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INTRODUCTION
BETNESOL ORAL DROPS contains Betamethasone, which belongs to the group of medicines called Corticosteroids. It is used to treat bronchial asthma, severe hypersensitivity reactions, anaphylaxis, autoimmune diseases (connective tissue disorders, rheumatoid arthritis, bullous pemphigoid, idiopathic thrombocytopenic purpura, etc.), inflammatory diseases of kidneys (minimal change nephrotic syndrome, acute interstitial nephritis), inflammatory diseases of intestine (ulcerative colitis, Crohn’s disease), sarcoidosis, rheumatic carditis, haemolytic anaemia (autoimmune), certain cancers, and immunosuppression in transplantation.
BETNESOL ORAL DROPS is not recommended to use in patients having infections in which treatment with antibiotics is not started and live virus immunization. Before taking BETNESOL ORAL DROPS, inform your doctor if you have liver, heart, or lung diseases, chickenpox or shingles, osteoporosis, high blood pressure, epilepsy, glaucoma (increased pressure within the eye), tuberculosis, peptic ulcers, or diabetes.
BETNESOL ORAL DROPS should be used with caution among women who are pregnant or breastfeeding. BETNESOL ORAL DROPS should be used with caution in children, adolescents, and elderly patients. Contact your doctor if feel any unusual symptoms while taking BETNESOL ORAL DROPS.
USES OF BETNESOL ORAL DROPS
Treats:
- bronchial asthma
- severe hypersensitivity reactions, anaphylaxis
- autoimmune diseases (connective tissue disorders, rheumatoid arthritis, bullous pemphigoid, idiopathic thrombocytopenic purpura, etc.)
- inflammatory diseases of kidneys (minimal change nephrotic syndrome, acute interstitial nephritis)
- inflammatory diseases of intestine (ulcerative colitis, Crohn’s disease)
- sarcoidosis
- rheumatic carditis
- haemolytic anaemia (autoimmune)
- certain cancers (malignant lymphoma, multiple myeloma)
- immunosuppression in transplantation
HOW BETNESOL ORAL DROPS WORKS
BETNESOL ORAL DROPS inhibits certain chemical pathways in the body which reduces the formation of substances (arachidonic acid) that causes pain. It also enhances anti-inflammatory genes like interleukin 10. Therefore, helping in reducing pain and inflammation.
DIRECTIONS FOR USE
Take BETNESOL ORAL DROPS as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, weight, and health condition.
SIDE EFFECTS OF BETNESOL ORAL DROPS
RARE
Stop taking BETNESOL ORAL DROPS and contact your physician immediately if you experience any of the following side effects:
- unusual symptoms or worsening of the existing condition
WARNING & PRECAUTIONS
PREGNANCY
BETNESOL ORAL DROPS should be used with caution in pregnant women only if advised by the doctor as there is lack of data. Consult your doctor before taking BETNESOL ORAL DROPS.
BREASTFEEDING
BETNESOL ORAL DROPS should be used with caution in breastfeeding women under careful observation of the doctor as it passes through breast milk. Consult your doctor before taking it.
LIVER
BETNESOL ORAL DROPS should be taken with caution in patients with liver diseases. Consult your doctor before taking BETNESOL ORAL DROPS.
ALLERGY
Do not take BETNESOL ORAL DROPS if you are allergic to Betamethasone or any of the other ingredients of this medicine.
LUNGS
BETNESOL ORAL DROPS should be taken with caution in patients with lung diseases such as asthma. Consult your doctor before taking BETNESOL ORAL DROPS.
HEART DISEASE
BETNESOL ORAL DROPS should be used with caution in patients with heart diseases such as congestive heart failure. Consult your doctor taking BETNESOL ORAL DROPS.
OTHERS
BETNESOL ORAL DROPS is not recommended for use if you have:
- infections in which treatment with antibiotics is not started
- undergone a live vaccine immunization
Before taking BETNESOL ORAL DROPS, inform your doctor if you have:
- stomach or duodenal ulcers
- tuberculosis (TB)
- epilepsy (fits)
- glaucoma (raised eye pressure)
- osteoporosis (thinning of the bones)
- chickenpox, shingles, or measles, or having contact with a person having these
- diabetes
- underactive thyroid gland
- myasthenia gravis
- steroid psychosis (confusion and agitation following high doses of corticosteroids)
- steroid myopathy (weakness of muscles of upper and lower limbs and neck)
- high blood pressure
Use in pediatrics:
BETNESOL ORAL DROPS should be used with caution in children and adolescents. Your doctor will decide the correct dose and duration of BETNESOL ORAL DROPS depending upon your child’s age, diseases condition and body weight. Consult your child’s doctor before taking BETNESOL ORAL DROPS.
Use in geriatrics:
BETNESOL ORAL DROPS should be used with caution in elderly patients as it may cause side effects serious consequences of the common side effects such as osteoporosis, hypertension, diabetes, susceptibility to infection and thinning of the skin. Consult your doctor before taking BETNESOL ORAL DROPS.
