Abbott India Ltd

Cremaffin Plus Sugar Free Refreshing Flavour Syrup 225ml

Constipation
MRP ₹270.26 (Inclusive of all taxes)
New Reduced MRP as per revised GST benefit.
Deliver to

    Netmeds First Membership

    Starting at just ₹[] for 3 months.
    View Plans

    Introduction About CREMAFFIN PLUS SYRUP

    What is Cremaffin Plus Sugar Free Syrup?

    Cremaffin Plus Sugar Free Syrup is specially formulated to support smooth digestion with a refreshing flavour. It is sugar free, making it suitable for those seeking a digestion aid without added sugars.

    Cremaffin Plus Sugar Free Syrup is designed for occasional use to support comfortable digestive rhythm. Follow the dosage instructions on the label or as advised by a healthcare provider. It is important to use as directed and consult a healthcare professional for prolonged symptoms or specific health concerns.

    Who May Consider Cremaffin Plus Syrup?

    It is suitable for individuals seeking relief from occasional irregular bowel function while avoiding added sugars. This syrup can be considered as part of a balanced dietary routine aimed at digestive ease.

    Before starting Cremaffin Plus Sugar Free Syrup, your doctor might ask you to take some diagnostic tests. It is not recommended for use in patients having kidney diseases, intestinal obstructions and undiagnosed abdominal pain.

    Cremaffin Plus Sugar Free Syrup should be used with caution in pregnant and breast-feeding women. It is not recommended for use in children. The most common side effects of using Cremaffin Plus Sugar Free Syrup are diarrhoea, nausea, vomiting, muscle weakness, very dry mouth, extreme thirst, rectal bleeding, abdominal cramps, dizziness, and gastrointestinal disturbances. Consult your doctor if any of the above side effects worsen or persists for a longer duration.

    Key Composition

    • Sennosides: Contributes to stimulating natural bowel movement
    • Docusate Sodium: Helps soften stools gently for easy passage
    • Refreshing Flavour: Provides a pleasant taste experience for easier intake

    Uses Of CREMAFFIN PLUS SYRUP

    Used for short-term management of constipation associated with:

    • anal fissure
    • piles
    • hernia
    • pre/post-operative conditions

    Benefits of CREMAFFIN PLUS SYRUP

    • 225ml bottle size for convenient dosing
    • Sugar free formula supporting diabetic-friendly consumption
    • Refreshing flavour to enhance user experience

    How Cremaffin Plus Syrup Supports Digestion

    • Cremaffin Plus Syrup supports digestion and eases constipation through the combined action of its three key ingredients: liquid paraffin, milk of magnesia, and sodium picosulphate
    • By combining stool softening, water retention, and enhanced motility, Cremaffin Plus Syrup gently supports overall digestive function and alleviates discomfort related to infrequent or difficult bowel movements
    • Cremaffin Plus Sugar Free Syrup supports digestion by softening stools, increasing water content in the intestines, and stimulating bowel movements in a synergistic manner. This multi-mechanistic approach provides gentle, effective relief from occasional constipation while maintaining patient safety and comfort

    How CREMAFFIN PLUS SYRUP Works

    Cremaffin Plus Sugar Free Syrup helps in managing constipation and relieving acidity.

    • Liquid Paraffin: Acts as a lubricant by coating the stool and intestinal lining, making stool softer and easier to pass without causing irritation.
    • Milk of Magnesia (Magnesium Hydroxide): Draws water into the intestines through osmotic effect, increasing the volume of stool and stimulating bowel movement.
    • Sodium Picosulphate: A stimulant laxative that is activated by bacteria in the gut, increasing the motility of the gastrointestinal tract and encouraging evacuation

    How It Supports Gentle Bowel Evacuation

    • Cremaffin Plus Syrup supports gentle bowel evacuation through a synergistic action of its active ingredients
    • These mechanisms provide a balanced, effective relief by softening stool, lubricating the bowels, and enhancing intestinal motility for comfortable and timely bowel movements
    • Patients are advised to take the syrup as directed by a healthcare professional, typically at bedtime, and follow dosage instructions carefully. Maintaining adequate hydration alongside its use is important to support bowel function and manage dehydration. This multi-mechanistic formula ensures a gentle yet effective bowel evacuation process aimed at enhancing patient comfort and digestive well-being

    How to use CREMAFFIN PLUS SYRUP

    Take Cremaffin Plus Sugar Free Syrup as advised by your physician. Shake well before use. Your doctor will decide the right dose and duration for you depending upon your age, body weight and disease condition.

    1. Recommended Dosage and Administration

    Cremaffin Plus Sugar Free Syrup is typically prescribed in doses ranging from 15 ml to 30 ml (1 to 2 tablespoons) once or twice daily for adults, as directed by a healthcare professional. It is important to shake the bottle well before each use and measure the dose accurately using a measuring cup or spoon.

