Bharglob 16.5% Injection 2ml

Immunoglobulins Rx required
OUT OF STOCK

Best Price*  ₹ 740.93
MRP ₹926.16
(Inclusive of all taxes) * Mkt: Bharat Serums & Vaccines Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

BHARGLOB 16.5% contains Human normal immunoglobin which belongs to the group of medicines called Immunoglobins. It supplements our body with sufficient antibodies (agents which are responsible for providing immunity) that are required to fight against various infections.

BHARGLOB 16.5% is primarily used in patients with a poor immune system and in patients who cannot produce enough antibodies on their own. It can prevent or treat various infections such as hepatitis, mumps, measles, poliomyelitis, varicella, rubella, oral herpetiform lesions especially in patients with low immunity and in patients who are suspectable to stomach and respiratory tract infections. It can also be used to treat various auto-immune disorders in both adults and in children (aged 2 years or older).

Human Normal Immunoglobulin contains antibodies (IgG) derived from the blood of healthy donors. Following administration, it supports our immune system by supplementing our body with sufficient antibodies that are required to fight against various infections. It can also modulate the functions of immune system in case of autoimmune disorders.

Do not receive BHARGLOB 16.5% if you are allergic to immunoglobulins or if you are deficient in a type of an immunoglobulin called IgA. You must also inform your doctor if you have blood clotting problems, any untreated infections, or any problems in your blood vessels.

Before receiving BHARGLOB 16.5% inform your doctor if you have diabetes or any kidney, or heart problems as a precaution. BHARGLOB 16.5% should be used in pregnant and breastfeeding women only if it is considered necessary by the physician.

The most common side effects of BHARGLOB 16.5% are headache, inflammation at the injection site, mouth ulcers, stomach problems, or joint pain. Contact your doctor if any of these side effect worsens.

USES OF BHARGLOB 16.5%

It is used in both adults and in children (aged 2 years or older) to:

  • Treat or prevent serious infections (such as mumps, measles, rubella, hepatitis, poliomyelitis, varicella or oral herpetiform lesions)
  • Treat immune disorders (such as congenital or acquired agammaglobulinemia or hypogammaglobulinemia or Wiskott-Aldrich syndrome)

HOW BHARGLOB 16.5% WORKS

BHARGLOB 16.5% supports our immune system by supplementing our body with sufficient antibodies that are required to fight against various infections. It can also regulate the functions of immune system and reduces the risk of autoimmune disorders.

DIRECTIONS FOR USE

BHARGLOB 16.5% will be administered to you only by a doctor or a nurse into the muscles (intramuscularly) or under the skin (subcutaneously). It can also be self-administered by yourself. Self-administration is advised only when your doctor or nurse has trained you properly regarding the administration of BHARGLOB 16.5%. Do not inject BHARGLOB 16.5% without consulting your doctor.

SIDE EFFECTS OF BHARGLOB 16.5%

COMMON

  • pain, swelling, redness, burning or itching at the site of injection
  • headache or migraine (severe headache)
  • stomach pain, diarrhoea, nausea, and vomiting
  • mouth ulcers
  • feeling dizzy, tired, or anxious
  • sensation of tingling
  • shivering
  • wheezing, asthma attack
  • chest pain or chest discomfort
  • muscle or joint stiffness, joint pain
  • skin rash, sweating, itchy skin, skin flushing

Contact your doctor immediately if you experience any of the following side effects while receiving BHARGLOB 16.5%:

  • signs of a brain infection called aseptic meningitis syndrome (such as nausea, vomiting, severe headache, neck stiffness, drowsiness, fever, fear to look lights (photophobia))
  • signs of blood clots (such as pain, swelling and unusual warmth of the hands and legs, sudden shortness of breath with chest pain, worsening on deep breathing, numbness, or weakness on one side, difficulty in speaking or confusion)
  • signs of allergic reactions (such as sudden fall in blood pressure or shock, dizziness, light-headedness, feeling faint while standing, cold hands and feet, abnormal heartbeat, chest pain, or blurred vision)
  • signs of acute lung injury (such as build-up of fluid in the lungs, severe difficulty in breathing, bluish discoloration of the skin, abnormally low level of oxygen in the blood, and decrease in blood pressure with fever)
  • headache, chills, flushing, muscle pain, lower back pain, wheezing, rapid heartbeat, nausea, or low blood pressure

HOW TO MANAGE SIDE EFFECTS

Pain, swelling, redness, burning or itching at the site of injection:

Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.

Mouth ulcers:

Avoid eating spicy foods. Drink plenty of fluids. Consult your doctor for a suitable oral pain-relieving gel containing lignocaine, triamcinolone, or choline salicylate.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

WARNING & PRECAUTIONS

PREGNANCY

BHARGLOB 16.5% should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before receiving it.

BREASTFEEDING

BHARGLOB 16.5% should be used in breastfeeding women only if it is considered necessary by the physician. Therefore, consult your doctor before receiving it.

DRIVING AND USING MACHINES

Do not drive or handle heavy machines if you experience dizziness after receiving BHARGLOB 16.5%.

ALCOHOL

Avoid consumption of alcohol while receiving BHARGLOB 16.5%.

ALLERGY

Do not receive BHARGLOB 16.5% if you are allergic to Human normal immunoglobin or other immunoglobins.

