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INTRODUCTION
AGIVOG 0.3MG TABLET contains Voglibose which belongs to the group of medicines called Anti-diabetics. It is used in the treatment of type 2 diabetes mellitus along with diet and exercise to improve post-prandial blood glucose levels (when only diet and/or exercise or oral hypoglycemic drugs or insulin preparation in addition to diet and/or exercise does not result in adequate glycemic control).
Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin, or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue and blurred vision.
Along treatment with AGIVOG 0.3MG TABLET follow regular exercise and diet plan as advised by your doctor to achieve better results.
AGIVOG 0.3MG TABLET is not recommended for use in patients having severe ketosis, in a state of diabetic coma or pre-coma, severe infection, before and after an operation or with serious trauma and gastrointestinal obstruction.
AGIVOG 0.3MG TABLET should be used with caution in patients undergoing abdominal laparotomy for gallstone ileus or have roemheld’s syndrome, stenosis, liver, and kidney problems, and in elderly patients.
AGIVOG 0.3MG TABLET is not recommended for use among pregnant, breastfeeding women, children, and adolescents.
The most common side effects of taking AGIVOG 0.3MG TABLET are soft stools or diarrhea, flatulence, bloating, abdominal pain or discomfort, abdominal fullness, and nausea. Contact your doctor if any of the above symptoms worsen.
USES OF AGIVOG 0.3MG TABLET
- Treats type 2 diabetes mellitus along with diet and exercise
HOW AGIVOG 0.3MG TABLET WORKS
AGIVOG 0.3MG TABLET works by inhibiting the intestinal enzymes that are responsible for breaking complex sugars into simple sugars such as glucose. This prevents the level of blood glucose from increasing very high immediately after meals.
DIRECTIONS FOR USE
Take AGIVOG 0.3MG TABLET as advised by your physician. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF AGIVOG 0.3MG TABLET
COMMON
- soft stools or diarrhea
- flatulence
- abdominal pain or discomfort
- nausea
RARE
- headache
- anemia
- signs of low platelet levels (easy bleeding or bruising)
- signs of low white blood cells (repeated infections)
- numbness
- edema of the face
- blurred vision
- hot flushes
- general discomfort
- weakness
- signs of high potassium levels in blood (irregular heartbeat, muscle weakness, chest pain)
- excessive sweating
- hair loss
Stop taking AGIVOG 0.3MG TABLET and contact your physician immediately if you experience any of the following side effects:
- signs of hypersensitivity reactions (severe skin rash with itching)
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. In case of no improvement, consult your doctor.
Flatulence:
Eat smaller and frequent meals. Slowly eat and drink, and exercise regularly. If the symptom does not improve, contact your physician.
Diarrhea:
Drink more fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own without consulting your physician.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician.
WARNING & PRECAUTIONS
PREGNANCY
AGIVOG 0.3MG TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. Consult your doctor before taking it.
BREASTFEEDING
AGIVOG 0.3MG TABLET is generally not recommended for use in breastfeeding women as it may passes through breast milk. Consult your doctor before taking it.
KIDNEY
AGIVOG 0.3MG TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.
LIVER
AGIVOG 0.3MG TABLET should be taken with caution in patients with liver problems. Consult your doctor for advice.
ALLERGY
Do not take AGIVOG 0.3MG TABLET if you are allergic to Voglibose or to any ingredients of this medicine.
OTHERS
AGIVOG 0.3MG TABLET is not recommended for use if you have:
- severe ketosis
- diabetic coma or pre-coma
- severe infection, after and before an operation
- serious trauma
- gastrointestinal obstruction
Before taking AGIVOG 0.3MG TABLET, inform your physician if you:
- undergoing abdominal laparotomy for gallstone ileus
- have roemheld’s syndrome (cluster of cardiovascular symptoms stimulated by gastrointestinal changes)
- have stenosis (condition in which there is an abnormal narrowing in a blood vessel or other tubular organ or structure such as foramina and canals)
Use in pediatrics:
The safety of AGIVOG 0.3MG TABLET in children has not been established (no clinical experience). Consult your physician before taking AGIVOG 0.3MG TABLET.
Use in geriatrics:
AGIVOG 0.3MG TABLET should be used with caution in elderly patients. Consult your physician before taking AGIVOG 0.3MG TABLET.