    2. Best Time to Take the Syrup

    For optimal effectiveness, Cremaffin Plus Sugar Free Syrup is commonly taken at bedtime to facilitate bowel movement during the night or early morning. Taking the syrup before sleeping allows the active ingredients time to soften stool and stimulate bowel movements naturally. Some doctors may also recommend a dose in the morning before breakfast, but it is advisable not to take the syrup immediately before going to sleep.

    3. Fluid Intake and Hydration Tips During Use

    Adequate fluid intake is essential while using Cremaffin Plus Sugar Free Syrup to manage dehydration and support the laxative effect. Patients are advised to drink plenty of water around 8 to 10 glasses per day and maintain a fiber-rich diet containing fruits, vegetables, and whole grains. Staying hydrated helps the stool remain soft and aids smooth passage through the intestines.

    4. Precautions for Special Populations

    Cremaffin Plus Sugar Free Syrup should be used with caution during pregnancy and breastfeeding, and only under medical advice due to limited safety data. It is not recommended for children below 18 years without a doctor’s guidance. Elderly patients and individuals with kidney disease or intestinal obstruction should consult a healthcare professional before use, as they may be more sensitive to the medication’s effects.

    5. Contraindications and Who Should Avoid This Syrup

    Patients with known allergies to any of the ingredients (liquid paraffin, milk of magnesia, sodium picosulphate) should avoid this syrup. It is contraindicated in cases of intestinal obstruction, undiagnosed abdominal pain, and severe kidney disease. Prolonged use beyond one week should be avoided to reduce dependency, and medical advice should be sought if constipation persists despite treatment.

    Overdose

    If you or anyone else accidentally takes too much of Cremaffin Plus Sugar Free Syrup, consult your doctor immediately or visit the nearby hospital.

    Side Effects Of CREMAFFIN PLUS SYRUP

    Common Side Effects of Cremaffin Plus Syrup

    • diarrhoea
    • nausea
    • vomiting
    • muscle weakness
    • very dry mouth
    • extreme thirst
    • abdominal cramps
    • dizziness
    • gastrointestinal disturbances

    How to handle side effects of sugar-free laxative syrup

    • Handling side effects of sugar-free laxative syrups like Cremaffin Plus involves a few practical steps to ensure safety and comfort
    • If diarrhea occurs, it is important to maintain good hydration by drinking plenty of fluids such as water, fruit juices, or oral rehydration solutions to reduce dehydration. Avoid anti-diarrheal medications unless prescribed by a doctor, as they may worsen the condition
    • For nausea and vomiting, taking the syrup with or just after meals, consuming light and simple foods, and avoiding rich, oily, or spicy meals can help reduce discomfort
    • If side effects persist beyond a few days, worsen, or include symptoms such as rectal bleeding, severe abdominal pain, or dizziness, it is crucial to consult a healthcare provider promptly
    • Avoid exceeding the recommended dosage or prolonged use beyond one week without medical supervision to reduce risk of side effects and dependency

    Signs of dehydration from constipation syrup use

    • Increased thirst and dry mouth
    • Dark yellow or reduced urine output
    • Fatigue or extreme tiredness
    • Dizziness or lightheadedness, especially when standing
    • Dry or flushed skin
    • Headache
    • Muscle cramps or weakness

    Warning & Precautions

    Pregnancy

    Use with Caution

    Cremaffin Plus Sugar Free Syrup should be used with caution in pregnant women because there are no sufficient and well-controlled studies.

    Breastfeeding

    Use with Caution

    Cremaffin Plus Sugar Free Syrup should be used with caution in breast-feeding women because there are no sufficient and well-controlled studies.

    Kidney

    Contraindicated

    Cremaffin Plus Sugar Free Syrup is not recommended for use in patients with kidney disease.  

    Allergy

    Contraindicated

    Do not take Cremaffin Plus Sugar Free Syrup if you are allergic to Liquid Paraffin, Milk of Magnesia, Sodium Picosulphate or any other ingredients of this medicine.

    Use In Pediatrics

    Contraindicated

    Cremaffin Plus Sugar Free Syrup is not recommended for use in children.

    Use In Geriatrics

    Consult your doctor

    For elderly patients, your doctor will decide the right dose depends on your age, body weight and disease condition.

    Who should not take CREMAFFIN PLUS SYRUP

    Cremaffin Plus Sugar Free Syrup is not recommended for use if you have:

    • intestinal obstruction
    • undiagnosed abdominal pain

    Diet and Lifestyle Advice

    Managing Digestive Health During Increased Remote Work and Sedentary Lifestyles

    1. Prioritize Physical Activity

    • Incorporate short regular breaks for movement such as stretching, walking, or simple exercises every hour. Physical activity stimulates intestinal motility, helping to manage constipation linked to prolonged sitting.

