CANESTEN VAG contains clotrimazole which belongs to the group of medicines called azole antifungal agents. It is used to treat fungal skin infections such as athlete’s foot, ringworm, fungal nappy rash (in babies) and fungal sweat rash. It can also be used to treat irritation of the vulva (external thrush) or irritation at the tip of the penis (penile thrush). External thrush is a common fungal infection caused by the aggravation of the fungi, that usually lives harmlessly in the vagina or vulva.
Penile thrush often occurs by having sexual intercourse with the partner having vaginal thrush and is characterized by redness and soreness of the penis with a white non-smelling penile discharge. Topically applied clotrimazole acts by blocking the biosynthesis of fungal ergosterol which leads to the disruption of fungal cell membrane and inhibition of fungal growth. This medicine is for external use only. Do not swallow it. Your doctor will decide the duration of the therapy depending upon the type of the infection.
Along with the treatment, try to keep the infected area clean by washing it daily. Always wear cotton underwear and loose-fitting clothes and change your sanitary protection regularly. Try not to share your towels and bathmats with other people, as it could prevent the spread of infection. The most common side effects of CANESTEN VAG are application site redness, swelling, itching, burning or peeling. Contact your doctor if any of the symptom bothers you. If you are pregnant or think you may be pregnant or breastfeeding, consult your doctor for advice before using. Your doctor will decide whether you should use this medicine or not.
Clotrimazole exerts its antifungal activity by inhibiting the biosynthesis of ergosterol, an essential constituent of fungal cell membrane which helps to keep the fungal cell intact and directly promotes its growth. Inhibition of ergosterol biosynthesis damages the fungal cell integrity and leads to the inhibition of fungal growth.
Wash the infected area thoroughly and pat it dry. Apply a thin layer of this medicine evenly to the affected areas two or three times daily or as directed by your physician and gently rub it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and type or severity of the infection.
It is for external use only. Do not swallow the medicine. Avoid contact with eyes or mouth, if happens rinse it thoroughly with water. Continue to apply this medicine, as long as your doctor tells you to do so, to obtain better results.
Application site reactions:
Avoid hot showers because hot water can irritate the skin. Do not use perfumed soaps or vaginal deodorants. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Wear cotton underwear and loose-fitting clothes and change your sanitary protection regularly. Regularly use moisturizers to soothe and hydrate the affected area. If the symptoms still persist, contact your doctor.
CANESTEN VAG should be used with caution in pregnant women. Consult your doctor before using.
CANESTEN VAG should be used with caution in breastfeeding women. Consult your doctor before using.
Do not apply this medicine if you or your baby are allergic to clotrimazole or any other vaginal antifungal products.
CANESTEN VAG is not recommended for use in patients having nail or scalp infections. Consult your doctor before application.
Tell your doctor about all the medicines you use, including non-prescription and prescription medicines and herbal supplements.
| Drug | : | Clotrimazole |
| Pharmacological Category | : | Imidazole derivative, Antifungal agent |
| Therapeutic Indication | : | Fungal skin infection, Thrush |
| Dosage Forms | : | Vaginal tablet, Cream, Gel, Topical solution, Lotion, Dusting powder, Throat lozenges, Ear drops, Mouth paint, Soap |
Can CANESTEN VAG be used in babies?
Yes. This medicine can be used in babies to treat fungal nappy rash. However, consult your doctor before application.
Can I use CANESTEN VAG when I’m pregnant?
This medicine must be used with great caution in pregnant women. Consult your doctor before taking. Your doctor will decide whether you should use this medicine or not.
Can CANESTEN VAG be used to treat pimples?
No. This medicine is only used to treat fungal skin infections such as athlete’s foot, ringworm, fungal nappy rash, fungal sweat rash and thrush.
1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 792.
2. John E. Bennett. Antifungal agents. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1587.
3. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 895-897.
4. Ache Laboratorios Farmaceuticos S.A. Efficacy and Safety of the Association of Clotrimazole and Metronidazole in the Treatment of Vaginal Discharge From Different Etiologies. (Frauen). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on March 2016] [Accessed 19th January 2021] https://clinicaltrials.gov/ct2/show/NCT02713139
5. E S Mahgoub. Clinical trial with clotrimazole cream (Bay b 5097) in dermatophytosis and onychomycosis. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 1975. [Accessed 19th January 2021] https://pubmed.ncbi.nlm.nih.gov/128698/
6. Mylan UK Healthcare Limited. Electronic Medicines Compendium (EMC); [Revised on July 2020] [Accessed 19th January 2021] https://www.medicines.org.uk/emc/files/pil.2598.pdf
7. GP Grenzach Produktions GmbH. Electronic Medicines Compendium (EMC); [Revised on January 2019] [Accessed 19th January 2021] https://www.medicines.org.uk/emc/files/pil.1282.pdf
8. Palsons Derma Pvt Ltd. KANSEL-DS Gel, lotion. Palsonsderma.com. [Accessed 19th January 2021] https://www.palsonsderma.com/kansel-ds-gel-ds-lotion
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