INTRODUCTION

ALLEGRA 180MG contains Fexofenadine which belongs to the class of medications called second generation antihistamines, especially the class known as histamine receptor antagonists. It works by blocking the action of one of the body's natural chemicals known as histamine. It is used for the relief of symptoms related with seasonal and year-round allergies including sneezing, itchy palate, runny nose, and itchy, tearing, and redness of the eyes. It is also used in adults and adolescents of 12 years and older to relieve the symptoms that occur with long term allergic skin reactions (chronic idiopathic urticaria) such as itching, swelling and rashes.

ALLEGRA 180MG may be taken with or without food. It should not be taken with fruit juice. Avoid prolonged use of this medication, unless advised by your doctor. Do not stop taking this medication without consulting your doctor. Do not take this medicine within 2 hours of taking an antacid. Before taking this medicine tell your doctor if you have liver, kidney, heart problems and pregnant or breastfeeding. The common side effects are headache, drowsiness and nausea.

USES OF ALLEGRA 180MG

• Relieves symptoms associated with year-round and seasonal allergies, including sneezing, runny nose, itchy, watery, red eyes and itchy nose/palate/throat

HOW ALLEGRA 180MG WORKS

ALLEGRA 180MG blocks a natural substance, histamine that your body makes during an allergic reaction. Fexofenadine is a selectively peripheral H1-blocker. Blockage prevents the activation of the H1 receptors by histamine, preventing the symptoms associated with allergies from occurring.

DIRECTIONS FOR USE

Always take this medicine exactly as your doctor has directed by you. Check with your doctor or if you are not sure. Do not use for a long period of time unless instructed by a doctor. Take your medicine with water before a meal. This medicine starts to relieve your symptoms within 1 hour and lasts for 24 hours.

SIDE EFFECTS OF ALLEGRA 180MG

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea) or indigestion:

Stick to simple meals and do not eat rich or spicy foods.

Headache:

Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller.

Drowsiness or dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• Antacids (contains aluminum or magnesium hydroxide)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ALLEGRA 180MG

What is the use of ALLEGRA 180MG?

It is used in adults and adolescents of 12 years and older to relieve the symptoms that occur with long term allergic skin reactions (chronic idiopathic urticaria) such as itching, swelling and rashes.

What is the best time of day to take ALLEGRA 180MG?

Once-daily antihistamines reach their peak efficacy 8 to 12 hours after you take them, so using them at dinnertime or before bed means better control of your daytime symptoms. Consult your doctor for advice.

Is it okay to take antihistamine everyday?

Based on your symptoms, you can take antihistamines: Every day, to help keep daily symptoms under control. Use when you have symptoms. Consult your doctor for advice.

REFERENCES

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2. Kathleen M. Giacomini and Yuichi sugiyama. Membrane transporters and drug response. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 110.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 543-544.

4. David IBernstein, William FSchoenwetter, Robert Anathan, William Storms, Robert Ahlbrandt and Jolene MasonRN. Efficacy and Safety of Fexofenadine Hydrochloride for Treatment of Seasonal Allergic Rhinitis: Annals of Allergy, Asthma & Immunology, Volume 79, Issue 5, Nov 1997; [Accessed Dec 5, 2020] https://www.sciencedirect.com/science/article/abs/pii/S1081120610630414

5. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC); [Revised Aug 2018] [Accessed Dec 5, 2020] https://www.medicines.org.uk/emc/files/pil.3488.pdf

6. Sanofi Consumer Health Inc. [Revised Nov 7, 2019] [Accessed Dec 5, 2020] http://products.sanofi.ca/en/allegra.pdf