New Revised MRP, 100% GST benefit passed Coriosurge XP 2000IU Injection 1ml
Netmeds First Membership
Quick Links
Introduction About CORIOSURGE XP 2000IU INJECTION
CORIOSURGE XP 2000IU INJECTION contains Chorionic gonadotropin, which belongs to the group of medicines called Gonadotropins. It is used to manage hypogonadism (deficiency of sex hormones) in men. It also helps in the release of matured ovum (eggs) from the ovaries (ovulation) among infertile women after undergoing premanagement with suitable hormonal medicines (such as menotropins or FSH).
It also helps in sustaining pregnancy during the early stages among women who experience habitual abortions. It can also be used in the management of prepubertal cryptorchidism (failure of testis to descend into the scrotum) caused by hormone deficiency in young male children (aged between 4 and 9 years).
During management with CORIOSURGE XP 2000IU INJECTION, your doctor would monitor your health condition through several blood tests and ultrasounds to avoid the risk of side effects like fluid accumulation, abnormally enlarged ovarian follicles, or multiple pregnancies (pregnant with more than one child), especially if you are undergoing assisted reproductive techniques.
Before receiving CORIOSURGE XP 2000IU INJECTION, inform your doctor if you have any forms of cancer in the ovaries, uterus, breasts, or prostate. You must also inform your doctor if you have any damage in the fallopian tubes, as management with CORIOSURGE XP 2000IU INJECTION may cause ectopic pregnancy (pregnancy outside of the womb) in such cases.
CORIOSURGE XP 2000IU INJECTION may cause a false positive pregnancy result in women who take a pregnancy test using their blood or urine. This effect may last up to 10 days even after discontinuing management with CORIOSURGE XP 2000IU INJECTION.
CORIOSURGE XP 2000IU INJECTION may be used to sustain pregnancy during the initial stages (luteal phase). However, it should not be used in the later stages of pregnancy. Therefore, consult your doctor for advice. It is also not recommended for use in breastfeeding women.
The most common side effects of CORIOSURGE XP 2000IU INJECTION are reaching puberty at an early age, pain at the injection site, headaches, and irritability. Consult your doctor if they worsen.
Uses Of CORIOSURGE XP 2000IU INJECTION
- Manage prepubertal cryptorchidism (failure of testis to descend into the scrotum due to sex hormone deficiency) in male children (aged between 4 and 9 years)
- Manage male hypogonadism (failure of testis to produce male sex hormones)
- Induces ovulation among infertile women
- Supports pregnancy among women who experience habitual abortions
How CORIOSURGE XP 2000IU INJECTION Works
CORIOSURGE XP 2000IU INJECTION is a gonadotrophic hormone that stimulates the production of sex hormones in both men and women. In men, it acts by stimulating the release of androgens, which are responsible for the development of secondary sexual characteristics and for regulating the onset of puberty. It also helps to move down the testicles into the scrotum in children having undescended testis.
In women, it triggers the release of mature eggs from the ovaries and helps to sustain pregnancy by supplementing enough female sex hormones (estrogen and progesterone), which are required for maintaining a successful conception.
How to use CORIOSURGE XP 2000IU INJECTION
CORIOSURGE XP 2000IU INJECTION will be given to you only by a doctor or a nurse into the muscle (intramuscularly) or under the skin (subcutaneously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and health condition.
Side Effects Of CORIOSURGE XP 2000IU INJECTION
Common
- headache
- irritability, restlessness, depression
- tiredness
- fluid accumulation (edema)
- precocious puberty (reaching puberty at an early age)
- breast enlargement in men
- pain at the injection site
Rare
Consult your doctor immediately if you experience any of the following side effects after receiving CORIOSURGE XP 2000IU INJECTION:
- signs of ovarian hyperstimulation syndrome (such as lower stomach pain, breast pain, swollen stomach, rapid weight gain, nausea, vomiting, difficulty breathing, clearly enlarged ovaries in ultrasound, fluid accumulation in the lungs, and decreased urine production)
- rupture of ovarian cysts leading to internal bleeding
- multiple pregnancy
- signs of allergic reactions (such as skin rash, redness, itching, rapid or uneven pulse, swelling of the tongue and throat, sneezing, wheezing, or serious difficulty in breathing)
- serious blood clotting problems which may cause chest pain, breathlessness, stroke, or heart attack
- signs of sexual precocity (development of sexual characters) in very young children
Warning & Precautions
Pregnancy
Consult your doctorCORIOSURGE XP 2000IU INJECTION may be used to sustain pregnancy during the initial stages (luteal phase). However, it should not be used in the later stages of pregnancy. Therefore, consult your doctor for advice.
