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The combination of Metformin and Sitagliptin is used to control blood sugar levels in patients with type II diabetes mellitus along with proper diet and exercise.
Metformin: Antidiabetic agents (Biguanides)
Sitagliptin: Antidiabetic agents (Dipeptidyl peptidase 4 (DPP-4) inhibitor)
Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absorption in the body.
Sitagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, it controls blood sugar levels and improve glycemic control in patients with type II diabetes.
Consult your doctor: