INTRODUCTION

BETAGEL GEL contains Betamethasone, which belongs to the group of medicines called Corticosteroids. It is used to reduce the redness and itchiness of certain skin problems like eczema (patches of rough and scaly skin with blisters), psoriasis (scales and itchy dry patches due to build-up of skin cells), and dermatitis (inflammation of the skin).

Do not smoke or go near naked flames after applying BETAGEL GEL, as it is inflammable. BETAGEL GEL is not recommended to use in patients having several skin conditions like acne, severe flushing of skin on and around the nose (rosacea), spotty red rash around the mouth (perioral dermatitis), itching around the back passage or private parts, infected skin, and itchy skin which is not inflamed.

Before using BETAGEL GEL, inform your doctor if you have a chronic leg ulcer, psoriasis or infection of the skin. BETAGEL GEL should be used with caution among women who are pregnant or breastfeeding. BETAGEL GEL is not recommended for use in children less than 1 year of age.

The most common side effects of using BETAGEL GEL are application site reactions like the feeling of burning, pain, irritation or itching. Contact your doctor if any of the above symptoms worsen.

USES OF BETAGEL GEL

It reduces the redness and itchiness of certain skin problems like:

• eczema
• psoriasis
• dermatitis

HOW BETAGEL GEL WORKS

BETAGEL GEL works by acting inside skin cells and preventing the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any kind of allergens, such chemicals are released normally.

DIRECTIONS FOR USE

Always apply BETAGEL GEL as directed by your physician. It is for external use only. Apply a thin layer of BETAGEL GEL to the affected area. Avoid applying this medicine around your eyes, including your eyelids. Your doctor will decide the correct dose and duration of BETAGEL GEL depending upon your age, weight and health condition.

SIDE EFFECTS OF BETAGEL GEL

HOW TO MANAGE SIDE EFFECTS

Skin irritation

Avoid hot bathing because hot water can irritate your skin further. Do not scratch the affected area. Use comfortable clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptoms don’t improve or worsen.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before using BETAGEL GEL, inform your doctor if you are taking any of the following medicine:

• medicine used to treat Human Immunodeficiency Virus (HIV) (Ex. ritonavir)
• medicine used to treat fungal infection (Ex. itraconazole)

Overdosage

If you or anyone else accidentally ingests or use too much of BETAGEL GEL, consult your doctor immediately or visit the nearby hospital as it can make you ill.

SYNOPSIS

MORE INFORMATION

• Keep BETAGEL GEL out of reach from children
• Store at a temperature not more than 25°C

FAQs ABOUT BETAGEL GEL

How to use BETAGEL GEL?

Always apply BETAGEL GEL as directed by your physician. It is for external use only. Apply a thin layer of BETAGEL GEL to the affected area. Treated areas on the face should not be covered with a plaster or bandage. Do not use this medicine on your face for more than 5 days. Avoid applying this medicine around your eyes, including your eyelids.

What if I forget to use a dose of BETAGEL GEL?

If you forget a dose of BETAGEL GEL, apply it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and apply the next scheduled dose at the prescribed time.

Is it safe to use BETAGEL GEL during pregnancy and breastfeeding?

GBNKEYWORD] should be used with caution in pregnant women and breastfeeding women unless considered clearly necessary. Consult your doctor before using BETAGEL GEL.

When BETAGEL GEL is not recommended?

BETAGEL GEL is not recommended to use in patients having several skin conditions like acne, severe flushing of skin on and around the nose (rosacea), spotty red rash around the mouth (perioral dermatitis), itching around the back passage or private parts, infected skin, and itchy skin which is not inflamed. It is also not recommended to use in children below 1 year of age. Please consult your doctor before using BETAGEL GEL.

Is BETAGEL GEL safe for use by children?

BETAGEL GEL is generally not recommended for use in children under 1 year of age. Consult with your child’s doctor before using BETAGEL GEL.

Does BETAGEL GEL cause skin irritation?

Yes. Skin irritation is the most common side effect of BETAGEL GEL. Avoid hot baths, as hot water can irritate your skin further. Do not scratch the affected area. Use comfortable clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptoms get worse or persist.

Can I stop using BETAGEL GEL on my own?

It is very important to keep using BETAGEL GEL till the time your doctor has prescribed it to you. Do not stop taking it on your own even if your symptoms lessen and you feel better. If you stop using BETAGEL GEL suddenly, your condition may get worse. Consult with your doctor if you wish to discontinue using BETAGEL GEL.

Can I start using BETAGEL GEL in case of a reoccurrence of my condition?

If you experience a recurrence of your condition shortly after stopping treatment with BETAGEL GEL, within 2 weeks, do not restart using BETAGEL GEL without consulting a doctor. If your condition has resolved and on recurrence the redness extends beyond the initial affected area and there is a burning sensation, please seek medical advice before restarting treatment.

What precautions should be taken while using BETAGEL GEL?

Do not smoke or go near naked flames while getting treated with BETAGEL GEL due to the risk of severe burns. Fabric (clothing, bedding, dressing, etc.) that has been in contact with BETAGEL GEL burns more easily and is a serious fire hazard.

REFERENCES

1. KD Tripathi. Corticosteroids. Drugs Essentials of medical pharmacology. 7th edition. 2013. Page – 289.

2. Sanaa A El-Gizawy, Maha Fadel, Basma Mourad, and Fatma El-zahraa Abd Elnaby. Betamethasone Dipropionate for Treatment of Localised Plaque Psoriasis. International Journal of Pharmacy and Pharmaceutical Sciences. Research gate. August 2017 [Accessed on 18th August 2022] https://www.researchgate.net/publication/318834216

3. Betamethasone. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in August 2022] [Accessed on 18th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone

4. Merck & Co., Inc. US Food and Drug Administration. [Revised in May 2019] [Accessed on 18th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/018741s040lbl.pdf

5. Glaxo Wellcome UK Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 18th August 2022] https://www.medicines.org.uk/emc/files/pil.930.pdf

6. Merck Canada Inc. [Revised in May 2020] [Accessed on 18th August 2022] https://pdf.hres.ca/dpd_pm/00057419.PDF

7. Glaxo Wellcome Operations. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 18th August 2022] https://www.medicines.org.uk/emc/files/pil.932.pdf

8. MIMS. Diprovate-RD (beclomethasone). [Accessed on 18th August 2022] https://www.mims.com/india/drug/info/diprovate-rd

USEFUL DIAGNOSTIC TESTS

• Absolute Eosinophil Count
• Peripheral Smear Examination
• Total IgE