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Introduction About COLIGYL DS DRY SYRUP
COLIGYL DS DRY SYRUP contains colistin, which belongs to the group of medicines called Antibiotics. It is used in infants and in children to manage bacterial infections of the gut (stomach and intestines).
Colistin is a polypeptide antibiotic. It binds to the susceptible bacteria and disrupts the composition (lipids and proteins) of the bacterial cell membrane. As a result, it makes the contents of the bacterial cell leak out, which subsequently leads to bacterial killing. It may also inactivate the toxins produced by the bacteria.
Before starting the therapy with COLIGYL DS DRY SYRUP, inform your doctor if your child has any kidney problems. Your doctor would prescribe a low dose of colistin to your child and constantly monitor their kidney functions to avoid the risk of side effects. You must also inform your doctor if your child has any inherited blood or muscle disorders before starting the therapy with COLIGYL DS DRY SYRUP.
Do not give COLIGYL DS DRY SYRUP to your child if your child is allergic to any of its ingredients. The most common side effects of taking COLIGYL DS DRY SYRUP are stomach upset, nausea, vomiting, or dizziness. Contact your doctor if any of these side effects worsen in your child.
Uses Of COLIGYL DS DRY SYRUP
- Manages bacterial infections of the gut in infants and in children
How COLIGYL DS DRY SYRUP Works
COLIGYL DS DRY SYRUP kills the susceptible bacteria that causes infection. It acts by disrupting the composition (lipids and proteins) of the bacterial cell membrane and enters the bacterial cell. This causes the contents of the bacterial cell to leak out, which subsequently leads to bacterial killing. It may also inactivate the effects of toxins produced by the harmful bacteria.
How to use COLIGYL DS DRY SYRUP
Use COLIGYL DS DRY SYRUP as advised by your physician. Reconstitute the medicine with the sterile water given along with the package or with boiled, cooled water before administration. Close the bottle tightly and shake the mixture vigorously for at least 10-15 minutes until it forms a uniform mixture. Measure the medicine using the measuring cup given along with the package and administer it to your child.
Your doctor will decide the correct dose, quantity (ml), and duration of therapy for your child depending upon their age, body weight, and severity of infection. Shake the medicine well before each use. Do not stop giving COLIGYL DS DRY SYRUP to your child without consulting your doctor, even if they feel better after a few days of therapy. Continue to give COLIGYL DS DRY SYRUP for the stipulated duration mentioned by your doctor to achieve maximum benefits.
Side Effects Of COLIGYL DS DRY SYRUP
Common
- nausea, vomiting
- loss of appetite
- dizziness
- stomach upset
- skin rash
How To Manage Side Effects

Dizziness Or Drowsiness
Make your child rest and relax. Restrict them from playing outdoors. Avoid indulging them in activities that require proper concentration, such as riding a bicycle. Consult your doctor if dizziness worsens in your child.

Nausea And Vomiting
Give COLIGYL DS DRY SYRUP to your child along with meals or after a snack. Provide them only with simple meals. Restrict your children from oil-rich or spicy food. Contact your doctor if nausea worsens in your child.
Warning & Precautions

Driving and Using Machines
ContraindicatedCOLIGYL DS DRY SYRUP may cause dizziness. Therefore, restrict your child from playing outdoors. Avoid indulging them in activities that require proper concentration, such as riding a bicycle.

Kidney
Use with CautionCOLIGYL DS DRY SYRUP should be used with caution in children with kidney problems. Therefore, inform your doctor before administering it to your child.

Allergy
ContraindicatedInform your doctor before starting the therapy with COLIGYL DS DRY SYRUP if your child is allergic to colistin or other polymyxin antibiotics.

