Carpine Injection 1ml

Glaucoma Rx required
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Best Price*  ₹ 37.42
MRP ₹46.77
(Inclusive of all taxes) * Mkt: Intas Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

CARPINE contains pilocarpine which belongs to the group of medicines called miotic agents. It is used to induce prompt miosis (constriction or shrinkage of the pupil) during a cataract surgery with intraocular lens implant. Pilocarpine works by reducing the size of your pupil. It induces miosis by promoting contraction of the iris and pupillary sphincter muscles also improves the drainage of aqueous humor.

Your doctor will regularly check your eyes before and during treatment with pilocarpine, particularly if you have had any eye disorders. Do not wear soft contact lenses while using this medicine. Remove your lenses before applying this medicine. This medicine is only meant for ophthalmic use. Patients using CARPINE should be advised to avoid alcohol consumption during this therapy. This medicine is generally safe and is well tolerated. However, if you experience any undesirable effects after using this medicine, contact your doctor immediately.

Do not use this medicine if you are suffering from certain eye conditions where the constriction of the pupil should be avoided (such as inflammation of the iris, anterior uveitis, narrow angle glaucoma or secondary glaucoma). Before using this medicine, inform your doctor if you are pregnant or breast feeding as a precaution. This medicine should be used with caution in patients having lung or heart disease and in children under 18 years of age. Proper dose titration and careful monitoring are required in such patients.

USES OF CARPINE

  • Induce miosis during a cataract surgery

HOW CARPINE WORKS

Pilocarpine is a muscarinic receptor agonist. Ophthalmic administration of pilocarpine produces miosis by inducing the contraction of the ciliary muscles and pupillary sphincter muscles of the eyes. In addition to that, it also reduces the pressure within the eyeball by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.

DIRECTIONS FOR USE

This medicine will be given to you only by a doctor or an eye specialist into the eye cavity (intracameral) as an injection. It is for ophthalmic use only. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF CARPINE

COMMON

  • sensation of burning, itching and stinging in and around the eyes
  • eye discomfort or redness
  • blurred vision
  • headache or brow ache

HOW TO MANAGE SIDE EFFECTS

Eye itching, burning or stinging:

Close your eyes and relax. Place an ice pack on top of your eyes for few minutes. Avoid watching mobile phone, system, laptops or any other light sources which might irritate your eyes. If the symptom still persists or worsens, contact your doctor.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your doctor to recommend a painkiller.

Blurred vision:

This happens immediately after putting the medicine and is usually temporary. Wait until your vision becomes clear before driving or using machines.

WARNING & PRECAUTIONS

PREGNANCY

CARPINE should be used with caution in pregnant women. Consult your doctor before taking.

BREASTFEEDING

CARPINE should be used with caution in breastfeeding women. Consult your doctor before taking.

DRIVING AND USING MACHINES

Do not drive or operate any tools or machines, if you experience blurred vision or difficulty in seeing in the dark.

ALCOHOL

Avoid consumption of alcohol while using this medicine.

ALLERGY

Do not use this medicine if you are allergic to pilocarpine or other mitotic agents.

LUNGS

CARPINE should be used with caution in patients having bronchial asthma. Consult your doctor for advice.

HEART DISEASE

CARPINE should be used with caution in patients having heart disease (e.g. heart failure or high blood pressure). Consult your doctor for advice.

INTERACTIONS

Talk to your doctor, if you are taking,

  • antihistamines (used to treat allergies) such as naphazoline, olopatadine
  • anticholinergics (medicines used to inhibit muscle contractions) such as neostigmine, physostigmine
  • mydriatics (medicines used to enlarge your pupil) e.g. atropine
  • medicines used to dry up the saliva in your mouth (such as atropine and phenylephrine)
  • medicines used to treat Parkinson’s disease (e.g. procyclidine and trihexyphenidyl)
  • pethidine (used to treat pain)
  • orphenadrine (used to relieve pain from sprains, strains or muscle injury)
  • medicines used to treat depression (e.g. amitriptyline, fluoxetine, sertraline)
  • phenothiazines (used to treat mental illness) such as chlorpromazine
  • medicines used for high blood pressure (e.g. guanethidine)
  • other miotic agents (e.g. phospholine iodide, carbachol)
  • corticosteroids (used to treat pain or inflammation) creams or pills e.g. prednisolone

SYNOPSIS

Drug :   Pilocarpine
Pharmacological Category :   Miotic agent, Muscarinic receptor agonist
Therapeutic Indication :   Miosis induction
Dosage Forms :   Tablet, Eye drops, Ophthalmic solution (Injection)

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT CARPINE

Can I drink alcohol while using CARPINE?

No. Avoid consumption of alcohol while taking this medicine, as it may result in unwanted side effects.

What happens when I take too much of CARPINE?

This medicine will be given only by an eye specialist or a doctor. So, it is unlikely that you receive too much. However, if you experience any undesirable effects after administration, inform your doctor.

Can CARPINE be given to children?

Yes. This medicine can be given to children. Proper dose titration and careful monitoring are required in such patients.

REFERENCES

1. KD. Tripathi. Cholinergic System and Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 104-105.

2. Joan Heller Brown and Nora Laiken. Muscarinic receptor agonist and antagonists. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 224.

3. Gerald G. Briggs and Roger K. Freeman. P. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 3142-3143.

4. W P Boger 3rd, R F Steinert, C A Puliafito, D Pavan-Langston. Clinical trial comparing timolol ophthalmic solution to pilocarpine in open-angle glaucoma. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. July 1978. [Accessed 2nd January 2020] https://pubmed.ncbi.nlm.nih.gov/354397/

5. Victoria Panarese, Majid Moshirfar. Pilocarpine. NCBI; PMC US National Library of Medicine, National Institute of Health. March 2020. [Accessed 2nd January 2020] https://www.ncbi.nlm.nih.gov/books/NBK556128/

6. Sunways India Pvt Ltd. CARPINOL - Pilocarpine Nitrate 0.5% Ophthalmic Solution. Sunways.com. [Accessed 2nd January 2021] http://www.sunways.com/Products/SunwaysProducts/Carpinol.html

7. Laboratoire Chauvin. Electronic Medicines Compendium (EMC); [Revised on March 2019] [Accessed 2nd January 2021] https://www.medicines.org.uk/emc/files/pil.1375.pdf

8. Martindale Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC); [Revised on April 2016] [Accessed 2nd January 2021] https://www.medicines.org.uk/emc/files/pil.3398.pdf

PRODUCT DETAILS

    Net Qty
    1 N
    Ingredient
    PILOCARPINE 0.5%
    Hsn Code
    30044090
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