INTERACTIONS
A. Drug-Drug interactions:
Before taking AGIVOG 0.3MG TABLET, inform your physician if you are taking any of the following medicines:
- other antidiabetic drugs (Ex. glipizide, tolbutamide, insulin) (used to treat diabetes)
- medicines used to treat heart problems (Ex. metoprolol, atenolol)
- medicine used to treat skin infection (Ex. salicylic acid)
- medicines used to treat depression (Ex. phenelzine, selegiline)
- medicine used to treat cholesterol (Ex. fenofibrate)
- epinephrine (medicine used to treat anaphylaxis reactions)
- adrenocorticotrophin (medicine used to treat disorders of the pituitary or adrenal glands like Cushing’s syndrome)
- thyroxine (medicine used to treat thyroid problems)
Overdosage:
If you or anyone else accidentally take too much of AGIVOG 0.3MG TABLET, consult your physician immediately or visit the nearby hospital. The symptoms of overdosage are low blood sugar levels, abdominal discomfort and diarrhea.
SYNOPSIS
| Drug | : | Voglibose |
| Pharmacological Category | : | Alpha Glucosidase inhibitors |
| Therapeutic Indication | : | Type 2 diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep AGIVOG 0.3MG TABLET out of reach of children
- Store at a room temperature
FAQs ABOUT AGIVOG 0.3MG TABLET
Can AGIVOG 0.3MG TABLET cause diarrhea?
Diarrhea is the common side-effect of AGIVOG 0.3MG TABLET. Drink more fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to treat diarrhea without consulting your physician.
Who should not take AGIVOG 0.3MG TABLET?
AGIVOG 0.3MG TABLET is not recommended for use in patients having severe ketosis, in a state of diabetic coma or pre-coma, severe infection, before and after an operation, or with serious trauma and gastrointestinal obstruction.
What if I forget to take a dose of AGIVOG 0.3MG TABLET?
You should take AGIVOG 0.3MG TABLET immediately when you remember. If it is time for your next dose skip missed the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
How to take AGIVOG 0.3MG TABLET?
Take AGIVOG 0.3MG TABLET as advised by your physician. Your physician will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
What are the common side effects of AGIVOG 0.3MG TABLET?
The most common side effects of taking AGIVOG 0.3MG TABLET are soft stools or diarrhea, flatulence, bloating, abdominal pain or discomfort, abdominal fullness, and nausea. Contact your physician if any of the symptoms worsen.
What happens when I take an overdose of AGIVOG 0.3MG TABLET?
If you or anyone else accidentally take too much of AGIVOG 0.3MG TABLET, consult your physician immediately or visit the nearby hospital. The symptoms of overdosage are low blood sugar levels, abdominal discomfort and diarrhea.
REFERENCES
1. Alvin C. Powers and David D’Alessio. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 863-886.
2. KD. Tripathi. Insulin, Oral Hypoglycemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 258-281.
3. Ajay S. Dabhi, Nikita R. Bhatt, and Mohit J. Shah. Voglibose: An Alpha Glucosidase Inhibitor. Journal of Clinical and Diagnostic Research. December 2013 [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919386/
4. Sanjay Kalra, A Panneer Selvam, Amish V Shah, Kudugunti Neelaveni, Navneet Agrawal, Sambit Das, Vinay K Dhandhania, Subodh Jain, Pankaj Kumar Jha and Neha Rava. Prospective Multicenter Observational Study of Voglibose in Type 2 Diabetes-Victory. Journal of US Endocrinology. January 2020 [Accessed on 21st June 2022] https://www.researchgate.net/publication/342024938_Prospective_Multicenter_Observational_Study_of_Voglibose_in_Type_2_Diabetes-VICTORY
5. Cipla Ltd. Prandal MD Tablets (Voglibose). Cilpamed. [Revised in August 2015] [Accessed on 21st June 2022] https://www.ciplamed.com/content/prandial-md-tablets
6. Amigoz life sciences. Voglibose Tablets. [Accessed on 21st June 2022] http://amigozlife.com/voglibose-tablets.html
7. DM Pharma. Voglibose Tablet. Antidiabetic agents. [Accessed on 21st June 2022] http://www.dmpharma.co.in/Voglibose.html
USEFUL DIAGNOSTIC TESTS
- Glucose - Fasting Blood
- Glucose - Postprandial Blood
- Glycosylated Hemoglobin
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 05 Oct 2022 | 11:16 AM(IST)
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