CONCOR AM 2.5mg Tablet is used in the treatment of mild to moderate hypertension (high blood pressure)

CONCOR AM 2.5mg Tablet may also be prescribed for other conditions as determined by your doctor.

• Amlodipine Besylate belongs to a group of medicines known as calcium channel blockers. Amlodipine Besylate prevents the calcium from moving into the blood vessel wall thereby preventing tightening of blood vessel walls. This reduces the blood pressure and improves symptoms of chest pain.

• Bisoprolol belongs to a group of medicines known as beta-blockers. It is a 3^rdgeneration cardio selective beta blocker. Bisoprolol relaxes the blood vessel walls and slows the heart rate. This improves the blood flow, thereby thus reducing the blood pressure.

• The dosage of oral tablets of CONCOR AM 2.5mg Tablet depends on the age, weight and medical condition of an individual. Take CONCOR AM 2.5mg Tablet as prescribed by your doctor.
• You must swallow the tablet with water. Do not chew the tablet.
• CONCOR AM 2.5mg Tablet can be taken before, during or after a meal.
• Take your daily dose at the same time.
• Do not discontinue the medication without consulting a doctor.
• Amlodipine + Bisoprolol is not recommended in children and adolescent under 18 years of age.
• If you miss a dose of CONCOR AM 2.5mg Tablet, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

If you have taken an overdose of CONCOR AM 2.5mg Tablet, please contact your doctor immediately.

Symptoms of overdose of Amlodipine Besylate may include the following:

• Dizziness
• Rapid heart beat
• Fainting

Symptoms of overdose of Bisoprolol may include the following:

• Nausea and vomiting
• Bluish discolouration of lips and nails (cyanosis)
• Slow heart rate
• Low blood pressure
• Fainting
• Atrioventricular block
• Heart failure, cardiogenic shock, cardiac arrest, bronchospasm
• Impairment of consciousness
• Coma

Drugs that interact with Amlodipine Besylate:

• Cyclosporin, Tacrolimus
• Dantrolene
• Diltiazem, Verapamil
• Ketoconazole, Itraconazole
• Rifampicin, Erythromycin, Clarithromycin
• Ritonavir, Indinavir, Nelfinavir
• Simvastatin
• St John's wort

Drugs that interact with Bisoprolol:

• Albuterol, Terbutaline, Theophylline
• Chloroquine
• Clonidine
• Digoxin
• Diltiazem, Nifedipine
• Fluoxetine, Paroxetine
• Glyburide, Metformin
• Hydrochlorothiazide, Chlorthalidone
• Insulin
• Mono amine oxidase inhibitors
• Propafenone
• Quinidine
• Reserpine
• Terbinafine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

Most common side effects of Amlodipine Besylate are:

• Nausea
• Dizziness
• Headache, fatigue
• Flushing
• Drowsiness

Please stop your Amlodipine Besylate tablets and contact your physician immediately if you have

• severe chest pain, palpitations, fainting;
• problems in vision;
• muscle cramps;
• depression;
• itching and skin rashes.

Most common side effects of Bisoprolol are:

• Dry mouth
• Constipation
• Nausea
• Dizziness
• Insomnia
• Anxiety
• Headache, fatigue
• Flushing
• Drowsiness

Please stop your Bisoprolol tablets and contact your physician immediately if you have

• shortness of breath, wheezing;
• yellowing of skin and eyes (inflammation of liver);
• swelling of the hands, feet, ankles or lower legs (oedema);
• unusual weight gain;
• fainting episodes, irregular heart rhythm.

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

• Seek doctor’s advice before taking any other drug or herbal products while on CONCOR AM 2.5mg Tablet.
• Get up slowly after sitting or lying down as CONCOR AM 2.5mg Tablet may cause dizziness and light-headedness.

You are advised not to take CONCOR AM 2.5mg Tablet if

• it has passed the expiry date of the medicine printed on the pack.
• the foil or packaging is torn or shows signs of tampering or there is discoloration.

Tell your doctor if

• you are allergic to CONCOR AM 2.5mg Tablet or to any ingredients of this medicine.
• you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• you have any pre-existing heart disease.
• you have thyrotoxicosis.
• you have liver or kidney disease.
• you have asthma.
• you have diabetes.
• you have peripheral vascular disease.
• you are planning a surgery or any procedure.
• you are pregnant or trying to conceive or are breastfeeding.

If you have taken an overdose of CONCOR AM 2.5mg Tablet, please contact your doctor immediately.

Symptoms of overdose of Amlodipine Besylate may include the following:

• Dizziness
• Rapid heart beat
• Fainting

Symptoms of overdose of Bisoprolol may include the following:

• Nausea and vomiting
• Bluish discolouration of lips and nails (cyanosis)
• Slow heart rate
• Low blood pressure
• Fainting
• Atrioventricular block
• Heart failure, cardiogenic shock, cardiac arrest, bronchospasm
• Impairment of consciousness
• Coma

1. How should CONCOR AM 2.5mg Tablet be stored?

CONCOR AM 2.5mg Tablet does not require any special storage conditions. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

2. Can I drive while taking CONCOR AM 2.5mg Tablet?

CONCOR AM 2.5mg Tablet causes drowsiness, dizziness and headache and affects the driving ability. Avoid driving if you are taking CONCOR AM 2.5mg Tablet.

3. Should I follow any special dietary instructions while taking CONCOR AM 2.5mg Tablet?

Do not take grapefruit or grapefruit juice while on CONCOR AM 2.5mg Tablet. Apart from this, there are no dietary restrictions if you are taking CONCOR AM 2.5mg Tablet.

4. Is CONCOR AM 2.5mg Tablet addictive?

No, CONCOR AM 2.5mg Tablet is not addictive. However, do not take it without consulting your doctor.