Breastfeeding
ContraindicatedCORIOSURGE XP 2000IU INJECTION is not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by CORIOSURGE XP 2000IU INJECTION.
Alcohol
ContraindicatedAvoid consumption of alcohol while receiving CORIOSURGE XP 2000IU INJECTION.
Kidney
Use with CautionCORIOSURGE XP 2000IU INJECTION should be used with caution in patients having or ever had any kidney diseases. Therefore, consult your doctor before receiving it.
Allergy
ContraindicatedDo not receive CORIOSURGE XP 2000IU INJECTION if you are allergic to chorionic gonadotropin.
Lungs
Use with CautionCORIOSURGE XP 2000IU INJECTION should be used with caution in patients having or ever had asthma. Therefore, consult your doctor before receiving it.
Heart Disease
Use with CautionCORIOSURGE XP 2000IU INJECTION should be used with caution in patients having or ever had heart diseases (such as high blood pressure). Therefore, consult your doctor before receiving it.
Use In Pediatrics
Consult your doctorCORIOSURGE XP 2000IU INJECTION can be used in children aged between 4 and 9 years. It is not recommended for use in children aged under 4 years due to a lack of safety data. However, consult your doctor for advice.
Others
CORIOSURGE XP 2000IU INJECTION is not recommended for use if you:
- have tumors in the pituitary gland (Ex. pituitary adenoma) or uterus (fibroids)
- have ovarian cancer, uterine cancer, breast cancer, or prostate cancer
- have androgen-dependent neoplasms (any forms of tumors caused by excessive androgen production)
- have any type of uncontrolled hormonal disorders (Ex. dysfunction of thyroid gland, pituitary gland, or adrenal glands)
- have failure of ovaries (due to menopause)
- have failure of testis
- are undergoing any surgical procedures in the female reproductive tract (such as tubal occlusion)
- have signs of reaching puberty at a very early age
- have any blood clot problems (like deep vein thrombosis)
- have malformations of sexual organs
- have prepubertal cryptorchidism caused by anatomical obstruction
- have abnormal vaginal bleeding
Before receiving CORIOSURGE XP 2000IU INJECTION, inform your physician if you:
- have or ever had migraine (severe throbbing pain usually on one side of the head)
- have or ever had epilepsy (fits or seizures)
- have damaged fallopian tubes
- are going to have a blood/urine test to detect pregnancy or ovulation
Interactions
A. Drug-Drug interactions:
Before receiving CORIOSURGE XP 2000IU INJECTION, inform your doctor if you are taking:
- other medicines used to manage stimulated ovulation (Ex. menotropin, clomiphene citrate)
Overdosage:
CORIOSURGE XP 2000IU INJECTION will be given to you only by a doctor or nurse, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms like lower stomach pain, swollen stomach, rapid weight gain, nausea, vomiting, breast pain, difficulty breathing, fluid accumulation in the chest, or difficulty passing urine, consult your doctor immediately, as it could be signs of ovarian hyperstimulation syndrome.
Synopsis
| Drug | : | Chorionic Gonadotropin |
| Pharmacological Category | : | Synthetic Hormones |
| Therapeutic Indication | : | Male Hypogonadism, Female Infertility, Prepubertal cryptorchidism |
| Dosage Forms | : | Injection |
More Information
Storage
- Keep CORIOSURGE XP 2000IU INJECTION out of reach of children
- Store CORIOSURGE XP 2000IU INJECTION in a refrigerator (at 2-8°C)
FAQs About CORIOSURGE XP 2000IU INJECTION
Q: Can CORIOSURGE XP 2000IU INJECTION help me lose weight?
A: CORIOSURGE XP 2000IU INJECTION has no effect on fat metabolism, fat distribution, or appetite. There is no substantial evidence to prove that CORIOSURGE XP 2000IU INJECTION can reduce body weight or has its effects on the therapy of obesity. Consult your doctor before receiving CORIOSURGE XP 2000IU INJECTION if you are wishing to use it for losing weight.
Q: Can CORIOSURGE XP 2000IU INJECTION be used in men?
