accompanied by vomiting, shock and loss of consciousness
- burst or bleeding ulcers
- infections symptoms might include a raised temperature and feeling unwell
- pulmonary embolus (blood clots in the lung), symptoms include sudden sharp chest pain, breathlessness and coughing up blood
- raised pressure within the skull of children (pseudotumor cerebri) symptoms of which are headaches with vomiting, lack of energy and drowsiness. This side-effect usually occurs after treatment is stopped
- thrombophlebitis (blood clots or thrombosis in a leg vein), symptoms of which include painful swollen, red and tender veins
- high blood pressure, symptoms of which are headaches, or generally feeling unwell swelling and high blood pressure, caused by increased levels of water and salt content
- ulcers
- cataracts (indicated by failing eyesight)
- poor wound healing slowing of normal growth in infants, children and adolescents which may be permanent
- round or moon-shaped face (cushingoid facies)
- increased susceptibility to infection
- brittle bones (bones break easily)
- muscle weakness
- steroids including methylprednisolone can cause serious health problems
- feeling depressed
- feeling high (mania), or moods that go up and down
- feeling anxious, having problems sleeping, difficulty in thinking or being confused and losing your memory
- feeling, seeing or hearing thing which do not exist having strange and frightening thoughts, changing how you act or having feelings of being alone
- acne
- bruising
- thinning of skin (skin atrophy)
- Keep this medicine out of reach of children
- Do not use this medicine after the expiry date
- Store at room temperature (15-25ºC)
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DISCLAIMER
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
