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Introduction About CLOBETA GM CREAM
CLOBETA GM CREAM is a combination of Clobetasol, Miconazole and Neomycin which belongs to the group of medicines called Corticosteroids, Antifungals and Antibiotics. It is used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection.
CLOBETA GM CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox) and perforated eardrum. Contact your doctor before applying. CLOBETA GM CREAM should be used with caution in patients with liver or kidney disease. Contact your doctor before applying.
CLOBETA GM CREAM is generally not recommended for use in pregnancy unless considered clearly necessary. CLOBETA GM CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying. CLOBETA GM CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.
Dosage adjustment is not required for CLOBETA GM CREAM in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying. The most common side effects of this medicine are skin rash, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.
Uses Of CLOBETA GM CREAM
- Used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection
How CLOBETA GM CREAM Works
CLOBETA GM CREAM helps to manage infection, where Clobetasol have anti-inflammatory, antipruritic, and vasoconstrictive properties, which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Miconazole belongs to antifungal which stops the growth of fungi while Neomycin belongs to antibiotic which stops the growth of bacteria in the skin.
How to use CLOBETA GM CREAM
Apply CLOBETA GM CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes, face, groin or in the skin folds.
Side Effects Of CLOBETA GM CREAM
Common
- skin rash, itching, redness
- burning sensation
- contact dermatitis
Rare
Stop applying CLOBETA GM CREAM and contact your physician immediately if you experience any of the following side effects:
- severe allergic reactions such as anaphylaxis or angioedema (skin rash, swelling of the face, lips, tongue, or throat causing breathing difficulty)
How To Manage Side Effects
Skin rash Or Itching
Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if itching worsens.
Warning & Precautions
Pregnancy
Monitoring requiredCLOBETA GM CREAM is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before applying.
Breastfeeding
Use with CautionCLOBETA GM CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.
Kidney
Use with CautionCLOBETA GM CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.
Liver
Use with CautionCLOBETA GM CREAM should be used with caution in patients with liver disease. Contact your doctor before applying.
Allergy
ContraindicatedDo not use CLOBETA GM CREAM if you are allergic to Clobetasol, Miconazole, Neomycin, or to any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedCLOBETA GM CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.
Use In Geriatrics
Use with CautionDosage adjustment is not required for CLOBETA GM CREAM in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying.
Others
CLOBETA GM CREAM is not recommended for use if you have:
- rosacea
- acne vulgaris
- perioral dermatitis
- perianal and genital pruritus
- viral infections (ex. herpes simplex, chickenpox)
- perforated eardrum
Interactions
A. Drug-Drug interactions:
Before applying CLOBETA GM CREAM tell your doctor if you are taking,
- ritonavir (medicines used for HIV infections)
- itraconazole (medicines used for fungal infections)
- amikacin, gentamicin (medicines used for bacterial infections)
- neuromuscular blocking agents like atracurium, pancuronium (medicines used in anaesthesia)
- warfarin (medicines used to manage or manage blood clots)
Overdosage:
If you or anyone else accidentally uses too much of CLOBETA GM CREAM, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Clobetasol, Miconazole, Neomycin |
| Pharmacological Category | : | Corticosteroids, Antifungals, Antibiotics |
| Therapeutic Indication | : | Skin infections |
| Dosage Forms | : | Cream, Lotion, Ointment |
More Information
- Keep out of reach of children
- Store CLOBETA GM CREAM below 25°C
FAQs About CLOBETA GM CREAM
Q: What are the possible side effects of applying CLOBETA GM CREAM?
A: The most common side effects of this medicine are skin rash, urticaria, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.
Q: Can I use CLOBETA GM CREAM in children?
A: CLOBETA GM CREAM is not recommended for use in children under 2 years of age. Contact your doctor before applying.
Q: For what conditions CLOBETA GM CREAM is used?
A: CLOBETA GM CREAM is used to manage resistant dermatoses (skin infections) with secondary bacterial or fungal infection.
Q: Does CLOBETA GM CREAM cause itching on the skin?
A: Yes, CLOBETA GM CREAM may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, consult your doctor for advice.
Q: Can I stop using CLOBETA GM CREAM when my symptoms are relieved?
A: No, do not stop using CLOBETA GM CREAM and complete the full course of management, even if you feel better. Your symptoms may improve before the infection is completely managed.
Q: Who should not use CLOBETA GM CREAM?
A: CLOBETA GM CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), perforated eardrum. Contact your doctor before applying.
References
1. K.D. Tripathi. Drugs acting on the skin and mucous membrane, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 792, 750.
2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051
3. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/4189
4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin
5. Blue Cross labs. Clobetasol, Miconazole and Neomycin. [Revised on May 2020] [Accessed on 24th June 2022] https://www.bluecrosslabs.com/img/sections/SONADERM-NM-CREAM.pdf
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