INTERACTIONS
A. Drug-Drug interactions:
Before taking BETNESOL ORAL DROPS, inform your doctor if you are taking any of the following medicine:
- medicines used for myasthenia gravis (Ex. pyridostigmine)
- medicines used to treat pain and inflammation such as non-steroidal anti-inflammatory drugs (Ex. ibuprofen), salicylates (Ex. aspirin)
- medicines used for thinning of the blood (Ex. warfarin)
- medicines used to treat tuberculosis (Ex. rifampicin, rifabutin)
- medicines used to treat epilepsy (Ex. carbamazepine, phenytoin)
- medicines used to treat HIV (Ex. ritonavir, cobicistat)
- medicines used as oral contraceptives (pills) (Ex. estradiol)
- medicines used to treat fungal infections (Ex. itraconazole)
- radiopaque dye used in Xray of gall bladder (Ex. cholecystography x-ray media)
- medicines used to treat hypotension (low blood pressure) (Ex. ephedrine)
Overdosage:
If you or anyone else accidentally take too much of BETNESOL ORAL DROPS, consult your doctor immediately or visit the nearby hospital. In cases of chronic overdosage, symptoms of hypercortisolism (extra cortisol in body) may occur such as thinning of skin, easy bruising, weight gain, and rounding of face.
SYNOPSIS
| Drug | : | Betamethasone |
| Pharmacological Category | : | Corticosteroids |
| Therapeutic Indication | : | Inflammation-related diseases like |
| Dosage Forms | : | Tablet, Gel, Cream, Ointment, Lotion, Oil, Oral drops, Eye/Ear drops, Injection |
MORE INFORMATION
- Keep BETNESOL ORAL DROPS out of reach of children
- Store BETNESOL ORAL DROPS at a temperature, not more than 30°C
FAQs ABOUT BETNESOL ORAL DROPS
What if I forget to take a dose of BETNESOL ORAL DROPS?
If you forget a dose of BETNESOL ORAL DROPS, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed dose as this may increase the chances of developing side effects.
Is it safe to use BETNESOL ORAL DROPS in pregnancy and breastfeeding?
BETNESOL ORAL DROPS should be used with caution among women who are pregnant or breastfeeding. Consult your doctor before taking BETNESOL ORAL DROPS.
When BETNESOL ORAL DROPS is not recommended?
BETNESOL ORAL DROPS is not recommended to use in patients having infections in which treatment with antibiotics is not started. Consult your doctor before taking BETNESOL ORAL DROPS.
Is it safe to use BETNESOL ORAL DROPS in patients having diabetes?
BETNESOL ORAL DROPS is a corticosteroid which has tendency to inhibit glucose utilization and reduce glucose uptake which may worsen the condition of diabetes. Consult your doctor before using it.
Can I stop taking BETNESOL ORAL DROPS on my own?
It is very important to keep taking BETNESOL ORAL DROPS till the time your doctor has prescribed it to you. Do not stop taking it on your own even if you feel better as corticosteroids must be stopped gradually. Ask for your doctor’s advise if you wish to discontinue the use of BETNESOL ORAL DROPS due to any reason.
What precautions shall I take while on treatment with BETNESOL ORAL DROPS?
While getting treated with BETNESOL ORAL DROPS, keep away from patients having chicken pox or shingles and even tell your doctor beforehand if you yourself had them. Contact your doctor if you feel you got in touch with someone having these as taking BETNESOL ORAL DROPS may worsen the condition.
Is BETNESOL ORAL DROPS a steroid?
Yes. BETNESOL ORAL DROPS is potent steroid which inhibits certain chemical pathways in the body which reduces the formation of substances (arachidonic acid) that causes pain. It also enhances anti-inflammatory genes like interleukin 10. Therefore, helping in reducing pain and inflammation.
REFERENCES
1. KD Tripathi. Corticosteroids. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 289.
2. Komal Gaur and Barna Ganguly. Effect of Single Dose Betamethasone Administration in Pregnancy on Maternal and Newborn Parameters. Journal of Clinical and Diagnostic Research. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. May 2017 [Accessed on 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483699/
3. Peter T Daley-Yates, Alison C Price, Jonathan R Sisson, Adrian Pereira, and Nigel Dallow. Beclomethasone dipropionate: absolute bioavailability, pharmacokinetics and metabolism following intravenous, oral, intranasal and inhaled administration in man. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. May 2001 [Accessed on 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014471/
4. Betamethasone. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in August 2022] [Accessed on 18th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone
5. GlaxoSmithKline Pharmaceuticals Limited. Betnesol oral drops [Revised in January 2022] [Accessed on 19th August 2022] https://india-pharma.gsk.com/media/6344/betnesol-oral-drops.pdf
USEFUL DIAGNOSTIC TESTS
- Absolute Eosinophil Count
- Peripheral Smear Examination
- Total IgE
AUTHOR DETAILS
Written By Dr. Dhivakaran R, BDS
Last updated on 11 Oct 2022 | 10:31 AM(IST)
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