INTRODUCTION

ACNEWAR GEL contains Dapsone which belongs to the group of medicines called Sulfone antibiotics. It is used in the treatment of acne vulgaris (a skin condition that occurs when the hair follicles are blocked with dead skin cells, bacteria and sebum). The most common symptoms of acne vulgaris are pimples, redness, blackhead and white heads.

Before using ACNEWAR GEL, inform your doctor if you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, methemoglobinemia (a type of blood disorder) and if you are using other products including cosmetics or medicines applied to the skin.

ACNEWAR GEL should be used during pregnancy and breast-feeding only if clearly advised by the doctor. Consult your doctor before using the medicine.

This medicine is not recommended for use in children (younger than 12 years of age). ACNEWAR GEL should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before using the medicine.

The most common side effects associated with the use of ACNEWAR GEL are oiliness/ peeling, redness and dryness. Consult your doctor if any of the side effect worsens.

USES OF ACNEWAR GEL

• Treats acne vulgaris

HOW ACNEWAR GEL WORKS

ACNEWAR GEL works as both anti-bacterial and anti-inflammatory agent in the treatment of acne vulgaris. As an antibacterial agent, it works by inhibiting the synthesis of folic acid which is necessary for the growth of bacteria. Thus, stops the multiplication of bacteria. As an anti-inflammatory agent, it decreases inflammation and heals the breakout.    

DIRECTIONS FOR USE

Always apply ACNEWAR GEL as directed by your doctor. It is for topical use only. Apply a thin layer of this medicine to the areas of your skin that have acne. Avoid contact with eyes, mouth and mucous membranes. Rub the medicine gently and completely. Wash your hands after applying ACNEWAR GEL. Your doctor will decide the duration and frequency of this medicine depending upon severity of the condition.

SIDE EFFECTS OF ACNEWAR GEL

HOW TO MANAGE SIDE EFFECTS

Skin redness or itching:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoor. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

Skin dryness:

Drink lot of fluids. Apply moisturizer several times a day after consulting your doctor. Do not take bath for long time (not more than 5-10 minutes) and use warm water for bathing. Choose fabric clothes to wear. Consult your doctor if the symptom does not improve.

Headache:

Use a heating pad or hot compress. Ease pressure on your scalp or head. Try taking rest in a quiet and dark room. Keep yourself hydrated and practice relaxation. Consult your doctor if the symptom does not improve or gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-drug interactions:

Before using ACNEWAR GEL, inform your doctor, if you are taking any of the following medicines:

• trimethoprim/sulfamethoxazole, nitrofurantoin (used in the treatment and prevention of urinary tract)
• topical benzoyl peroxide (used to treat acne)
• sulphonamides such as sulfadiazine, sulfamethizole (used in the treatment of bacterial infections)
• acetaminophen, acetanilide (used to relive pain)
• nitroprusside, nitrates and nitrites such as glyceryl trinitrate (used to treat angina)
• benzocaine (used to relieve pain)
• oral dapsone (used to treat leprosy, dermatitis herpetiformis)
• pamaquine, chloroquine, para-amino salicylic acid, quinine (used to treat and prevent malaria)
• phenacetin (used to treat fever)
• phenobarbital, phenytoin (used in the treatment of fits)

Over dosage:

ACNEWAR GEL is only for topical use, it is not for oral use. If oral ingestion occurs, consult your doctor or visit the nearby hospital immediately.

SYNOPSIS

MORE INFORMATION

• Keep the medicine away from children
• Store at room temperature (15-30°C)

FAQs ABOUT ACNEWAR GEL

What should I tell my doctor before using ACNEWAR GEL?

Before using ACNEWAR GEL inform your doctor if you are using other products including cosmetics or medicines applied to the skin, glucose-6-phosphate dehydrogenase (G6PD) deficiency, history of slate grey or blueish discoloration of skin, mucous membranes, lips and nail beds due to lack of sufficient oxygen in the blood (methemoglobinemia).

How should I use ACNEWAR GEL?

Use ACNEWAR GEL exactly as told by your doctor. ACNEWAR GEL is usually used on your affected skin twice a day, once in the morning and once in the evening. Wash the areas of your skin where you apply the medicine. Gently pat your skin dry with a clean towel. Apply a thin layer of this medicine to the areas of your skin that have acne. A pea sized amount ACNEWAR GEL will usually be enough. Rub the medicine gently and completely.

What are the most common side effects of ACNEWAR GEL?

The most common side effects of ACNEWAR GEL are skin dryness, redness and oiliness/peeling of the skin. Consult your doctor if you experience any of the symptoms get worse.

How does ACNEWAR GEL work?

ACNEWAR GEL works as both anti-bacterial and anti-inflammatory agent in the treatment of acne vulgaris. As an antibacterial agent, it works by inhibiting the synthesis of folic acid which is necessary for the growth of bacteria. Thus, stops the multiplication of bacteria. As an anti-inflammatory agent, it decreases inflammation and heals the breakout.    

Can ACNEWAR GEL be used in pregnant and breast-feeding women?

ACNEWAR GEL should be used during pregnancy and breast-feeding only if advised by the doctor. Consult your doctor for advice before using the medicine if you are pregnant or breast-feeding mother.     

REFERENCES

1. Gottfried Wozel; Christian Blasum. Research gate. 2013. [Accessed on May 7th 2022] https://www.researchgate.net/publication/259206338_Dapsone_in_dermatology_and_beyond/link/02e7e5326cf1216efe000000/download.

2. Bausch Health. Aczone Topical Gel 5% w/w (Dapsone). [Revised in June 2020] [Accessed on May 7th 2022] https://pdf.hres.ca/dpd_pm/00057223.PDF

3. Taro pharmaceuticals lnc. NIH National Library of Medicine; National centre for biotechnology information. Dailymed. [Revised in July 2018] [Accessed on May 7th 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=97e6444c-1496-4508-9434-8a2a93225e17

4. QLT. U.S. Food and Drug administration. Dapsone. [Revised in May 2016] [Accessed on May 7th 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021794lbl.pdf

5. Cipla Ltd. Acnedap Gel (Dapsone). Ciplamed. [Revised in April 2018] [Accessed on May 7th 2022] https://www.ciplamed.com/content/acnedap-gel

USEFUL DIAGNOSTIC TESTS

• Swab or scrapping of a lesion or pustule