OTHERS

BHARGLOB 16.5% is not recommended for use if you:

  • are deficient in immunoglobulin A (first line antibodies that protects our body from infections)
  • have blood clot disorders
  • have high viscous or thick blood
  • are immobile or bedridden for a long time

Before receiving BHARGLOB 16.5% inform your doctor if you:

  • are going to have any blood test
  • have diabetes

Use in pediatrics:

BHARGLOB 16.5% should be used with caution in children and adolescents (aged 2 years or older). Therefore, consult your doctor before receiving.

Use in geriatrics:

BHARGLOB 16.5% should be used with caution in elderly patients (65 years or above).  Therefore, consult your doctor before receiving.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving BHARGLOB 16.5%, inform your doctor if you are taking:

  • loop diuretics (medicines used to increase urine output and to reduce blood pressure) Ex. furosemide
  • live-attenuated viral vaccines (Ex. MMR, chickenpox, varicella)

Overdosage:

BHARGLOB 16.5% will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unpleasant symptoms after receiving BHARGLOB 16.5%.

SYNOPSIS

Drug :   Human Normal Immunoglobulin
Pharmacological Category :   Immunoglobulins
Therapeutic Indication :   Immune deficiency States
Dosage Forms :   Injection

MORE INFORMATION

  • Keep BHARGLOB 16.5% out of reach of children
  • Store BHARGLOB 16.5% in a refrigerator (2-8°C)

FAQs ABOUT BHARGLOB 16.5%

What is BHARGLOB 16.5%?

BHARGLOB 16.5% is an immunoglobulin (antibody) used to treat immune deficiency states and auto-immune diseases both in adults and in children (aged 2 years or older).

How to take BHARGLOB 16.5%?

BHARGLOB 16.5% will be administered to you only by a doctor or a nurse into the muscles (intramuscularly) or under the skin (subcutaneously). It can also be self-administered by yourself. Self-administration is advised only when your doctor or nurse has trained you regarding the administration of BHARGLOB 16.5%. Do not inject BHARGLOB 16.5% without consulting your doctor.

What are the uses of BHARGLOB 16.5%?

BHARGLOB 16.5% improves immune functions in patients having weak immune system. It can also be used to treat various inflammatory auto-immune disorders in both adults and in children.

Is BHARGLOB 16.5% injection safe?

BHARGLOB 16.5% should be used under medical supervision. It may cause few side effects like are pain and swelling at the site of injection, mouth ulcers, nausea, vomiting, stomach problems, headache, muscle pain, joint pain, or body pains. Consult your doctor if any of the side effect worsens.

What does BHARGLOB 16.5% do?

BHARGLOB 16.5% supports our immune system by supplementing our body with sufficient antibodies that are required to fight against various infections. It can also regulate the functions of immune system and reduces the risk of autoimmune disorders.

What are the precautions to be known before receiving BHARGLOB 16.5%?

Before receiving BHARGLOB 16.5% inform your doctor if you are deficient in a type of immunoglobulin called IgA. You must also inform your doctor if you have diabetes, kidney, or heart problems as a precaution. Do not get yourself vaccinated with any viral vaccines (like MMR, chickenpox, or varicella) while receiving BHARGLOB 16.5%. Tell your doctor immediately if you experience any allergic reactions or severe headache with flushing and muscle pain while receiving BHARGLOB 16.5%.

Can I stop receiving BHARGLOB 16.5% by my own once the symptoms subside?

Do not stop receiving BHARGLOB 16.5% without consulting your physician, as sudden discontinuation of BHARGLOB 16.5% may reduce your immune functions once again. If you feel better after receiving BHARGLOB 16.5%, it means that it is working for you. If you wish to stop BHARGLOB 16.5%, consult your doctor for advice.

How long does it take for BHARGLOB 16.5% to show its effects?

It may take a few weeks (3-5 weeks) for BHARGLOB 16.5% to show the results. However, this duration may vary from patient to patient depending upon their health condition. Consult your doctor if you cannot see any improvement in your condition even after using BHARGLOB 16.5% for a prolonged period.

Can pregnant women receive BHARGLOB 16.5%?

BHARGLOB 16.5% should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.

REFERENCES

1. KD. Tripathi. Vaccines and Sera. Miscellaneous Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 926.

2. Roger H. Kobyaschi Clinical Efficacy, Safety and Tolerability of a New Subcutaneous Immunoglobulin 16.5% (Octanorm [Cutaquig®]) in the Treatment of Patients with Primary Immunodeficiencies. Frontier’s. February 2019. [Accessed on 23rd June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369354/pdf/fimmu-10-00040.pdf

3. Bio Products Laboratory Ltd. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 4th April 2022] https://www.medicines.org.uk/emc/files/pil.11462.pdf

4. Octapharma Australia Pty. Ltd, Human normal immunoglobin May 2021, [Accessed on 4th April 2022] https://www.tga.gov.au/sites/default/files/auspar-human-normal-immunoglobulin-210621-pi.pdf

5. Octapharma Pharmazeutika Produktionsges. m.b.H [Revised on October 2021] [Accessed on 4th April 2022] https://www.fda.gov/media/119234/download

6. Bharat Serums and Vaccines Limited. [Accessed on 4th April 2022] https://www.bharatserums.com/assets/pdf/products/Bharglob.pdf

PRODUCT DETAILS

    Net Qty
    1 N
    Ingredient
    HUMAN NORMAL IMMUNOGLOBULIN 16.5%
    Hsn Code
    30049069
DISCLAIMER

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