INTRODUCTION

Aplazar Tablet is a nutritional supplement which is used for the treatment of chronic kidney disease patients on conservative management therapy (CKD stage I, II, III). It contains alfa ketoanalogues as active ingredients that delay the progression of CKD.

Alfa ketoanalogues work by allowing intake of essential amino acids and decreasing the amino-nitrogen intake. They also decrease urea formation, thus decreasing the accumulation of uraemic toxins and reducing kidney damage.

Always take Aplazar Tablet as advised by your physician. Do not take if you have high blood calcium levels or disturbed amino acid metabolism. It should be taken during meals to provide proper absorption and metabolism into corresponding amino acids.

KEY COMPOSITION

• Calcium-3 methyl-2-oxovalerate
• Calcium-4 methyl-2-oxovalerate
• Calcium-3 methyl-2-oxobutyrate
• Calcium-2-oxo-3-phenylpropionate
• Calcium-DL-2-hydroxy-4(-(methylthio)-butyrate
• L-Lysine Acetate
• L-Threonine
• L-Tryptophan
• L-Histidine
• L-Tyrosine

THERAPEUTIC USES OF APLAZAR TABLET

Used to

• treat chronic kidney disease patients on conservative management therapy (CKD stage I, II, III)
• delay the progression of kidney disease in combination with very low/low protein diet

SIDE EFFECTS OF APLAZAR TABLET

Consult your doctor if you experience any unusual side effects while taking Aplazar Tablet.

SAFETY ADVICE

• Always take Aplazar Tablet as advised by your physician
• Take 4-8 tablets thrice daily with meals or as directed by your doctor
• Do not exceed the recommended daily dosage
• Do not take if you are allergic to any of its ingredients
• Do not take if you have high blood calcium levels or disturbed amino acid metabolism
• Ask your doctor before giving it to pregnant women, breastfeeding women, infants, children, adolescents and elderly
• Inform your doctor about all the medicines that you take, including prescription, over-the-counter medications, and herbal supplements

MORE INFORMATION

• Keep out of reach of children
• Store at a temperature below 30°C

FAQs ABOUT APLAZAR TABLET

Q: What is the use of Aplazar Tablet?

A: Aplazar Tablet is a nutritional health supplement containing alfa ketoanalogues as active ingredients which is used to treat chronic kidney disease patients on conservative management therapy (CKD stage I, II, III) and delay the progression of kidney disease in combination with very low/low protein diet.

Q: How should I take Aplazar Tablet?

A:  Always take Aplazar Tablet as advised by your physician. Take 4-8 tablets thrice daily with meals. It should be taken during meals to allow optimum absorption and metabolism into the corresponding amino acids. Do not exceed the recommended daily dosage.

Q: Is Aplazar Tablet safe for pregnant women?

A: No experience has been made so far with the application of Aplazar Tablet in pregnancy. Please consult your doctor for advice before taking it.

Q: Can Aplazar Tablet be used for muscle wasting syndrome?

A: Aplazar Tablet is used to prevent muscle wasting syndrome, where alfa ketoanalogues supplementation favourably prevents skeletal muscle mass loss and fat mass gain in elderly patients with stage 4-5 CKD. Consult your doctor before taking it.

Q: Can Aplazar Tablet reduce the risk of undergoing long-term dialysis?

A: Aplazar Tablet reduces blood urea levels and helps prevent the progression of kidney disease, which delays the risk of undergoing long-term dialysis. Consult your doctor for further advice.

REFERENCES

1. https://www.steadfast.co.in/aplazar/#

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566830/

3. https://www.centaurpharma.com/downloads/2021/nephrology/NEFROGARD.pdf

4. https://www.septalyst.com/products/nephrology/renal_medicines/septasteril-nano-tab

5. https://www.fresenius-kabi.com/in/products/ketosteril