INTRODUCTION

ANOVATE CREAM is a combination of Beclomethasone, Lignocaine and Phenylephrine which belongs to the group of medicines called Corticosteroids, Anaesthetics and Nasal decongestants respectively. It is indicated in the treatment of pain and bleeding associated with anal fissures (a small tear in the lining of anus) and internal or external haemorrhoids, post haemorrhoidectomy (removal of piles) pain, minor degrees of proctitis (inflammation of lining of rectum).

Before using ANOVATE CREAM inform your doctor if you have any kidney, liver, heart or lung diseases. Consult with your doctor before using.

ANOVATE CREAM should be used with caution in pregnant and breast-feeding women. Consult with your doctor before using.

There is no information on the use of ANOVATE CREAM in children and elderly patients. Consult with your doctor before using.

The most common side effects of using ANOVATE CREAM are burning, irritation, itching and redness. Consult your doctor if any of these above side worsen or doesn’t improve.

USES OF ANOVATE CREAM

It is used to treat pain and bleeding associated with:

• anal fissures  
• internal or external haemorrhoids
• post haemorrhoidectomy (removal of piles)
• minor degrees of proctitis (inflammation of lining of rectum)

HOW ANOVATE CREAM WORKS

ANOVATE CREAM helps in treating conditions associated with piles where Beclomethasone acts by reducing the pain and inflammation (redness and swelling by blocking certain chemical messengers that are responsible for it). Lignocaine belongs to Anaesthetic agent which interferes the pain pathways by acting on the nerves and blocking them hence, causing pain relief. Phenylephrine belongs to decongestant that works by reducing the swelling.

DIRECTIONS FOR USE

Apply ANOVATE CREAM as advised by your physician. It is for rectal use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the medicine and wash your hands after applying.

SIDE EFFECTS OF ANOVATE CREAM

WARNING & PRECAUTIONS

PREGNANCY

ANOVATE CREAM should be used with caution in pregnant women. Consult your doctor before using it.

BREASTFEEDING

ANOVATE CREAM should be used with caution in breastfeeding women. Consult your doctor before using it.

ALLERGY

Do not use ANOVATE CREAM if you are allergic to Beclomethasone, Lignocaine or Phenylephrine or any other ingredients of this medicine.

INTERACTIONS

A. Drug – Drug interactions:

Before using ANOVATE CREAM, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

In case of accidental ingestion or too much application of ANOVATE CREAM, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep ANOVATE CREAM out of reach of children
• Store below 25°C

FAQs ABOUT ANOVATE CREAM

Q: What is ANOVATE CREAM and why is it prescribed?

A: It is a combination of Beclomethasone, Lignocaine and Phenylephrine which belongs to the group of medicines called Corticosteroids, Anaesthetics and Nasal decongestants respectively. It is indicated in the treatment of pain and bleeding associated with anal fissures (a small tear in the lining of anus) and internal or external haemorrhoids, post haemorrhoidectomy (removal of piles) pain, minor degrees of proctitis (inflammation of lining of rectum).

Q: Is it safe to use ANOVATE CREAM in pregnant and breast-feeding women?

A: ANOVATE CREAM should be used with caution in pregnant and breast-feeding women. Consult with your doctor before using.

Q: Does ANOVATE CREAM cause any side effects?

A: The most common side effects of using ANOVATE CREAM are burning, irritation, itching and redness. Ask for your doctor’s advice if any of these worsen or doesn’t improve.

Q: How to use ANOVATE CREAM?

A: Apply ANOVATE CREAM as advised by your physician. It is for rectal use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the medicine and wash your hands after applying.

Q: Can I stop using ANOVATE CREAM if I feel better?

A: Do not stop using ANOVATE CREAM on your own. Use it for as long as your doctor has prescribed it to you. If you wish to discontinue, ask for your doctor’s advice.

REFERENCES

1. K.D. Tripathi. Drugs Acting on ANS, Local Anesthetics, Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 133, 366 & 895.

2. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Beclomethasone. [Accessed on 11th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Beclomethasone

3. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Lidocaine. [Accessed on 11th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Lidocaine

4. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Phenylephrine. [Accessed on 11th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Phenylephrine

5. Sanofi India Ltd. Proctosedyl bd. [Revised in August 2021] [Accessed on 11th July 2022] https://www.sanofi.in/dam/jcr:e47683ec-ca27-475d-a4e0-b003166ec262/Proctosedyl%20BD%20API%20_new.pdf

6. Leeford Healthcare Ltd. Pilo Go Cream. Leeford. [Accessed on 11th July 2022] https://www.leeford.in/product/1290/pilo-go-cream

USEFUL DIAGNOSTIC TESTS

• Digital Rectal Examination

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 09 Jan 2023 | 11:27 PM(IST)