Availability & Expiry
INTRODUCTION
CETIL CV 500MG TABLET is a combination of Cefuroxime and Clavulanic Acid which belongs to the group of medicines called Antibiotics and Beta-lactamase inhibitors respectively. It treats various types of bacterial infections like pharyngitis and/or tonsillitis, acute bacterial otitis media, acute bacterial maxillary sinusitis, lower respiratory tract infections including pneumonia, acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis, skin and skin structure infections, urinary tract infections, bone and joint infections, gonorrhoea (uncomplicated and disseminated gonococcal infections), early Lyme disease (erythema migrans), septicemia, meningitis and in switch therapy (injectable to oral) after surgery when patient’s condition is improved.
Before taking CETIL CV 500MG TABLET, inform your doctor if you have a history of colitis, liver problems or kidney problems. CETIL CV 500MG TABLET should be used with caution in patients who are penicillin sensitive. CETIL CV 500MG TABLET should be used with caution in pregnant women and is not recommended for use in breastfeeding women.
CETIL CV 500MG TABLET is not recommended for use in children under the age of three months. The most common side effects of taking CETIL CV 500MG TABLET are nausea, vomiting, diarrhoea abdominal discomfort or pain. Ask your doctor for advice if any of these side effects worsen or don’t improve.
USES OF CETIL CV 500MG TABLET
CETIL CV 500MG TABLET is used for the treatment of various bacterial infections such as:
- pharyngitis and/or tonsillitis
- acute bacterial otitis media
- acute bacterial maxillary sinusitis
- lower respiratory tract infections including pneumonia
- acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis
- skin and skin structure infections
- urinary tract infections
- bone and joint infections
- gonorrhoea (uncomplicated and disseminated gonococcal infections)
- early Lyme disease (erythema migrans)
- septicemia
- meningitis
- switch therapy (injectable to oral) after surgery when the patient’s condition is improved
HOW CETIL CV 500MG TABLET WORKS
CETIL CV 500MG TABLET is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by preventing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.
DIRECTIONS FOR USE
Take CETIL CV 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will determine the correct dose and duration of CETIL CV 500MG TABLET for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF CETIL CV 500MG TABLET
COMMON
- nausea
- vomiting
- diarrhoea
- abdominal discomfort or pain
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take this medicine with meals or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Consult with your doctor if the symptom doesn’t improve.
Vomiting:
Drink clear or ice-cold drinks; eat light, bland foods; and avoid fried, oily or sweet foods. Consult with your doctor if the symptom doesn’t improve.
Diarrhoea:
Drink a lot of fluids, such as water, squash or fruit juice, to keep yourself hydrated. Do not take any medication without first consulting your doctor. Consult with your doctor if the symptom doesn’t improve.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician.
WARNING & PRECAUTIONS
PREGNANCY
CETIL CV 500MG TABLET should be used with caution in pregnant women only if needed as there are no adequate and well-controlled studies. Consult your doctor before taking it.
BREASTFEEDING
CETIL CV 500MG TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Dizziness has been reported during treatment with CETIL CV 500MG TABLET and may affect the ability to drive and use machines. Consult your physician before taking CETIL CV 500MG TABLET.
KIDNEY
CETIL CV 500MG TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.
LIVER
CETIL CV 500MG TABLET should be taken with caution in patients with liver problems. Consult your doctor for advice.
ALLERGY
Do not take CETIL CV 500MG TABLET if you are allergic to Cefuroxime, Clavulanate any other cephalosporin antibiotic such as cefadroxil or cephalexin, penicillin or any of the other ingredients of this medicine.
OTHERS
Before taking CETIL CV 500MG TABLET inform your doctor if you have:
- sensitivity to penicillin
- colitis
Use in Pediatrics:
CETIL CV 500MG TABLET is not recommended for use in children under 3 months of age as the safety and efficacy of CETIL CV 500MG TABLET have not been established in this group. Consult your physician for advice before taking it.
