What is Amitriptyline Hydrochloride used for?
Amitriptyline Hydrochloride is used in the treatment of:
- Symptoms of depression;
- Bedwetting at night in children aged 6 years and above.
Amitriptyline Hydrochloride may also be prescribed for other conditions as determined by your doctor.
How does Amitriptyline Hydrochloride work?
Amitriptyline Hydrochloride belongs to a group of medicines called tricyclic antidepressants. Amitriptyline Hydrochloride alters the levels of chemicals in the brain and helps in relieving the symptoms of depression
How to take Amitriptyline Hydrochloride?
- The dosage of Amitriptyline Hydrochloride capsule and tablet depends on the age, weight and medical condition of an individual. Take Amitriptyline Hydrochloride as prescribed by your doctor.
- Amitriptyline Hydrochloride should be taken with or without food. Do not chew the tablet.
- Swallow the tablet with a glass of water.
- Amitriptyline Hydrochloride is not recommended for treatment of depression in children under 12 years of age.
- Amitriptyline Hydrochloride is not advised to be taken for treatment of bedwetting in children under 6 years of age.
- Do not discontinue Amitriptyline Hydrochloride without consulting a doctor.
- If you miss a dose of Amitriptyline Hydrochloride, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.
What should you do when you have taken an overdose of Amitriptyline Hydrochloride?
If you have taken an overdose of Amitriptyline Hydrochloride, please contact your doctor immediately.
Symptoms of overdose may include the following:
- Dry mouth and tongue
- Hot dry skin
- Pain in abdomen
- Fast regular heart beat
- Dilated pupils
- Breathing difficulty
- Difficulty in urination
- Uncontrolled eye movements
What are the drugs that interact with Amitriptyline Hydrochloride?
Drugs that interact with Amitriptyline Hydrochloride:
- Adrenaline, Ephedrine, Noradrenaline, Phenylephrine, Isoprenaline
- Amiodarone, Diltiazem, Disopyramide, Procainamide, Propafeone, Quinidine, Sotalol, Verapamil
- Apraclonidine, Brimonide
- Benzatropine, Dicyclomine, Doxyamine
- Carbamazepine, Phenobarbital
- Clozapine, Pimozide, Haloperidol, Chlorpromazine
- Entacapone, Selegiline
- Glyceryl trinitrate, Isosorbide dinitrate
- Guanethidine, Debrisoquine, Bethanidine, Clonidine
- Nefopam, Tramadol, Codeine, Dihydrocodeine
- Oral contraceptive pills
- Rifampin, Linezolid
This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.
What are the side effects of Amitriptyline Hydrochloride?
Most common side effects of Amitriptyline Hydrochloride are:
- Headache, Weight gain or loss
- Increased perspiration
- Urinary frequency
Please stop your tablets and contact your physician immediately if you have
- thoughts of suicide and there is worsening of your depression after some days of taking this medicine;
- allergic reactions (skin rash, hives, itching, swelling of face, mouth, tongue, lips, shortness of breath, swelling, collapse);
- low blood sodium levels;
- fever, chills, sore throat, ulcers in mouth, dry mouth;
- unusual bleeding;
- lack of control when urinating;
- dilatation of pupil;
- jaundice (yellowing of the skin and mucous membranes);
- increased sweating, ringing in ears;
- withdrawal symptoms (nausea, malaise, headache, sleep disturbances, irritability, restlessness, mania or hypomania).
This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.
What special precautions should be followed while taking Amitriptyline Hydrochloride?
Seek doctor’s advice before taking any other drug or herbal products while on Amitriptyline Hydrochloride.
You are advised not to take Amitriptyline Hydrochloride if
- it has passed the expiry date of the medicine printed on the pack.
- the foil or packaging is torn or shows signs of tampering or there is discolouration.
What should you tell your doctor before taking Amitriptyline Hydrochloride?
Tell your doctor if
- you are allergic to Amitriptyline Hydrochloride or other medicine from the same class.
- you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
- you have liver or kidney disease.
- you have a history of heart disease.
- you have any mental illness.
- you have periods of increased or exaggerated behavior (mania).
- you have glaucoma (increased pressure in the eye).
- you have eczema.
- you have taken MAO (monoamine oxidase) inhibitors within the previous 14 days for depression.
- you are at risk of heart disease or
- you have diabetes.
- you are planning a surgery or any procedure.
- you are pregnant or trying to conceive or are breastfeeding.
Frequently asked questions about Amitriptyline Hydrochloride
Amitriptyline Hydrochloride capsules and tablets should be stored at 25°C in a cool and dry place. Keep the medicine away from sunlight and out of the sight and reach of children.
No, you can have your normal diet unless advised by your doctor.
You may notice improvement in your symptoms usually after 4 weeks of starting treatment. Please consult your doctor for more information.
Amitriptyline Hydrochloride causes blurring of vision and dizziness. It is advisable not to drive while taking Amitriptyline Hydrochloride.
No, you are not advised to drink alcohol while taking Amitriptyline Hydrochloride, as the medicine can increase the effect of alcohol.
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.