ALOJA M Tablet 10's
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Introduction About ALOJA M TABLET
ALOJA M TABLET is used to manage diabetes mellitus when it cannot be adequately controlled by diet, exercise, and other anti-diabetic medicines such as metformin alone, insulin alone, or metformin and pioglitazone taken together. It is a combination of Alogliptin and Metformin, which belong to the group of medicines called Antidiabetic agents. It works by increasing the levels of insulin in the body after a meal, decreasing the amount of sugar made in the liver, and helping to control blood glucose levels effectively.
During management with ALOJA M TABLET, your doctor will check your kidney function at least once a year or more frequently if you are elderly and/or have worsening kidney function.
ALOJA M TABLET is not recommended for use if you have severe breathing difficulties, severely reduced kidney function, liver disease, or if you recently had a heart attack or have severe circulatory problems, including shock. Consult your doctor before taking it.
ALOJA M TABLET is not recommended for use if you are pregnant or breastfeeding. Consult your doctor before taking it. ALOJA M TABLET is not recommended for children and adolescents under 18 years due to the lack of data in these patients. Consult your doctor before taking it.
The most common side effects of taking ALOJA M TABLET are stomach pain, diarrhea, loss of appetite, nausea, and vomiting. Consult your doctor if any of the side effects worsen.
Uses Of ALOJA M TABLET
- To manage type II diabetes mellitus
How ALOJA M TABLET Works
ALOJA M TABLET effectively controls blood glucose levels, where alogliptin works by increasing the levels of insulin in the body after a meal and helps decrease the blood glucose levels. Metformin also helps to lower blood glucose by decreasing the amount of sugar made in the liver and helping insulin work more effectively.
How to use ALOJA M TABLET
Take ALOJA M TABLET with food or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition. Do not stop taking ALOJA M TABLET unless your doctor advises you to stop.
Side Effects Of ALOJA M TABLET
Common
- Stomach pain, diarrhea, indigestion, heartburn, loss of appetite, nausea, and vomiting
- Symptoms of low blood sugar (hypoglycemia) include trembling, sweating, anxiety, blurred vision, tingling lips, paleness, mood changes, or feeling confused
- Cold symptoms such as a sore throat, blocked nose, feeling tired, fever, chills, and dry cough
- Rash, itchy skin with or without hives
- Headache
- Metallic taste
Rare
Stop taking ALOJA M TABLET and consult your doctor immediately if you experience any of the following side effects:
- Symptoms of a serious allergic reaction (Stevens-Johnson syndrome), such as rash, hives (raised red patches on your skin), swelling of the face, lips, tongue, and throat that may cause difficulty breathing or swallowing. Other symptoms may include general itching and a feeling of heat, especially affecting the scalp, mouth, throat, palms of hands, and soles of feet
- Signs of bullous pemphigoid, such as blistering of the skin
- Symptoms of lactic acidosis include vomiting, abdominal pain, muscle cramps, a general feeling of not being well with severe tiredness, difficulty breathing, and reduced body temperature and heartbeat
How To Manage Side Effects
Diarrhea
Drink plenty of clear fluids, like water, diluted fruit juices, or oral rehydration solutions, to stay hydrated. Avoid caffeinated or alcoholic beverages, as they can worsen dehydration. Gradually take bland, low-fiber foods like bananas, rice, applesauce, and toast to help firm up stools. Probiotics, found in yogurt or supplements, may help restore the balance of gut bacteria. Practice good hand hygiene to prevent the spread of infection. Consult your doctor if diarrhea worsens.
Headache
Ensure adequate fluid intake, as dehydration can cause headaches. Maintain a consistent sleep schedule, aiming for 7-9 hours of quality sleep per night. Eat balanced meals at regular intervals to avoid blood sugar fluctuations that can trigger headaches. Practice relaxation techniques such as meditation, yoga, or deep breathing exercises to reduce stress levels. Engage in regular physical exercise, which can help reduce the frequency and severity of headaches. Apply a cold pack or warm compress to the forehead or neck to alleviate pain. Consult your doctor if a headache persists.