Use In Pediatrics
Consult your doctorCOLIGYL DS DRY SYRUP can be used in infants and in children. However, it should be used only if prescribed by the physician. Therefore, consult your doctor before giving it to your child.
Interactions
A. Drug-Drug Interaction:
Before giving COLIGYL DS DRY SYRUP to your child, inform your doctor if your child is taking any of the following medicines such as:
- other antibiotics such as aminoglycosides (Ex. netilmicin, gentamicin, amikacin, and tobramycin), cephalosporins (Ex. cefixime, ceftriaxone), macrolides (Ex. azithromycin, clarithromycin, or erythromycin), or fluoroquinolones (ofloxacin, norfloxacin, and ciprofloxacin)
Overdosage:
If your child or anyone else accidentally took more COLIGYL DS DRY SYRUP, consult your doctor immediately.
Synopsis
Drug | : | Colistin |
Pharmacological Category | : | Polypeptide antibiotics |
Therapeutic Indication | : | Bacterial infection |
Dosage Forms | : |
Injection, Syrup, Suspension, Dry syrup, Tablet |
More Information
Storage
- Keep COLIGYL DS DRY SYRUP out of reach of children
- Store COLIGYL DS DRY SYRUP room temperature
- Use the reconstituted medicine within 7 days of mixing
FAQs About COLIGYL DS DRY SYRUP
Q: What is the use of COLIGYL DS DRY SYRUP?
A: COLIGYL DS DRY SYRUP is an antibiotic used to manage bacterial infections of the gut in infants and in children. It acts by killing the susceptible bacteria that causes infection.
Q: What COLIGYL DS DRY SYRUP does to my child?
A: COLIGYL DS DRY SYRUP kills the susceptible bacteria in your child that causes infection. It acts by disrupting the composition (lipids and proteins) of the bacterial cell membrane and enters the bacterial cell. This causes the contents of the bacterial cell to leak out, which subsequently leads to bacterial killing. It may also inactivate the effects of toxins produced by the harmful bacteria.
Q: What are the side effects of COLIGYL DS DRY SYRUP?
A: The most common side effects of receiving COLIGYL DS DRY SYRUP are stomach upset, nausea, vomiting, or dizziness. Contact your doctor if any of these side effects worsen in your child.
Q: How to use COLIGYL DS DRY SYRUP?
A: Use COLIGYL DS DRY SYRUP as advised by your physician. Reconstitute the medicine with the sterile water given along with the package or with boiled, cooled water before administration. Close the bottle tightly and shake the mixture vigorously for at least 10-15 minutes until it forms a uniform mixture. Measure the medicine using the measuring cup given along with the package and administer it to your child. Shake the medicine well before each use.
Q: Can COLIGYL DS DRY SYRUP be used in children?
A: Yes. COLIGYL DS DRY SYRUP can be used in infants and in children if prescribed by the physician. Therefore, consult your doctor before using.
Q: What precautions do I need to follow while taking COLIGYL DS DRY SYRUP?
A: Before starting the therapy with COLIGYL DS DRY SYRUP, inform your doctor if your child has any kidney problems. Your doctor would prescribe a low dose of colistin to your child and constantly monitor their kidney functions to avoid the risk of side effects. You must also inform your doctor if your child has any inherited blood or muscle disorders before starting the therapy with COLIGYL DS DRY SYRUP. Do not give COLIGYL DS DRY SYRUP to your child if your child is allergic to any of its ingredients.
Q: What medicines should I avoid while taking COLIGYL DS DRY SYRUP?
A: Avoid giving other antibiotics to your child along with COLIGYL DS DRY SYRUP without consulting your doctor. Concomitant use of antibiotics along with COLIGYL DS DRY SYRUP may potentiate the effects of COLIGYL DS DRY SYRUP and may lead to unwanted side effects.
Q: Is COLIGYL DS DRY SYRUP safe?
A: COLIGYL DS DRY SYRUP is generally safe when used in the doses recommended by your doctor. Therefore, carefully follow your doctor's instructions and inform your doctor immediately if your child experiences any unpleasant side effects after taking COLIGYL DS DRY SYRUP.
Q: Can I take COLIGYL DS DRY SYRUP during pregnancy?
A: COLIGYL DS DRY SYRUP is intended for use only in infants and in children. It is not suitable for use in pregnant women. Therefore, consult your doctor before taking it.
Q: Can I stop giving COLIGYL DS DRY SYRUP to my child without consulting the doctor?
A: Do not stop giving COLIGYL DS DRY SYRUP to your child without consulting your doctor, even if they feel better after a few days of therapy. Continue to give COLIGYL DS DRY SYRUP for the stipulated duration mentioned by your doctor to achieve maximum benefits.
Q: What should I do if I forget to take a dose of COLIGYL DS DRY SYRUP?
A: If a dose of COLIGYL DS DRY SYRUP is missed, take it as soon as you remember. However, if it is time for the next dose of COLIGYL DS DRY SYRUP, skip the missed dose and give the next one regularly to your child. Do not give a double dose of COLIGYL DS DRY SYRUP to compensate for the missed ones.
References
1. K.D. Tripathi. Macrolide and other antibacterial antibiotics. Essentials of Medical Pharmacology. Seventh Edition. Page – 759.
2. Ferdinando F. Andrade, Daniela Silva, Acacio Rodrigues, and Cidalia Pina-Vaz. National Library of Medicine. Colistin Update on Its Mechanism of Action and Resistance, Present and Future Challenges. NIH. National Library of Medicine. National Centre of Biotechnology Information. PMC PubMed Central. November 2020. [Accessed on 21st August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692639/
3. MK Medicine. [Accessed on 21st August 2024] https://www.mkmedicine.in/colistin-sulphate-12.5-mg-dry-syrup.html
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