Use in Geriatrics:
CETIL CV 500MG TABLET should be taken with caution in elderly patients. Consult your doctor for advice.
INTERACTIONS
A. Drug-Drug Interactions:
Inform your physician if you are taking any of the following drugs before taking CETIL CV 500MG TABLET:
- antacids such as sodium bicarbonate and aluminium hydroxide (used to treat stomach problems)
- probenecid (used to treat gout)
- oral contraceptives (combined oral estrogen/progesterone)
- potent diuretics (Ex. chlorothiazide, indapamide)
Overdosage:
If you or anyone else accidentally take too much of CETIL CV 500MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CETIL CV 500MG TABLET may include cerebral irritation leading to convulsions.
SYNOPSIS
| Drug | : | Cefuroxime, Clavulanic Acid |
| Pharmacological Category | : | Antibiotics, Beta-lactamase inhibitors |
| Therapeutic Indication | : | Infections |
| Dosage Forms | : | Tablet, Dry syrup |
MORE INFORMATION
- Keep CETIL CV 500MG TABLET out of reach from children
- Store at a temperature below 25°C in a cool and dry place
FAQs ABOUT CETIL CV 500MG TABLET
Q: What precautions are to be taken if I take too much CETIL CV 500MG TABLET?
A: If you or anyone else accidentally takes too much CETIL CV 500MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CETIL CV 500MG TABLET may include cerebral irritation leading to convulsions.
Q: Is it safe for children to use CETIL CV 500MG TABLET?
A: CETIL CV 500MG TABLET is not recommended for use in children under 3 months of age, as the safety and efficacy of CETIL CV 500MG TABLET have not been established in this group. Consult your physician for advice before taking
Q: Can CETIL CV 500MG TABLET be given to pregnant and breastfeeding women?
A: CETIL CV 500MG TABLET should be used with caution in pregnant women only if needed, as there are no adequate and well-controlled studies. CETIL CV 500MG TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your physician before taking it.
Q: How does CETIL CV 500MG TABLET act?
A: CETIL CV 500MG TABLET is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by preventing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.
Q: What are the common side effects of CETIL CV 500MG TABLET?
A: The most common side effects of taking CETIL CV 500MG TABLET are nausea, vomiting, diarrhoea, abdominal discomfort or pain. Ask your doctor for advice if any of these side effects worsen or don’t improve.
REFERENCES
1. KD Tripathi. Beta-Lactam Antibiotics, Antimicrobial Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 721 & 728.
2. Himanshu Gupta, Reena Gupta, Sumit Rai, Himanshu Kataria. Is empirical use of the antibiotic combination of cefuroxime and clavulanic acid rational? Journal of Global Antimicrobial Resistance. March 2019. [Accessed on 8th July 2022] https://www.researchgate.net/publication/330130875_Is_empirical_use_of_the_antibiotic_combination_of_cefuroxime_and_clavulanic_acid_rational
3. Dr. Anuradha De, Dr. Ruchi Tayal and Dr. Sujata Baveja. Comparison of the sensitivity of Cefuroxime- Clavulanic acid combination vs Cefuroxime alone in biofilm and/or beta-lactamase-producing bacteria. December 2015. [Accessed on 8th July 2022] https://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_3_january_issue_1/1451545156.pdf
4. Umano Healthcare. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://umanohealthcare.com/umoxim-cv/
5. Incepta pharma. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] http://www.inceptapharma.com/product-details.php?pid=510
6. Radiant Pharmaceuticals. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] http://www.radiantpharmabd.com/products/78/details
7. ACI Limited. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://www.aci-bd.com/Brand/Cerox%20CV.pdf
8. MK Medicine. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://www.mkmedicine.in/cefuroxime-axetil-ip-500-mg-clavulanic-acid-125-mg-tablet.html
9. Wellona Pharma. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://wellonapharma.com/product/finished/cefuroxime-and-potassium-clavulanate-tablets
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Chest X-ray
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