A: Yes. CORIOSURGE XP 2000IU INJECTION can be used to manage hypogonadism and its related complications in men. It helps in the development of secondary sexual characteristics in males who experience delayed onset of puberty and moves down testis into the scrotum among patients having undescended testis. It can also be used in male children aged between 4 and 9 years. Your doctor will prescribe a suitable dose for you depending upon your condition.
Q: Can CORIOSURGE XP 2000IU INJECTION help in getting pregnant?
A: Yes. CORIOSURGE XP 2000IU INJECTION stimulates the release of eggs from the ovaries among infertile women. It also helps to sustain pregnancy among women experiencing habitual abortions by supplementing enough female sex hormones (estrogen and progesterone), which are required for maintaining a successful conception. However, consult your doctor before receiving it.
Q: Can CORIOSURGE XP 2000IU INJECTION cause children to puberty at an early age?
A: Yes. CORIOSURGE XP 2000IU INJECTION can cause prepubertal precocity (reaching puberty in early age) and sexual precocity (development of sexual characters) in very young children due to increased production of sex hormones. Proper dose adjustments and careful monitoring during management with CORIOSURGE XP 2000IU INJECTION can overcome this. However, if your child shows any such changes, consult your doctor immediately. Your doctor might reduce the dose or suggest an alternative therapy.
Q: Can pregnant women use CORIOSURGE XP 2000IU INJECTION?
A: Although, CORIOSURGE XP 2000IU INJECTION helps to sustain pregnancy at the early stages (preferably from luteal phase to first 2 months), it is not recommended for use during the later stages. However, consult your doctor for advice.
Q: Can CORIOSURGE XP 2000IU INJECTION be used to improve sexual performance?
A: No. CORIOSURGE XP 2000IU INJECTION generally does not improve sexual performance. It only stimulates the release of sex hormones in men and women, which ultimately resolves infertility issues and supports better health.
Q: Can CORIOSURGE XP 2000IU INJECTION be self-administered?
A: No. CORIOSURGE XP 2000IU INJECTION is generally administered by a doctor or nurse into the muscle (intramuscularly) or under the skin (subcutaneously). Do not self-administer CORIOSURGE XP 2000IU INJECTION without consulting your doctor. In the case of subcutaneous administration, your doctor may teach you how, when, and where GBNKEYWORD] should be administered. Kindly follow the instructions advised by the doctor if requested for self-administration. Consult your doctor if you have any doubts regarding the administration of CORIOSURGE XP 2000IU INJECTION.
Q: Can CORIOSURGE XP 2000IU INJECTION be used to manage PCOD?
A: Before receiving CORIOSURGE XP 2000IU INJECTION, inform your doctor if you have polycystic ovarian disease (PCOD). Your doctor will decide whether you can use CORIOSURGE XP 2000IU INJECTION or not based on your disease condition.
Q: Can management with CORIOSURGE XP 2000IU INJECTION cause twin pregnancy?
A: Yes. Usage of CORIOSURGE XP 2000IU INJECTION has a higher risk of being pregnant with more than one child at the same time (twin pregnancy or multiple pregnancy) than if conceived naturally. This risk further increases if management with CORIOSURGE XP 2000IU INJECTION is combined with assisted reproductive techniques. To avoid this, your doctor will carefully monitor you through several blood tests (for estradiol levels) and ultrasounds.
Q: Will the use of CORIOSURGE XP 2000IU INJECTION cause breast pain or tenderness?
A: CORIOSURGE XP 2000IU INJECTION may cause breast pain or tenderness in some individuals. It is caused by overstimulation of the ovaries. If the symptom worsens, consult your doctor immediately.
Q: Why am I experiencing positive results in the pregnancy kit after taking CORIOSURGE XP 2000IU INJECTION even though I’m not pregnant?
A: It is because CORIOSURGE XP 2000IU INJECTION contains a medicine that is similar to the endogenous HCG secreted by the placenta of pregnant women. Because pregnancy kits are designed in such a way to capture the levels of naturally produced HCG hormone from the urine of pregnant women, they tend to show a false positive result after receiving CORIOSURGE XP 2000IU INJECTION, even if you are not pregnant.
Q: What precautions need to be followed while taking CORIOSURGE XP 2000IU INJECTION?
