PRACTIN TABLET 10'S (N)

INTRODUCTION ABOUT PRACTIN

PRACTIN contains cyproheptadine, which belongs to the group of medicines called Antihistamines. It is used in the management of allergic conditions such as seasonal and perineal rhinitis, hay fever, skin rashes, and allergic conjunctivitis.

Perennial rhinitis refers to specific allergens that cause an allergic reaction year-round, such as pet hair or dander, food allergies, or medicines. Whereas, seasonal allergies typically occur with weather changes or environmental changes such as pollen, insects, moisture, dryness, fungi, mold, etc.

PRACTIN is not recommended for debilitated patients above 65 years of age with renal, hepatic, or cardiac conditions. PRACTIN must be used in pregnant women only if recommended by your doctor. It is not recommended for use in breastfeeding mothers.

The medicine should be used with caution in adolescents and children (above 7 years of age) only. Consult your doctor before taking it. The most common side effects include dizziness, drowsiness, and high fever. Contact your doctor if any of the symptoms worsen.

USES OF PRACTIN

Manages allergic conditions in children (above 7 years of age) and adults, such as:

• seasonal (occurring during a specific season) and perennial rhinitis (occurring year-round)
• vasomotor rhinitis (reoccurring inflammation of the mucous membrane in the nose)
• allergic conjunctivitis (eye inflammation caused by allergy)
• urticaria (hives) and angioedema (swelling beneath the skin)
• amelioration of allergic reactions to blood or plasma (allergic severe reactions after blood or plasma transfusions)
• cold urticaria (skin reaction to cold)
• dermatographia (a condition causing raised red lines after a scratch)
• It is also used as adjuvant therapy for serious allergic reactions

HOW PRACTIN WORKS

PRACTIN manages allergic reactions by binding with certain receptors and blocking them from binding with histamine in the body. Histamine is a mediator found in our body that is responsible for causing allergic symptoms (such as inflammation, itching and irritation etc.) as a response to allergic conditions. Thereby, providing us relief from the allergic condition.

DIRECTIONS FOR USE

Take PRACTIN as advised by your physician. It can be taken independent of meals. Swallow the medicine with a glass of water. Do not crush or chew PRACTIN. Your doctor will decide the correct dose, frequency and duration of the management for you depending upon your age, body weight, and disease condition.

SIDE EFFECTS OF PRACTIN

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve.

Constipation:

Eat plenty of fiber-rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly.

WARNING & PRECAUTIONS

PREGNANCY

PRACTIN must be used in pregnant women only if recommended by your doctor. Consult your doctor before taking PRACTIN.

BREASTFEEDING

PRACTIN is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking PRACTIN.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy or feel that your mental alertness or motor coordination is affected after taking PRACTIN.

ALCOHOL

Avoid consumption of alcohol while taking PRACTIN because it causes an additive effect, making you feel dizzy or drowsy.

KIDNEY

PRACTIN should be taken with caution in patients with severe kidney disease. Consult your doctor before taking PRACTIN.

LIVER

PRACTIN should be taken with caution in patients with severe liver disease. Consult your doctor before taking PRACTIN.

ALLERGY

Do not take PRACTIN if you are allergic to cyproheptadine.

LUNGS

PRACTIN should be taken with caution in patients with a history of bronchial asthma. Consult your doctor before taking PRACTIN.

HEART DISEASE

PRACTIN should be taken with caution in patients with cardiovascular disease and hypertension. Consult your doctor before taking PRACTIN.

INTERACTIONS

A. Drug-Drug interactions:

Before taking PRACTIN, inform your doctor if you are taking any of the following medicine

• medicines used to manage depression such as MAO inhibitors (Mono Amine Oxidase inhibitors) (Ex. selegiline)
• other depressants such as CNS depressants (Ex. barbiturates)
• medicine used as sedatives (Ex. diazepam)
• medicines used as hypnotics (Ex. zopiclone)
• medicines used as tranquillizers to manage mental disturbances (Ex. alprazolam)
• anti-anxiety medicine used to manage anxiety (Ex. clonazepam)

Overdosage:

If you or anyone else have accidentally taken too much of PRACTIN, consult your doctor immediately or visit the nearby hospital. In children, it could cause diminishing mental alertness and sometimes cause excitation, whereas in adults, it could cause symptoms such as dry mouth, fixed dilated pupils, flushing and gastrointestinal symptoms such as diarrhoea, vomiting, etc.