    2. Maintain Hydration

    • Drink ample water throughout the day. Staying hydrated softens stool and aids smooth bowel movements. Avoid excessive caffeine and sugary drinks that may dehydrate.

    3. Take Fiber-Rich Diet

    • Include fruits, vegetables, whole grains, and legumes in meals to provide dietary fiber that supports bowel regularity. Aim for gradual increases to avoid gas or bloating.

    4. Establish Consistent Meal and Toilet Times

    • Eat meals at regular intervals to condition digestive rhythms. Respond promptly to natural urges to defecate, avoiding habitually delaying bowel movements.

    5. Manage Stress and Ensure Adequate Sleep

    • Stress and poor sleep can adversely affect digestion. Practice relaxation techniques and maintain a healthy sleep pattern.

    6. Use Gentle Support When Needed

    • For occasional digestive sluggishness, sugar-free laxative syrups like Cremaffin Plus can gently aid stool softening and bowel movement without harsh side effects when used as directed.

    Explain how Cremaffin Plus Sugar Free Syrup can support comfortable digestive rhythm naturally without interfering with daily work schedules

    • Gentle Stool Softening and Lubrication: Liquid paraffin softens and lubricates the stool and intestinal lining, easing passage without causing harsh stimulation or urgency, which helps maintain comfort during work hours.
    • Osmotic Water Retention: Milk of magnesia draws water into the intestines, increasing stool moisture and volume gradually to promote natural bowel movements without sudden disruptions.
    • Stimulated Intestinal Motility: Sodium picosulphate activates the colon's muscles to gently increase intestinal contractions, creating a timely but not abrupt urge to pass stools, aligning with regular daily routines.
    • Nighttime or Fixed Timing Usage: When taken at bedtime or a fixed time as advised, the syrup supports digestive rhythm such that the bowel movement occurs typically overnight or early morning, minimizing interference with daytime activities.
    • Minimized Side Effects for Convenience: Its balanced formulation reduces the likelihood of harsh cramping or diarrhea, supporting a smoother, less disruptive digestive process compatible with sedentary or work-from-home schedules.

    Interactions

    Possible interactions with other medications or herbal supplements

    Medication/Herbal Supplement

    Interaction Description

    Notes and Precautions

    Antihypertensives (e.g., captopril, enalapril)

    May alter the effect of these medications.

    Inform your doctor; monitoring may be needed.

    Antivirals (e.g., atazanavir, fosamprenavir)

    May reduce effectiveness of Cremaffin Plus or vice versa.

    Consult with healthcare provider for adjustments.

    Antihistamines (e.g., fexofenadine)

    Possible altered drug action when taken concurrently.

    Use under medical supervision.

    Antiepileptics (e.g., gabapentin, phenytoin)

    Interaction may affect drug levels or efficacy.

    Close monitoring is advisable.

    Ulcer healing agents (e.g., lansoprazole)

    Possible interaction affecting drug absorption or efficacy.

    Talk to your physician

    Iron preparations

    May have decreased absorption due to gut motility changes.

    Separate timing of dosing recommended.

    Lipid-lowering agents (e.g., rosuvastatin)

    Potential interaction affecting drug metabolism.

    Monitor cholesterol levels as advised.

    Antipsychotics (e.g., sulpiride, phenothiazines)

    Interaction may enhance side effects or alter drug effectiveness.

    Report side effects promptly.

    Corticosteroids (e.g., prednisone)

    Concurrent use may cause electrolyte imbalance.

    Medical supervision required; monitor electrolytes.

    Antibacterials & Antifungals (e.g., azithromycin, rifampicin, itraconazole)

    May decrease laxative effect or vice versa.

    Inform your doctor about all medications.

    Synopsis

    Drug :   Liquid Paraffin, Milk of Magnesia, Sodium Picosulphate
    Pharmacological Category :   Laxatives, Antacids
    Therapeutic Indication :   Constipation, Acidity
    Dosage Forms :   Syrup, Suspension, Liquid, Emulsion

    More Information

    Emphasize the sugar-free nature as a patient-friendly choice supporting dietary restrictions

    • Sugar-free nature of Cremaffin Plus Sugar Free Syrup makes it a patient-friendly option for individuals who need to monitor or limit sugar intake, such as those with diabetes, prediabetes, obesity, or calorie-restricted diets
    • By avoiding added sucrose, the formulation supports digestive comfort without causing unnecessary spikes in blood glucose or adding extra calories, which is especially relevant for long-term cardiovascular and metabolic health.
    • A sugar-free laxative syrup also benefits patients who experience dental sensitivity to sugary liquids or who are advised to reduce simple sugars due to gastrointestinal conditions like irritable bowel tendencies. This makes Cremaffin Plus Sugar Free Syrup a suitable choice for modern lifestyle and clinical dietary restrictions, offering gentle bowel support while aligning with broader nutrition and wellness goals

    FAQs About CREMAFFIN PLUS SYRUP

    Q: What is Cremaffin Plus Sugar Free Syrup used for?