A: Before receiving CORIOSURGE XP 2000IU INJECTION, inform your doctor if you have any other problems in reproductive organs like a tumor or cancer, unexplained vaginal bleeding, PCOD, or damage in fallopian tubes. Regularly monitor your health condition through blood tests and ultrasounds as instructed by your doctor. Regularly receive CORIOSURGE XP 2000IU INJECTION as instructed by your physician. If you become pregnant while undergoing management with CORIOSURGE XP 2000IU INJECTION, inform your doctor immediately.
Q: Can CORIOSURGE XP 2000IU INJECTION be used to induce periods?
A: CORIOSURGE XP 2000IU INJECTION is a hormone that is primarily used to improve the chances of getting pregnant in infertile women. Only failure in fertilization or overstimulation of ovaries during therapy can cause miscarriage or menstruation. CORIOSURGE XP 2000IU INJECTION is not a first-line medicine to induce periods among patients who have amenorrhea (lack of periods). Consult your doctor for some alternative therapy.
References
1. KD. Tripathi. Anterior Pituitary Hormones. Hormones and Related Drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page - 241
2. Keith L. Parker and Bernard P. Schimmer. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis. Goodman & Gilman’s: The Pharmacological Basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1123-1124
2. Rina Balducci, V. Toscano, Daniela Casilli, Marella Maroder, F. Sciarra, B. Boscherini. Testicular Responsiveness Following Chronic Administration of hCG (1500 IU Every Six Days) in Untreated Hypogonadotropic Hypogonadism. Thieme. Hormone and Metabolic Research. 1987. [Accessed on 29th August 2024] https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2007-1011782
4. Swashti Agarwal, Doung D. Tu, and Paul F. Austin. Testosterone versus hCG in Hypogonadotropic Hypogonadism – Comparing Clinical Effects and Evaluating Current Practice. Global Pediatric Health. SAGE journals. September 2020. [Accessed on 29th August 2024] https://journals.sagepub.com/doi/full/10.1177/2333794X20958980
5. Piotr Kucharski and Jerzy Niedzielski. Neoadjuvant human Chorionic Gonadotropin (hCG) therapy may improve the position of undescended testis: a preliminary report. NIH. National Library of Medicine, National Center for Biotechnology Information. PubMed Central. August 2013. [Accessed on 29th August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936151/
6. Ilkka Y Järvelä, Juha S Tapanainen, and Hannu Martikainen. Improved pregnancy rate with administration of hCG after intrauterine insemination: a pilot study. NIH. National Library of Medicine, National Center for Biotechnology Information. PubMed Central. February 2010. [Accessed on 29th August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838901/
7. Fresenius Kabi Canada Ltd. Chorionic Gonadotropin for Injection, USP. September 2016. [Accessed on 29th August 2024] https://www.ferring.ca/media/1020/hcg-pi-eng-v21c.pdf
8. Ferring Pharmaceuticals Inc. NOVAREL- gonadotrophin, chorionic. Dailymed. [Revised in May 2018]. [Accessed on 29th August 2024] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=ac6918ff-9dc3-40d9-8619-54b26e4bdfc8&type=display
9. Sanzyme Ltd. Pubergen. 2018. [Accessed on 29th August 2024]. https://www.sanzyme.com/hcg/
10. Bharat Serums and Vaccines Ltd. HUCOG. Highly Purified Chorionic Gonadotrophin Injection. [Accessed on 29th August 2024] https://www.bharatserums.com/assets/pdf/products/Hucog-HP.pdf
11. Cipla Ltd. IVF-C Injection (Human Chorionic Gonadotropin (hCG). Ciplamed.com. [Accessed on 29th August 2024] https://www.ciplamed.com/product-index/ivf-c-injection
12. Bharat Serums and Vaccines Ltd. Ovipure HP. Highly Purified Chorionic Gonadotrophin Injection. [Accessed on 29th August 2024] https://www.bharatserums.com/assets/pdf/products/Ovipure-HP.pdf
13. NV Organon. Health Products Regulatory Authority (HPRA). [Revised in April 2018] [Accessed on 29th August 2024] https://www.hpra.ie/img/uploaded/swedocuments/LicenseSPC_PA0964-005-002_13062018152057.pdf
Useful Diagnostic Tests
- Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance – ELISA
- Follicle Stimulating Hormone (Fsh)
- Complete Blood Count (CBC)/ Hemogram
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Thyroid Stimulating Hormone
- Testosterone
- Testosterone Free
Author Details
