DAPAGLYN 10 Tablet 15's

Diabetes Rx required

Best Price* ₹ 224.40 MRP ₹ 280.50
(Inclusive of all taxes) *15 Tablet(s) in a Strip * Mkt: Cadila Healthcare Ltd (Zydus) * Country of Origin: India * Delivery charges if applicable will be applied at checkout

Check Availability & Expiry

PINCODE:


INTRODUCTION

DAPAGLYN 10 contains Dapagliflozin which belongs to the group of medicines called Antidiabetics. It is used to treat type 2 diabetes when cannot be controlled with diet and exercise (in adults and children aged 10 years and above), heart failure (condition in which the heart is unable to pump an adequate supply of blood to the body) and chronic kidney disease (condition in which the kidneys are damaged and cannot filter blood properly) in adults. Type 2 diabetes is a chronic or life-long condition in which cells of the body fail to respond to insulin and in later stages, the body even fails to produce enough amount of insulin. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.

Dapagliflozin works by blocking the SGLT2 (sodium-glucose co-transporter-2) protein in kidney causing elimination of blood sugar (glucose), salt (sodium) and water in the form of urine. These effects on the kidneys may also help improve your heart's ability to pump blood to the body and thus reduces the risk of cardiovascular diseases. Your doctor may recommend you to follow diet and exercise better results while taking DAPAGLYN 10.

Before taking DAPAGLYN 10, inform your doctor if you have or ever had type 1 diabetes, kidney problems, liver problems, and infections of the urinary tract. DAPAGLYN 10 is generally not recommended for use among pregnant and breastfeeding women. Avoid consumption of alcohol while taking DAPAGLYN 10 due to increased risk of developing diabetic ketoacidosis (high levels of ketone bodies in blood due to diabetic complication). It should be used with caution in elderly patients (aged 65 years and above). The most common side effects of taking DAPAGLYN 10 are genital infection (thrush) of your penis or vagina, back pain, passing more urine, dizziness, and rash. Contact your physician if any of the symptoms worsen.

USES OF DAPAGLYN 10

Treats:

  • type 2 diabetes (in adults and children aged 10 years and older)
  • heart failure in adults
  • chronic kidney disease in adults

HOW DAPAGLYN 10 WORKS

DAPAGLYN 10 works by blocking the SGLT2 (sodium-glucose co-transporter-2) protein in kidney causing elimination of blood sugar (glucose), salt (sodium) and water in the form of urine. These effects on the kidneys may also help improve your heart's ability to pump blood to the body and thus reduces the risk of cardiovascular diseases.

DIRECTIONS FOR USE

Take DAPAGLYN 10 as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DAPAGLYN 10

COMMON

  • genital infection (thrush) of your penis or vagina (signs may include itching, irritation, unusual discharge, odor)
  • back pain
  • increased urine frequency or need to urinate
  • dizziness
  • rash

UNCOMMON

  • dehydration (loss of too much fluid from the body) (signs may include a very dry or sticky mouth, passing slight or no urine, or fast heartbeat)
  • thirst
  • constipation
  • dry mouth
  • increased urine frequency at nighttime
  • weight decreased

RARE

Stop taking DAPAGLYN 10 and contact your doctor immediately if you experience any of the following side effects:

  • angioedema (signs include swelling of the face, tongue, or throat, difficulties swallowing, hives, and breathing problems)
  • diabetic ketoacidosis (signs include increased levels of ketone bodies in urine or blood, nausea or vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to breath, a sweet or metallic taste in the mouth or a different odor to urine or sweat, and rapid weight loss)
  • necrotizing fasciitis of the perineum or fournier’s gangrene (a serious soft tissue infection of the genitals or the area between the genitals and the anus)
  • urinary tract infection (signs include fever and/or chills, burning sensation when passing urine, pain in the back or side)
  • hypoglycemia (low blood sugar levels) (signs include shaking, sweating, feeling very anxious, fast heartbeat, feeling hungry, headache, change in vision, a change in mood, or feeling confused)

HOW TO MANAGE SIDE EFFECTS

Constipation:

Eat plenty of fibre-rich foods such as fresh fruits, vegetables, and cereals, and drink plenty of water. Exercise more regularly. Contact your doctor if constipation do not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness did not improve.

Dry mouth:

Try to drink plenty of cold water. Sip on cold unsweetened drinks and use lip balm if your lips are dry. Try to brush your teeth twice a day and use mouthwash. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

DAPAGLYN 10 is not recommended for use in second and third trimesters of pregnancy and stop taking the medicine if you become pregnant. Consult your doctor before taking DAPAGLYN 10.

BREASTFEEDING

DAPAGLYN 10 is not recommended for use in breastfeeding women as it is not known whether it may pass through breast milk. Consult your doctor before taking DAPAGLYN 10.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy after taking DAPAGLYN 10.

ALCOHOL

Avoid consumption of alcohol while taking DAPAGLYN 10 due to increased risk of developing diabetic ketoacidosis.

KIDNEY

DAPAGLYN 10 should be taken with caution in patients having kidney problems with diabetes. Consult your doctor before taking DAPAGLYN 10.

LIVER

DAPAGLYN 10 should be taken with caution in patients with liver disease. Consult your doctor before taking DAPAGLYN 10.

ALLERGY

Do not take DAPAGLYN 10 if you are allergic to dapagliflozin or any of the other ingredients of this medicine.

