OXERUTE CD(L)

Introduction About OXERUTE CD(L)

OXERUTE CD(L) is a combination of Calcium dobesilate and Troxerutin which belongs to the group of medicines called Vasoprotective agents and Flavonoids respectively. It is used to manage bleeding piles and post piles surgery. It is a double power venotonic.

Hemorrhoids (piles) are swollen veins in anus and lower rectum, similar to varicose veins. It can develop inside the rectum (internal hemorrhoids) or under the skin around the anus (external hemorrhoids). Make sure to avoid spicy, oily foods and take plenty of fibers to aid in digestion and ensure speedy recovery. Before taking OXERUTE CD(L) inform your doctor if you have kidney problems.

Inform your doctor if you are pregnant or breastfeeding before taking OXERUTE CD(L). Safety and effectiveness of OXERUTE CD(L) in children has not been established yet, consult your doctor before taking it. The most common side effects of taking OXERUTE CD(L) are flushing, headache, vertigo. Consult your doctor if symptoms do not reduce.

Uses Of OXERUTE CD(L)

It is used to manage:

• bleeding piles
• post piles surgery

How OXERUTE CD(L) Works

OXERUTE CD(L) is a combination of Calcium dobesilate and Troxerutin. Calcium dobesilate works on the walls of the small blood vessels and reduces their leakage and fragility. It also improves blood flow by decreasing viscosity, thickness of the blood, thereby relieving inflammation (redness and swelling) in hemorrhoids and promotes healing. Troxerutin strengthens the blood vessels in the affected area.

How to use OXERUTE CD(L)

Take OXERUTE CD(L) as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.

Side Effects Of OXERUTE CD(L)

How To Manage Side Effects

Headache

Avoid bright lights, take enough rest and drink more water. Consult your doctor if symptoms do not show improvement.

Warning & Precautions

Pregnancy

Consult your doctor

There is limited information available on the use of OXERUTE CD(L), hence inform your doctor if you are pregnant before taking OXERUTE CD(L).

Breastfeeding

Consult your doctor

There is limited information available on the use of OXERUTE CD(L), hence inform your doctor if you are breastfeeding before taking OXERUTE CD(L).

Kidney

Use with Caution

OXERUTE CD(L) should be used with caution in patients with kidney disease. Dose will be adjusted by your doctor. Consult your doctor before taking.

Allergy

Contraindicated

Do not take OXERUTE CD(L) if you are allergic to Calcium dobesilate or Troxerutin or any other ingredients of this medicine.

Use In Pediatrics

Consult your doctor

Safety and effectiveness of OXERUTE CD(L) in children is not established yet. Consult your doctor before taking.

Interactions

A. Drug-Drug interactions:

Before taking OXERUTE CD(L), inform your doctor if you are taking any prescription, non-prescription and herbal supplements.

Overdosage:

If you or anyone else accidentally takes too much of OXERUTE CD(L), consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep OXERUTE CD(L) out of reach of children
• Store at room temperature

FAQs About OXERUTE CD(L)

Q: What is OXERUTE CD(L) used for?

A: OXERUTE CD(L) is used to manage bleeding piles and post piles surgery. It is a double power venotonic.

Q: How does OXERUTE CD(L) work?

A: OXERUTE CD(L) is a combination of Calcium dobesilate and Troxerutin. Calcium dobesilate works on the walls of the small blood vessels and reduces their leakage and fragility. It also improves blood flow by decreasing viscosity, thickness of the blood, thereby relieving inflammation (redness and swelling) in hemorrhoids and promotes healing. Troxerutin strengthens the blood vessels in the affected area.

Q: Can OXERUTE CD(L) be used in pregnant women?

A: There is limited information available on the use of OXERUTE CD(L), hence inform your doctor if you are pregnant before taking OXERUTE CD(L).

Q: Can OXERUTE CD(L) be used in patients with kidney problems?

A: OXERUTE CD(L) should be used with caution in patients with kidney disease. Dose will be adjusted by your doctor depending on the disease condition. Consult your doctor before taking.

References

1. Goodman & Gilman. Treatment of Disorders of Bowel Motility and Water Flux; Anti- Emetics. The pharmacological basics of therapeutics. Twelfth Edition. 2011. Page –1333.

2. Jie Liu, Shulin Lia, Dong Sun. Calcium Dobesilate and Micro-vascular diseases. [Accessed on 18th July 2022] https://www.sciencedirect.com/science/article/abs/pii/S0024320519301134

3. Niranjan A Panat, Beena G Singh, Dharmendra K Maurya, Santosh K Sandur, Saroj S Ghaskadbi. Troxerutin, a natural flavonoid bind to DNA minor groove and enhances cancer cell killing in response to radiation. [Accessed on 18th July 2022] https://pubmed.ncbi.nlm.nih.gov/27016192/

4. Om pharma. Calcium dobesilate. [Accessed on 18th July 2022] https://www.e-lactancia.org/media/papers/Dobesilate-DS-OMPharma2018.pdf

5. Pubchem. Troxerutin. [Accessed on 18th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Troxerutin

6. Pubchem. Calcium dobesilate. [Accessed on 18th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/calcium_dobesilate

7. Troxerutin. NIH. [Accessed on 18th July 2022] https://drugs.ncats.io/drug/7Y4N11PXO8

8. CIMS. Troxerutin. [Accessed on 18th July 2022] https://www.mims.com/india/drug/info/troxerutin?type=full&mtype=generic

9. Hasco-lek. Calcium dobesilate. [Revised in April 2020] [Accessed on 18th July 2022] http://www.hasco-lek.pl/en/products/products/dobenox-250-mg-coated-tablets?start=72

10. Troxerutin. Sciencedirect. [Accessed on 18th July 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/troxerutin

11. Calcium dobesilate +Troxerutin. Hopkins medicine. [Accessed on 18th July 2022] https://www.hopkinsmedicine.org/health/conditions-and-diseases/chronic-venous-insufficiency

12. Calcium dobesilate+Troxerutin. Mayoclinic. [Revised on May 2021] [Accessed on 18th July 2022] https://www.mayoclinic.org/diseases-conditions/hemorrhoids/symptoms-causes/syc-20360268

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Shruthi Raikar - BDS

Last updated on 22 Mar 2023 | 04:03 PM(IST)