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(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Khandelwal Laboratories Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

CEFSAFE CV 500 TABLET is a combination of Cefuroxime and Clavulanic Acid which belongs to the group of medicines called Antibiotics and Beta-lactamase inhibitors respectively. It treats various types of bacterial infections like pharyngitis and/or tonsillitis, acute bacterial otitis media, acute bacterial maxillary sinusitis, lower respiratory tract infections including pneumonia, acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis, skin and skin structure infections, urinary tract infections, bone and joint infections, gonorrhoea (uncomplicated and disseminated gonococcal infections), early Lyme disease (erythema migrans), septicemia, meningitis and in switch therapy (injectable to oral) after surgery when patient’s condition is improved.

Before taking CEFSAFE CV 500 TABLET, inform your doctor if you have a history of colitis, liver problems or kidney problems. CEFSAFE CV 500 TABLET should be used with caution in patients who are penicillin sensitive. CEFSAFE CV 500 TABLET should be used with caution in pregnant women and is not recommended for use in breastfeeding women.

CEFSAFE CV 500 TABLET is not recommended for use in children under the age of three months. The most common side effects of taking CEFSAFE CV 500 TABLET are nausea, vomiting, diarrhoea abdominal discomfort or pain. Ask your doctor for advice if any of these side effects worsen or don’t improve.

USES OF CEFSAFE CV 500 TABLET

CEFSAFE CV 500 TABLET is used for the treatment of various bacterial infections such as:

  • pharyngitis and/or tonsillitis
  • acute bacterial otitis media
  • acute bacterial maxillary sinusitis
  • lower respiratory tract infections including pneumonia
  • acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis
  • skin and skin structure infections
  • urinary tract infections
  • bone and joint infections
  • gonorrhoea (uncomplicated and disseminated gonococcal infections)
  • early Lyme disease (erythema migrans)
  • septicemia
  • meningitis
  • switch therapy (injectable to oral) after surgery when the patient’s condition is improved

HOW CEFSAFE CV 500 TABLET WORKS

CEFSAFE CV 500 TABLET is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by preventing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.

DIRECTIONS FOR USE

Take CEFSAFE CV 500 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will determine the correct dose and duration of CEFSAFE CV 500 TABLET for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF CEFSAFE CV 500 TABLET

COMMON

  • nausea
  • vomiting
  • diarrhoea
  • abdominal discomfort or pain

HOW TO MANAGE SIDE EFFECTS

Nausea:

Take this medicine with meals or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Consult with your doctor if the symptom doesn’t improve.

Vomiting:

Drink clear or ice-cold drinks; eat light, bland foods; and avoid fried, oily or sweet foods. Consult with your doctor if the symptom doesn’t improve.

Diarrhoea:

Drink a lot of fluids, such as water, squash or fruit juice, to keep yourself hydrated. Do not take any medication without first consulting your doctor. Consult with your doctor if the symptom doesn’t improve.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician.

WARNING & PRECAUTIONS

PREGNANCY

CEFSAFE CV 500 TABLET should be used with caution in pregnant women only if needed as there are no adequate and well-controlled studies. Consult your doctor before taking it.

BREASTFEEDING

CEFSAFE CV 500 TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Dizziness has been reported during treatment with CEFSAFE CV 500 TABLET and may affect the ability to drive and use machines. Consult your physician before taking CEFSAFE CV 500 TABLET.

KIDNEY

CEFSAFE CV 500 TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.

LIVER

CEFSAFE CV 500 TABLET should be taken with caution in patients with liver problems. Consult your doctor for advice.

ALLERGY

Do not take CEFSAFE CV 500 TABLET if you are allergic to Cefuroxime, Clavulanate any other cephalosporin antibiotic such as cefadroxil or cephalexin, penicillin or any of the other ingredients of this medicine.

OTHERS

Before taking CEFSAFE CV 500 TABLET inform your doctor if you have:

  • sensitivity to penicillin
  • colitis

Use in Pediatrics:

CEFSAFE CV 500 TABLET is not recommended for use in children under 3 months of age as the safety and efficacy of CEFSAFE CV 500 TABLET have not been established in this group. Consult your physician for advice before taking it.

Use in Geriatrics:

CEFSAFE CV 500 TABLET should be taken with caution in elderly patients. Consult your doctor for advice.