OTHERS

Before taking DAPAGLYN 10, inform your doctor if you:

  • have type 1 diabetes
  • have diabetic ketoacidosis
  • have low blood pressure
  • have very high levels of sugar in the blood which may make you dehydrated (lose too much body fluid)
  • have fever, nausea, vomiting unable to eat or drink (these conditions causes dehydration)
  • have urinary tract infections
  • prolonged fasting
  • had major surgery
  • have serious illness
  • are due for your urine test
  • have intolerance to lactose (milk sugar)

Use in pediatrics:

DAPAGLYN 10 should be used with caution in children aged 10 years and older for the treatment of type 2 diabetes mellitus and it is not recommended for use in children and adolescents under 18 years of age for the treatment of heart failure or chronic kidney disease. Contact child’s doctor for advice.

Use in geriatrics:

DAPAGLYN 10 should be used with caution in elderly patients aged 65 years and above. Contact your doctor before taking DAPAGLYN 10.

INTERACTIONS

A. Drug-Drug interactions:

Before taking DAPAGLYN 10, inform your doctor if you are taking any of the following medicines used to:

  • remove water from the body (diuretics, Ex. furosemide)
  • lower the amount of sugar in the blood (Ex. insulin or sulphonylureas like glimepiride, gliclazide)

Overdosage:

If you or anyone else accidentally take too much of DAPAGLYN 10, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   Dapagliflozin
Pharmacological Category :   Antidiabetic Agent
Therapeutic Indication :   Type 2 diabetes, heart failure and chronic kidney disease
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep DAPAGLYN 10 out of reach of children
  • Store at a room temperature

FAQs ABOUT DAPAGLYN 10

What is DAPAGLYN 10 used for?

DAPAGLYN 10 is used to treat type 2 diabetes when cannot be controlled with diet and exercise (in adults and children aged 10 years and above), heart failure and chronic kidney disease in adults.

Can I stop taking DAPAGLYN 10 on my own?

Do not stop taking DAPAGLYN 10 on your own, without consulting your physician. Sudden discontinuation of DAPAGLYN 10 can make diabetes worse and increases the risk of other complications. Inform your doctor if there is no considerable improvement in your condition.

Can DAPAGLYN 10 affects pregnancy?

DAPAGLYN 10 is generally not recommended for use in second and third trimesters of pregnancy and stop taking the medicine if you become pregnant. Consult your doctor before taking DAPAGLYN 10 if you are planning for pregnancy.

Can DAPAGLYN 10 cause urinary tract infection?

Yes, using DAPAGLYN 10 may cause urinary tract infections in few peoples. Not every individual gets the side effect, so it is always better to practice good hygiene. Contact your doctor before taking DAPAGLYN 10.

Is DAPAGLYN 10 safe to use in children?

DAPAGLYN 10 should be used with caution in children aged 10 years and older for the treatment of type 2 diabetes mellitus and it is not recommended for use in children and adolescents under 18 years of age for the treatment of heart failure or chronic kidney disease. Consult child’s doctor for advice regarding the use of DAPAGLYN 10.

What to do if I forget to take DAPAGLYN 10?

If you forget to take a dose of DAPAGLYN 10, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for a forgotten dose.

How does DAPAGLYN 10 work?

DAPAGLYN 10 works by blocking the SGLT2 (sodium-glucose co-transporter-2) protein in kidney causing elimination of blood sugar (glucose), salt (sodium) and water in the form of urine. These effects on the kidneys may also help improve your heart's ability to pump blood to the body and thus reduces the risk of cardiovascular diseases.

REFERENCES

1. Alvin C. Powers and David D’Alessio. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia, Goodman & Gilman’s: The Pharmacological basics of Therapeutics, 13th Edition. New York McGraw Hill Medical 2018. Page – 863 - 886.

2. Sohita Dhillon. Dapagliflozin: A Review in Type 2 Diabetes. National Institute of Health. NLM. National Centre for Biotechnology Information. PMC. Pubmed Central. June 2019 [Accessed on 9th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879440/

3. Sarah L. Anderson. Dapagliflozin efficacy and safety: a perspective review. National Institute of Health. NLM. National Centre for Biotechnology Information. PMC. Pubmed Central. December 2014 [Accessed on 9th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232499/

4. John J.V. McMurray, Scott D. Solomon, Silvio E. Inzucchi, Lars Kober, Mikhail N. Kosiborod, Felipe A. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. The New England Journal of Medicine. November 2019 [Accessed on 9th June 2022] https://www.nejm.org/doi/full/10.1056/NEJMoa1911303

5. Feng, Miao MM, Lv, Haihong PhD, Xu, Xia MM, Wang, Jue MM, Lyu, Wenyi MA, Fu, Songbo MM, Li., Sheyu. Efficacy and safety of dapagliflozin as monotherapy in patients with type 2 diabetes mellitus. Journal of Medicines. July 2019 [Accessed on 9th June 2022] https://journals.lww.com/md-journal/fulltext/2019/07260/efficacy_and_safety_of_dapagliflozin_as.65.aspx

6. AstraZeneca UK Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 9th June 2022] https://www.medicines.org.uk/emc/files/pil.7607.pdf

USEFUL DIAGNOSTIC TESTS

  • Glucose - Fasting Blood
  • Glucose - Postprandial Blood
  • Glycosylated Hemoglobin

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    25 g
    Ingredient
    DAPAGLIFLOZIN 10 mg
    Hsn Code
    30049099
ALTERNATE BRANDS View All
DAXIGA 10 Tablet 10's
Prescription Diabetes Rx required
Rs.44.00
DGSON 10 Tablet 10's
Prescription Diabetes Rx required
Rs.45.00
DAPAGAIN 10 Tablet 15's
Prescription Diabetes Rx required
Rs.88.50
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

DAPAGLYN 10 Tablet 15's

DAPAGLYN 10 Tablet 15's Mkt: Cadila Healthcare Ltd (Zydus)

M.R.P.: Rs.280.50
Copyright© 2022. All Rights Reserved.