INTRODUCTION

CILACAR 10 contains a medicine called cilnidipine which belongs to the group of medicines called calcium channel blockers. It is indicated for the management of hypertension. Hypertension (high blood pressure), is a medical condition in which the blood vessels have persistently raised pressure. It can increase the risk of heart, brain, kidney and other diseases.

Cilnidipine lowers your blood pressure by preventing the entry of calcium into the cardiac cells. Generally, calcium ions enter the heart muscle cells during each heartbeat and helps in cardiac contractility. By blocking calcium entry, cilnidipine allows blood vessels to relax and dilate, thereby reducing blood pressure. Along with the therapy, your doctor would also recommend you avoid smoking or alcohol consumption, a well-balanced diet with reduced salt intake, weight management and to have an undisturbed sleep.

The most common side effects of taking this medicine are dizziness, flushing, palpitations and headache. If any of these symptoms bother you, consult your doctor. This medicine is contraindicated in patients with other severe heart diseases like hypotension, heart failure or angina. Consult your doctor before taking. Avoid concomitant use of CILACAR 10 with other antihypertensive drugs without consulting your doctor. Regularly monitor your blood pressure levels as a precaution to avoid unwanted side effects. Before taking this medicine inform your doctor if you are pregnant or breastfeeding.

USES OF CILACAR 10

• Management of Hypertension

HOW CILACAR 10 WORKS

Cilnidipine prevents the entry of calcium ions into the cardiac cells by inhibiting the L-type calcium channels of blood vessels. Blocking calcium influx, suppresses the contraction of blood vessels and dilates them, thereby reducing blood pressure.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF CILACAR 10

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea):

Try taking this medicine with, or just after meal and stick to simple meals. Avoid eating rich or spicy food.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your doctor to recommend a painkiller.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking,

• other medicines used to treat heart problems (such as quinidine, propranolol, digoxin)
• medicines used to treat psychotic disorders (e.g. risperidone, quetiapine, olanzapine)
• aldesleukin (used to treat advanced renal carcinoma)
• phenytoin (used to treat epilepsy)
• rifampicin (used to treat tuberculosis)
• erythromycin (used to treat bacterial infections)

SYNOPSIS

MORE INFORMATION

Store at room temperature and keep out of reach of children.

FAQs ABOUT CILACAR 10

Can CILACAR 10 be used with telmisartan?

Avoid concomitant use of this medicine with other antihypertensive drugs without consulting your doctor.

Can CILACAR 10 be crushed?

No. Swallow the tablet as a whole with a drink of water. Do not crush or chew the medicine.

Can CILACAR 10 be used during pregnancy?

This medicine is contraindicated for use during pregnancy. Do not take this medicine if you are pregnant without consulting your doctor.

REFERENCES

1. Lionel H. Opie. Calcium channel blockers. Drugs for the heart. 8th Edition. 2013. Page- 88-89.

2. Boryung Pharmaceutical Co., Ltd. Cilnidipine Effect on High Blood Pressure and Cerebral Perfusion in Ischemic Stroke Patients With Hypertension. NIH U.S. Nation Library of Medicine ClinicalTrials.gov. [Revised on December 2008] [Accessed on 27th October 2020] https://www.clinicaltrials.gov/ct2/show/NCT00325637

3. K. Sarat Chandra, G. Ramesh. The fourth-generation Calcium channel blocker: Cilnidipine. NCBI; PMC US National Library of Medicine, National Institutes of Health. December 2013. [Accessed 27th October 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905258/

4. Centaur pharma [Accessed 27th October 2020] https://www.centaurpharma.com/downloads/CENTAPRES.pdf

USEFUL DIAGNOSTIC TESTS

Activated Partial Thromboplastin Time

Complete Blood Count

Kidney Function Test

Prothrombin Time