Hypoglycemia
Consume fast-acting carbohydrates such as glucose tablets, fruit juice, regular soda, or candy. Check your blood sugar level using a glucose meter after 15 minutes. If it remains low, consume another 15 grams of carbohydrates and recheck after another 15 minutes. Once blood sugar levels stabilize, eat a small meal or snack that includes both protein and carbohydrates to prevent further drops. Regularly monitor your blood sugar levels, especially if you have diabetes. Maintain a consistent eating schedule, avoid skipping meals, and carry snacks or glucose tablets for emergencies. If you frequently experience low blood sugar, consult with your doctor.
Indigestion
Avoid trigger foods such as fatty, spicy, or acidic items. Eating slowly, chewing food thoroughly, and avoiding lying down immediately after meals can improve digestion. Reduce stress through relaxation techniques like meditation, yoga, or deep breathing, which can alleviate symptoms. Maintaining a healthy weight, quitting smoking, and limiting alcohol consumption are also beneficial. Drinking plenty of water helps digestion. Engaging in regular physical activity can help keep the digestive system active and reduce stress, which may improve symptoms. Consult your doctor if indigestion persists.
Nausea And Vomiting
Stay hydrated with small sips of clear fluids like water, ginger ale, or electrolyte solutions. Avoid consuming large meals; instead, opt for bland, easy-to-digest foods. Ginger, peppermint, or chamomile tea may help soothe the stomach. Rest in a comfortable position, preferably with your head elevated, to ease symptoms. Consult your doctor if nausea and vomiting persist.
Skin rash Or Itching
Keep the affected area clean and dry and avoid scratching to prevent further irritation or infection. Apply calamine lotion to help reduce itching and inflammation. Applying cool compresses and wearing loose, breathable clothing can also provide relief. If the rash persists, consult your doctor.
Stomach Pain
Avoid spicy or fatty foods, caffeine, or alcohol that may exacerbate symptoms. Eat a bland diet consisting of easily digestible foods like rice, bananas, applesauce, and toast. Applying a heating pad or taking a warm bath can also help soothe abdominal muscles and alleviate discomfort. Drink plenty of fluids to stay hydrated but avoid excessive consumption to prevent further irritation. If stomach pain persists, consult your doctor.
Warning & Precautions
Pregnancy
ContraindicatedALOJA M TABLET is not recommended for use if you are pregnant. Consult your doctor before taking it.
Breastfeeding
ContraindicatedALOJA M TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
Driving and Using Machines
SafeALOJA M TABLET does not affect your ability to drive and use machines.
Alcohol
Consult your doctorAvoid excessive consumption of alcohol while taking ALOJA M TABLET, as it may increase the risk of lactic acidosis.
Kidney
ContraindicatedALOJA M TABLET is not recommended for use if you have severely reduced kidney function. Consult your doctor before taking it.
Liver
ContraindicatedALOJA M TABLET is not recommended for use if you have liver disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take ALOJA M TABLET if you are allergic to alogliptin, metformin, or any of the other ingredients of this medicine.
Lungs
ContraindicatedALOJA M TABLET is not recommended for use if you have severe breathing difficulties. Consult your doctor before taking it.
Heart Disease
ContraindicatedALOJA M TABLET is not recommended for use if you recently had a heart attack or have severe circulatory problems, including shock. Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedALOJA M TABLET is not recommended for children and adolescents under 18 years due to the lack of data in these patients. Consult your doctor before taking it.
Use In Geriatrics
Use with CautionALOJA M TABLET should be used with caution with elderly patients. Consult your doctor before taking it.
Others
ALOJA M TABLET is not recommended for use if you:
- Have had a serious allergic reaction to any other antidiabetic medicines
- Have uncontrolled diabetes, with lactic acidosis or ketoacidosis (a condition in which ketone bodies accumulate in the blood and which can lead to diabetic pre-coma)
- Have a severe infection or are seriously dehydrated
Before taking ALOJA M TABLET, inform your doctor if you:
- Have type 1 diabetes (your body does not produce insulin)
- Have had a disease of the pancreas
- Are scheduled for major surgery
- Are planned for an x-ray or scan
Interactions
A. Drug-drug interactions:
- Other antidiabetics (Ex. insulin, glipizide, tolbutamide, glibenclamide, and rosiglitazone)
- Corticosteroids (Ex. hydrocortisone and prednisolone)
- H2-receptor antagonist (Ex. cimetidine)
- Bronchodilators (Ex. salbutamol, levosalbutamol)
- Diuretics (Ex. furosemide)
- NSAIDs (such as ibuprofen and celecoxib)
- Antihypertensives (Ex. enalapril, losartan)
- Medicines containing alcohol
Overdosage:
If you or anyone else accidentally took more ALOJA M TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Alogliptin and Metformin |
| Pharmacological Category | : | DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors), biguanides |
| Therapeutic Indication | : | Type II Diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep ALOJA M TABLET out of the sight and reach of children
- Store ALOJA M TABLET below 30°C
FAQs About ALOJA M TABLET
Q: What is ALOJA M TABLET used for?