SYNOPSIS

MORE INFORMATION

• Keep out of reach from children
• Store at room temperature

FAQs ABOUT PRACTIN

Does PRACTIN make you gain weight?

Yes, though PRACTIN is an antihistamine, it is also used to stimulate the appetite and promote weight gain. On the contrary, it is a negative effect as it can cause obesity due to the rapid weight gain in the person after taking it. Consult your doctor before taking PRACTIN.

Can PRACTIN be used for insect bites?

Yes, PRACTIN can be used to manage allergic reactions caused by insect bites. Inflammation and irritation caused by the insect bite are restricted by PRACTIN causing relief from symptoms. Consult a doctor before taking it.

Can I take PRACTIN with anti-depressants?

No, PRACTIN is not recommended for use with an anti-depressant (Ex. Sertraline, citalopram), as co-administration of these two medicines may increase the risk of having an additive effect on the medicine and can cause unnecessary complications. Consult a doctor for advice before taking PRACTIN.

Does PRACTIN make you feel sleepy?

Yes, PRACTIN has a sedative property that may make you feel sleepy or drowsy. Avoid driving or using heavy machinery while taking PRACTIN.

How long should I take PRACTIN?

PRACTIN should be taken for as long as your doctor has prescribed it. However, consult your doctor immediately if you experience any of the side effects and they persist or worsen with rash, fever, or weight gain.

When should I avoid it before taking PRACTIN?

Avoid taking PRACTIN if you are suffering from bronchial asthma, glaucoma, enlarged prostate, urinary problems or stomach ulcers. Inform your doctor about your medical condition before starting PRACTIN therapy.

Does PRACTIN cause dry mouth?

Yes, PRACTIN can cause dry mouth. If you experience mouth dryness or feel excessively thirsty, increase your fluid intake, rinse your mouth with water frequently, and apply lip balm if you feel your lips are dry or chapped out.

REFERENCES

1. K D Tripathi. Antiemetics. Essentials of Medical Pharmacology. 8th edition. Page - 174.

2. Bertrand, Valérie et al. Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. National Library of Medicine. (PMC). [Accessed on 18th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525494/

3. Najib, Khadijehsadat et al. Beneficial effect of cyproheptadine on body mass index in undernourished children: a randomized controlled trial. National Library of Medicine. (PMC). [Accessed on 18th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442838/

4. Emcure Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Accessed on 18th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/087056s045lbl.pdf

5. Merck Sharp & Dohme. Ltd [Revised in October 2007] [Accessed on 18th June 2022] https://apps.medicines.org.au/files/mkpperia.pdf

6. Ronak Exim Private Limited. [Accessed on 18th June 2022] https://fdaghana.gov.gh/img/smpc/Happyrona%204mg%20Tablets%20(Cyproheptadine).pd

7. Marlex Pharmaceuticals Inc. [Revised in October 2021] [Accessed on 18th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c382a921-f801-4b63-885a-00e71d3c19c7

8. Ciplamed. [Revised in November 2013] [Accessed on 18th June 2022] https://www.ciplamed.com/content/ciplactin-tablets

9. Cadila Healthcare Ltd. Safety Data Sheet. [Accessed on 18th June 2022] https://imgcdn.mckesson.com/CumulusWeb/Click_and_learn/SDS_9ZYDUS_CYPROHEPTADINE_HCL_TAB_4MG_100_BT.pdf

AUTHOR DETAILS

Written By Dr. Dhivakaran R - BDS

Last updated on 01 Oct 2022 | 03:49 PM(IST)