Cosklot Injection 2ml

Introduction About COSKLOT INJECTION

COSKLOT INJECTION contains Ethamsylate, which belongs to the group of medicines called Antihemorrhagic drugs. It is used to manage bleeding from the blood vessels and to manage bleeding before or after an operation.

Ethamsylate exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. Before the management, your doctor might want to do certain blood tests to understand your existing condition.

COSKLOT INJECTION is not recommended for use if you have porphyria (defect in the synthesis of haemoglobin) or bronchial asthma. Before receiving COSKLOT INJECTION inform your doctor if you have hypotension or unstable blood pressure. COSKLOT INJECTION should be used with caution in pregnant women. It is not recommended for use in breastfeeding women. Consult your doctor if you experience any unusual effects while receiving COSKLOT INJECTION.

Uses Of COSKLOT INJECTION

• Prevents and manages bleeding from the blood vessels
• Prevent bleeding before or after an operation

How COSKLOT INJECTION Works

COSKLOT INJECTION exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. It inhibits PGI-2 synthesis and corrects abnormal platelet function.

How to use COSKLOT INJECTION

COSKLOT INJECTION will be given to you only by a doctor or a nurse into the muscles (intramuscularly) or the veins (intravenously). Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.

Warning & Precautions

Pregnancy

COSKLOT INJECTION should be used with caution in pregnant women or if you are planning to have a baby. Consult your doctor before receiving it.

Breastfeeding

COSKLOT INJECTION is not recommended for use in breastfeeding women as it is unknown if the medicine is excreted in breast milk. Consult your doctor before receiving it.

Allergy

Do not receive COSKLOT INJECTION if you are allergic to Ethamsylate or any other ingredients of this medicine.

Lungs

COSKLOT INJECTION is not recommended for use in patients with bronchial asthma. Consult your doctor before receiving COSKLOT INJECTION.

Heart Disease

COSKLOT INJECTION should be used with caution in patients with hypotension and unstable blood pressure. Consult your doctor before receiving COSKLOT INJECTION.

Interactions

A. Drug-Drug interactions:

Before receiving COSKLOT INJECTION, inform your doctor if you are taking any prescription, nonprescription or herbal medicines.

Overdosage:

COSKLOT INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

More Information

• Keep COSKLOT INJECTION out of reach from children
• Store below 30°C

FAQs About COSKLOT INJECTION

What is COSKLOT INJECTION used for?

COSKLOT INJECTION contains Ethamsylate which belongs to the group of medicines called Antihemorrhagic drugs. It is used to manage bleeding from the blood vessels and to manage bleeding before or after an operation.

Can COSKLOT INJECTION be received by pregnant or breastfeeding women?

COSKLOT INJECTION is not recommended for use in breastfeeding women. And it should be used with caution in pregnant women or women planning to have a baby. Consult your doctor before receiving COSKLOT INJECTION.

How COSKLOT INJECTION works?

It exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. It inhibits PGI-2 synthesis and corrects abnormal platelet function.

When is COSKLOT INJECTION contraindicated?

COSKLOT INJECTION is not recommended for use in patients with hypersensitivity to this medicine, porphyria (defect in the synthesis of haemoglobin) and bronchial asthma. Consult your doctor for more information.

Can COSKLOT INJECTION be used in patients with heart problems?

COSKLOT INJECTION should be used with caution in patients with hypotension and unstable blood pressure. Consult your doctor for more information on duration and dosage before receiving COSKLOT INJECTION.

References

1. KD Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of medical pharmacology. Eighth Edition. 2019. Page –662.

2. Ricardo P Garay, Carlo Chiavaroli, Patrick Hannaert. Article name. Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent. National library of medicine, National center for biotechnology information. Pubmed.gov 2006 [Accessed on 9th July 2022] https://pubmed.ncbi.nlm.nih.gov/16772766/

3. M.E.IMorgan I.W.TBenson JBenson R.W.I Cooke. Ethamsylate reduces the incidence of periventricular haemorrhage in very low birthweight babies. The lancet 1981. [Accessed on 9th July 2022] https://www.sciencedirect.com/science/article/abs/pii/S014067368191103X

4. Ethamsylate. CIMS. [Accessed on 9th July 2022] https://www.mims.com/india/drug/info/etamsylate?type=full&mtype=generic

Useful Diagnostic Tests

• Blood tests

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS

Last updated on 09 Nov 2022 | 04:57 PM(IST)