A: ALOJA M TABLET is used to manage diabetes mellitus when it cannot be adequately controlled by diet, exercise, and other anti-diabetic medicines. Consult your doctor before taking it.
Q: What are the side effects of taking ALOJA M TABLET?
A: The most common side effects of taking ALOJA M TABLET are stomach pain, diarrhea, loss of appetite, nausea, and vomiting. Consult your doctor if any of the side effects worsen.
Q: What should I avoid while taking ALOJA M TABLET?
A: Avoid excessive consumption of alcohol while taking ALOJA M TABLET, as it may increase the risk of lactic acidosis.
Q: Can ALOJA M TABLET be used with children?
A: ALOJA M TABLET is not recommended for children and adolescents under 18 years due to the lack of data in these patients. Consult your doctor before taking it.
Q: How does ALOJA M TABLET work?
A: ALOJA M TABLET effectively controls blood glucose levels, where alogliptin works by increasing the levels of insulin in the body after a meal and helps decrease the blood glucose levels. Metformin also helps to lower blood glucose by decreasing the amount of sugar made in the liver and helping insulin work more effectively.
Q: What if I forget to take ALOJA M TABLET?
A: If you forget to take a dose of ALOJA M TABLET, take it as soon as you remember it. Do not take a double dose to make up for a forgotten dose.
Q: Is ALOJA M TABLET safe to use during pregnancy?
A: ALOJA M TABLET is not recommended for use if you are pregnant. Inform your doctor if you are pregnant or planning to have a baby before taking this medicine.
Q: How do I take ALOJA M TABLET?
A: Take ALOJA M TABLET with food or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition. Do not stop taking ALOJA M TABLET unless your doctor advises you to stop.
Q: Who should not take ALOJA M TABLET?
A: ALOJA M TABLET is not recommended for use if you are allergic to alogliptin or metformin, have a serious allergic reaction to any other antidiabetic medicines, have uncontrolled diabetes, have lactic acidosis or ketoacidosis, have a severe infection, are seriously dehydrated, or have severe breathing difficulties, severely reduced kidney function, liver disease, or if you recently had a heart attack or have severe circulatory problems, including shock. Consult your doctor before taking it.
Q: Can I take other medicines along with ALOJA M TABLET?
A: Before taking ALOJA M TABLET, inform your doctor if you are taking prescription, non-prescription, or herbal medicines.
References
1. KD. Tripathi. Insulin, Oral Antidiabetic Drugs and Glucagon. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page –298, 299.
2. Futoshi Ebara, Masayuki Domichi, Akiko Suganuma, and Naoki Sakane. Comparison of Metformin and Alogliptin Fixed-Dose Tablets Once a Morning Versus Once an Evening Using Continuous Glucose Monitoring (AMPM Study): An Open-Label Randomized Cross-Over Trial. Journal of endocrinology and metabolism. February 2021. [Accessed on 13th June 2024]. https://www.jofem.org/index.php/jofem/article/view/720/284284505
3. Takeda Ireland Limited. Electronic Medicines Compendium (EMC) [Revised in January 2022] [Accessed on 13th June 2024]. https://www.medicines.org.uk/emc/files/pil.5234.pdf
4. Drug bank. Alogliptin. [Accessed on 13th June 2024]. https://go.drugbank.com/drugs/DB06203
5. Drug bank. Metformin. [Accessed on 13th June 2024]. https://go.drugbank.com/drugs/DB00331
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Random Blood Sugar (RBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin – Fasting
- Insulin Postprandial (PP)
- Vital Diabetes Care
- Extended Diabetes Care
- Advance Diabetes Care
- Comprehensive Diabetes Care
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