COELONE contains Methylprednisolone which belongs to the group of medicines called corticosteroids. It is used to treat various inflammatory and allergic conditions affecting the adrenal glands (e.g. adrenocortical insufficiency), bones and joints (e.g. arthritis), collagen (e.g. systemic lupus erythematosus), skin (e.g. psoriasis and dermatitis), lungs (e.g. asthma, pulmonary tuberculosis), eyes (e.g. uveitis, keratitis, neuritis, iritis), blood and lymph (e.g. anemia, leukemias and lymphomas), bowel (e.g. Crohn’s disease and ulcerative colitis), brain (e.g. tuberculous meningitis) and muscle (e.g. dermatomyositis and polymyositis).
Corticosteroids are produced naturally in the body and are necessary for many body functions. Supplying your body with extra corticosteroid such as methylprednisolone can help your body in conditions associated with adrenal insufficiency. COELONE acts by changing the expression of various genes and proinflammatory cytokines that results in inflammation. It also decreases the number of circulating lymphocytes and induces apoptosis in sensitive tumor cells.
Do not eat grapes or drink grapefruit juice while taking this medicine. Do not stop taking this medicine abruptly without consulting your doctor, as it may result in withdrawal symptoms. While taking this medicine, inform your doctor immediately if you experience any signs of mental problems such as depression, anxiety, difficulty in thinking, confusion, memory loss, hallucinations or suicidal thoughts. Your doctor might lower your dose or think of an alternative treatment.
COELONE is contraindicated in patients having any serious fungal infection. Consult your doctor before taking. Before taking this medicine inform your doctor if you have any liver, kidney, heart or stomach problems. If you are pregnant, or think you may be pregnant or breastfeeding, please inform your doctor, because this medicine may affect the growth of the unborn baby and growing infants.