    A: Cremaffin Plus Sugar Free Syrup is indicated for the management of constipation associated with piles, anal fissure, cardiovascular disorder, hernia, pre- and post-operative conditions, endoscopy, and bowel clearance before radioscopy. It also relieves sour stomachs and heartburn.

    Q: What is the best time to take Cremaffin Plus Sugar Free Syrup?

    A: Cremaffin Plus Sugar Free Syrup should be preferably taken during bedtime or as directed by the doctor. Consult your doctor for advice.

    Q: Is Cremaffin Plus Sugar Free Syrup good for acidity?

    A: Yes, Cremaffin Plus Sugar Free Syrup is used for managing symptoms of acidity such as a sour stomach and heartburn.

    Q: Can Cremaffin Plus Sugar Free Syrup cause diarrhea?

    A: Cremaffin Plus Sugar Free Syrup may cause diarrhea. Drink a lot of fluids, such as water, squash, or fruit juice, to keep yourself hydrated. Do not consume any medicine by yourself without consulting your doctor. Ask for your doctor’s advice if diarrhea does not improve.

    Q: Is Cremaffin Plus Sugar Free Syrup safe to use in pregnant and breast-feeding women?

    A: Cremaffin Plus Sugar Free Syrup should be used with caution in pregnant and breast-feeding women because there are no sufficient and well-controlled studies.

    Q: Who should not take Cremaffin Plus Sugar Free Syrup?

    A: Patients with kidney diseases, intestinal obstructions, and undiagnosed abdominal pain or who are allergic to liquid paraffin, milk of magnesia, or sodium picosulfate should not take this medicine. 

    Q: How does Cremaffin Plus Sugar Free Syrup work?

    A: Cremaffin Plus Sugar Free Syrup helps to manage constipation and relieve acidity, where liquid paraffin softens the stools and aids the smooth evacuation out of the bowel. It also eases the pain that is associated with the evacuation of stools. Milk of Magnesia causes the stomach acid to neutralize and acts as a laxative by drawing in more water into the intestines, which softens the stools and increases their volume as well. Sodium picosulfate is activated by the bacteria present in the digestive tract. It increases the accumulation of water in the intestine and also increases the movements of the intestine. This increased movement leads to a feeling of fullness and creates an urge to pass stools.

    Q: What are the common side effects of taking Cremaffin Plus Sugar Free Syrup?

    A: The common side effects of taking Cremaffin Plus Sugar Free Syrup are diarrhea, nausea, vomiting, muscle weakness, dry mouth, extreme thirst, rectal bleeding, abdominal cramps, dizziness, and gastrointestinal disturbances. Consult your doctor if any of the above side effects worsen or persist for a longer duration.

    Q: Can I use Cremaffin Plus Sugar Free Syrup with children?

    A: Cremaffin Plus Sugar Free Syrup is not recommended for use with children. 

    Q: Can I take other medicines while taking Cremaffin Plus Sugar Free Syrup?

    A: Before taking Cremaffin Plus Sugar Free Syrup, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription, or any herbal medicine.

    Q: Is Cremaffin Plus Sugar Free Syrup a habit-forming drug?

    A: No, Cremaffin Plus Sugar Free Syrup is not a habit-forming drug. Consult your doctor for advice.

    Q: Can Cremaffin Plus Sugar Free Syrup be used long term?

    A: Cremaffin Plus Sugar Free Syrup is recommended for short-term use only, usually not exceeding one week, as prolonged use can lead to dependency where bowel movements become reliant on the medication.

    Q: Is Cremaffin Plus Sugar Free Syrup safe for diabetic patients?

    A:  Yes, Cremaffin Plus Sugar Free Syrup is considered a patient-friendly choice for diabetic patients due to its sugar-free formulation, which does not cause blood sugar spikes or add unnecessary calories.

    References

    1. K.D. Tripathi. Drugs for Constipation and Diarrhoea. Essentials of medical pharmacology. Seventh edition. 2013. Page – 673, 674 7 675.

    2. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Milk of Magnesia. [Accessed on 18th November 2025]

    3. Science Direct. KeithHillier. Liquid Paraffin. [Accessed on 18th November 2025]

    5. Leeford Healthcare. Freelex Plus. [Accessed on 18th November 2025]

    6. Drugbank. com. [Accessed on 18th November 2025]

    Useful Diagnostic Tests

    • Ultrasound
    • Colonoscopy

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS
    Last updated on 29 Mar 2024 | 05:31 PM(IST)
    Lab updated