NURODAY 1.5MG(L)

Introduction About NURODAY 1.5MG(L)

NURODAY 1.5MG(L) contains Mecobalamin which belongs to the group of medicines called Vitamins. NURODAY 1.5MG(L) is used to manage peripheral neuropathies (peripheral nerve damage that affects hands, feet and arms) and megaloblastic anaemia (blood disorder that occurs due to abnormal production of red blood cells) caused by vitamin B12 deficiency in affected individuals.

NURODAY 1.5MG(L) is not recommended for use in patients allergic to mecobalamin and/or other B12 containing medicines. It also not recommended for use in patients with Leber’s disease (inherited form of vision loss).

Before taking NURODAY 1.5MG(L), inform your doctor if you are in an occupation of handling mercury and/or have kidney problems (such as renal failure) and liver problems (such as hepatic impairment).

NURODAY 1.5MG(L) is not recommended for use during pregnancy and in breastfeeding women. It should be used with caution in children and adolescents (aged 6 months to 18 years). It is also used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.

The most common side effects of taking NURODAY 1.5MG(L) are weakness, headache, back pain, muscle pain, indigestion, nausea and/or vomiting. Consult your doctor if any of these side effects worsens.

Uses Of NURODAY 1.5MG(L)

• Manage peripheral neuropathies.
• Manage megaloblastic anaemia (caused by vitamin B12 deficiency) in affected individuals.

How NURODAY 1.5MG(L) Works

NURODAY 1.5MG(L) works by aiding in the synthesis of myelin (lipid rich material that covers nerve fibres) which helps in protecting the nerve fibres and thereby providing relief from painful diabetic neuropathy in affected individuals.   It also promotes nucleic acid synthesis in the bone marrow which helps in the maturation and division of erythroblasts thus managing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.

How to use NURODAY 1.5MG(L)

Tablet:

Take NURODAY 1.5MG(L) as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Oral Disintegrating Tablet:

Take NURODAY 1.5MG(L) as advised by your physician. Place NURODAY 1.5MG(L) inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of NURODAY 1.5MG(L)

How To Manage Side Effects

Headache:

If NURODAY 1.5MG(L) causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking NURODAY 1.5MG(L). If it lasts more than a week or severe, inform your doctor.

Indigestion:

Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea or alcohol and lose weight if you are obese.  Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.

Nausea and vomiting:

Take NURODAY 1.5MG(L) with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Talk with your doctor if the condition worsens.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Warning & Precautions

Pregnancy

NURODAY 1.5MG(L) is not recommended for use in pregnant women. Consult your doctor before taking NURODAY 1.5MG(L).

Breastfeeding

NURODAY 1.5MG(L) is not recommended for use in breastfeeding women. Consult your doctor before taking NURODAY 1.5MG(L).

Kidney

NURODAY 1.5MG(L) should be used with caution in patients with kidney problems such as renal failure. Consult your doctor before taking the medicine.

Liver

NURODAY 1.5MG(L) should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before taking the medicine.

Allergy

Do not take NURODAY 1.5MG(L) if you are allergic to mecobalamin, other B12 containing medicines and/or any other ingredients of this medicine.

Interactions

A. Drug - Drug interactions:

Before taking NURODAY 1.5MG(L), inform your doctor if you are taking any of the following medicine:

• neomycin (used to prevent/manage bacterial skin infections)
• amino salicylic acid (used to manage tuberculosis)
• histamine H2-antagonists (used to manage recurrence of duodenal ulcers) Ex. ranitidine, famotidine 
• colchicine (used in the management of gout)
• oral contraceptives (used to manage pregnancy) Ex. ethinyl estradiol and norethindrone
• chloramphenicol (used to manage bacterial infections)
• omeprazole (used to manage gastric & duodenal ulcers, erosive esophagitis and gastroesophageal reflux disease).

Overdosage:

If you or anyone else accidentally take too much of NURODAY 1.5MG(L), consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

Synopsis

More Information

• Keep NURODAY 1.5MG(L) out of reach of children
• Store NURODAY 1.5MG(L) below 30°C.

FAQs About NURODAY 1.5MG(L)

What is NURODAY 1.5MG(L) used for?

NURODAY 1.5MG(L) is used to manage peripheral neuropathies (peripheral nerve damage that affects hands, feet and arms) and megaloblastic anaemia (blood disorder that occurs due to abnormal production of red blood cells) which occurs due to deficiency of vitamin B12 in affected individuals.

How NURODAY 1.5MG(L) be taken?

Tablet:

Take NURODAY 1.5MG(L) as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Oral Disintegrating Tablet:

Take NURODAY 1.5MG(L) as advised by your physician. Place NURODAY 1.5MG(L) inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

What are the side effects of NURODAY 1.5MG(L)?

The most common side effects of taking NURODAY 1.5MG(L) are weakness, headache, back pain, muscle pain, indigestion, nausea and/or vomiting. Consult your doctor if any of these side effects worsens.

How NURODAY 1.5MG(L) works?

NURODAY 1.5MG(L) works by aiding in the synthesis of myelin (lipid rich material that covers nerve fibres) which helps in protecting the nerve fibres and thereby providing relief from painful diabetic neuropathy in affected individuals.   It also promotes nucleic acid synthesis in the bone marrow which helps in the maturation and division of erythroblasts thus managing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.

Can NURODAY 1.5MG(L) be used in pregnant and breastfeeding women?

No, NURODAY 1.5MG(L) is not recommended for use in pregnant and breastfeeding women since it may cause some undesirable effects to the foetus and breastfed baby. Consul your doctor before taking NURODAY 1.5MG(L).

References

1. KD. Tripathi. Drugs affecting blood and blood formation, Vitamins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 606.

2. Advait Vasavada; Devang Sanghavi. Cyanocobalamin.  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. September 2022. [Accessed on 4th November 2022] https://www.ncbi.nlm.nih.gov/books/NBK555964/

3. A S M Al Amin; Vikas Gupta. Vitamin B12 (Cobalamin).  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed on 4th November 2022] https://www.ncbi.nlm.nih.gov/books/NBK559132/

4. Rabia G Sezer, Abdulkadir Bozaykut, Handan A Akoglu, Gül N Özdemir. The Efficacy of Oral Vitamin B12 Replacement for Nutritional Vitamin B12 Deficiency.  NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov.  March 2018. [Accessed on 4th November 2022] https://pubmed.ncbi.nlm.nih.gov/29189512/

5. Emmanuel Andrès, Thomas Vogel, Laure Federici, Jacques Zimmer,  Ecaterina Ciobanu and Georges Kaltenbach. Cobalamin Deficiency in Elderly Patients: A Personal View. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. May 2008.  [Accessed on 4th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672039

6. Getz Pharma (Pvt) Ltd. Nervon. [Accessed on 4th November 2022] https://getzpharma.com/wp-content/uploads/2016/08/Nervon-Range-Leaflet-Export-GA.pdf

7. Mova Pharmaceutical Pvt Ltd. MOVACOBAL MD 3. [Accessed on 4th November 2022] http://movapharma.com/cod-division.php

8. Micro Labs Ltd. Meconerv Tablet. [Accessed on 4th November 2022] https://www.microlabsltd.com/elibrary/node/1908

Useful Diagnostic Tests

• Nerve conduction test
• Complete blood count

Author Details

Written By Dr. K .AZEEM HUSSAIN - B.D.S

Reviewed For Accuracy By Dr. Shruthi Raikar - BDS

Last updated on 09 Nov 2022 | 02:13 PM(IST)