INTERACTIONS

A. Drug-Drug Interactions:

Inform your physician if you are taking any of the following drugs before taking CEFSAFE CV 500 TABLET:

  • antacids such as sodium bicarbonate and aluminium hydroxide (used to treat stomach problems)
  • probenecid (used to treat gout)
  • oral contraceptives (combined oral estrogen/progesterone)
  • potent diuretics (Ex. chlorothiazide, indapamide)

Overdosage:

If you or anyone else accidentally take too much of CEFSAFE CV 500 TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CEFSAFE CV 500 TABLET may include cerebral irritation leading to convulsions.

SYNOPSIS

Drug :   Cefuroxime, Clavulanic Acid
Pharmacological Category :   Antibiotics, Beta-lactamase inhibitors
Therapeutic Indication :   Infections
Dosage Forms :   Tablet, Dry syrup

MORE INFORMATION

  • Keep CEFSAFE CV 500 TABLET out of reach from children
  • Store at a temperature below 25°C in a cool and dry place

FAQs ABOUT CEFSAFE CV 500 TABLET

Q: What precautions are to be taken if I take too much CEFSAFE CV 500 TABLET?

A: If you or anyone else accidentally takes too much CEFSAFE CV 500 TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CEFSAFE CV 500 TABLET may include cerebral irritation leading to convulsions.

Q: Is it safe for children to use CEFSAFE CV 500 TABLET?

A: CEFSAFE CV 500 TABLET is not recommended for use in children under 3 months of age, as the safety and efficacy of CEFSAFE CV 500 TABLET have not been established in this group. Consult your physician for advice before taking

Q: Can CEFSAFE CV 500 TABLET be given to pregnant and breastfeeding women?

A: CEFSAFE CV 500 TABLET should be used with caution in pregnant women only if needed, as there are no adequate and well-controlled studies. CEFSAFE CV 500 TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your physician before taking it.

Q: How does CEFSAFE CV 500 TABLET act?

A: CEFSAFE CV 500 TABLET is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by preventing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.

Q: What are the common side effects of CEFSAFE CV 500 TABLET?

A: The most common side effects of taking CEFSAFE CV 500 TABLET are nausea, vomiting, diarrhoea, abdominal discomfort or pain. Ask your doctor for advice if any of these side effects worsen or don’t improve.

REFERENCES

1. KD Tripathi. Beta-Lactam Antibiotics, Antimicrobial Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 721 & 728.

2. Himanshu Gupta, Reena Gupta, Sumit Rai, Himanshu Kataria. Is empirical use of the antibiotic combination of cefuroxime and clavulanic acid rational? Journal of Global Antimicrobial Resistance. March 2019. [Accessed on 8th July 2022] https://www.researchgate.net/publication/330130875_Is_empirical_use_of_the_antibiotic_combination_of_cefuroxime_and_clavulanic_acid_rational

3. Dr. Anuradha De, Dr. Ruchi Tayal and Dr. Sujata Baveja. Comparison of the sensitivity of Cefuroxime- Clavulanic acid combination vs Cefuroxime alone in biofilm and/or beta-lactamase-producing bacteria. December 2015. [Accessed on 8th July 2022] https://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_3_january_issue_1/1451545156.pdf

4. Umano Healthcare. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://umanohealthcare.com/umoxim-cv/

5. Incepta pharma. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] http://www.inceptapharma.com/product-details.php?pid=510

6. Radiant Pharmaceuticals. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] http://www.radiantpharmabd.com/products/78/details

7. ACI Limited. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://www.aci-bd.com/Brand/Cerox%20CV.pdf

8. MK Medicine. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://www.mkmedicine.in/cefuroxime-axetil-ip-500-mg-clavulanic-acid-125-mg-tablet.html

9. Wellona Pharma. Cefuroxime and Clavulanic Acid. [Accessed on 8th July 2022] https://wellonapharma.com/product/finished/cefuroxime-and-potassium-clavulanate-tablets

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count
  • Chest X-ray

PRODUCT DETAILS

    Country Of Origin
    India
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

CEFSAFE CV 500 Tablet 10's

CEFSAFE CV 500 Tablet 10's Mkt: Khandelwal Laboratories Pvt Ltd

M.R.P.: Rs.422.06
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