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Introduction About SELOKEN XL 50MG TABLET

SELOKEN XL 50MG TABLET is used in the management of high blood pressure, angina pectoris (chest pain), heart failure, arrhythmias or palpitations, heart attacks and migraine headaches. It contains Metoprolol which is a beta-blocker that works by controlling heart functions and reduces strain on the heart.

Take SELOKEN XL 50MG TABLET only under medical supervision. It is usually taken with or immediately after meals. Do not stop taking this medicine without consulting your doctor as a precaution.

Avoid alcohol consumption while taking this medicine as it lowers blood pressure. It is not recommended for use in patients with asthma, COPD, severe bradycardia, second or third-degree heart block, cardiogenic shock, cardiac failure, sick sinus syndrome (unless a permanent pacemaker is present) and unmanaged pheochromocytoma.

Before taking this medicine, inform your doctor if you have diabetes, stroke, liver or kidney disease or if you are pregnant or breastfeeding as a precaution.

Low blood pressure, tiredness, dizziness, headache, cold hands and feet are some of the common side effects associated with the use metoprolol. These side effects are usually manageable. However, consult your doctor if they trouble you.

Uses Of SELOKEN XL 50MG TABLET

High blood pressure
Angina pectoris (chest pain)
Arrhythmias or palpitations
Heart attack and heart failure
Migraine

How SELOKEN XL 50MG TABLET Works

In hypertension, SELOKEN XL 50MG TABLET works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons, and suppressing renin activity (normally responsible for the increase in blood pressure). Together, these actions lower blood pressure effectively.

In angina pectoris, SELOKEN XL 50MG TABLET works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.

In heart failure, SELOKEN XL 50MG TABLET slows down the heart rate and makes it easier for the heart to pump blood around the body.

How to use SELOKEN XL 50MG TABLET

Take this medicine exactly as prescribed by your doctor. The dose depends on your condition (like high blood pressure or heart-related issues) and response to the treatment
It is usually recommended to take metoprolol with or immediately after a meal to enhance absorption and reduce side effects like dizziness
Swallow the medicine with a glass of water. Do not crush or chew the medicine
Take the tablet at the same time each day, as this helps maintain consistent levels of the medication in your body
If you miss a dose, take it as soon as you remember, but if it's almost time for your next dose, skip the missed one. Do not double the dose
Do not stop taking metoprolol abruptly, as it can worsen your condition. Always follow your doctor’s advice when discontinuing
Always consult your healthcare provider for personalized instructions

Side Effects Of SELOKEN XL 50MG TABLET

Common side effects of SELOKEN XL 50MG TABLET:

feeling faint on standing because of low blood pressure
tiredness, drowsiness
cold hands and feet
palpitations
dizziness, headache
diarrhoea, constipation, abdominal pain
fluid retention (swelling)
pins and needles
muscle cramps
weight gain, increased sweating
depression, reduced concentration
difficulty in sleeping
shortness of breath
skin rash

Stop taking SELOKEN XL 50MG TABLET and contact your physician immediately if you experience any of the following side effects:

symptoms of an allergic reaction such as skin rash, itching, flushing, swelling of the face, lips, tongue or throat, difficulty in breathing or swallowing

Warning & Precautions

Pregnancy

Contraindicated

SELOKEN XL 50MG TABLET is not recommended for use in pregnant women.

Breastfeeding

Contraindicated

It is not recommended for use in breastfeeding women, as metoprolol may pass through the breast milk.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy and tired after taking this medicine.

Alcohol

Consult your doctor

Avoid alcohol consumption while taking this medicine as it will make you feel dizzier.

Kidney

Use with Caution

SELOKEN XL 50MG TABLET should be used with caution in patients with kidney diseases such as abnormal function.

Liver

Use with Caution

It should be used with caution in patients with liver diseases.

Allergy

Contraindicated

Do not take SELOKEN XL 50MG TABLET if you are allergic to Metoprolol or any other ingredients in this medicine.

Lungs

Contraindicated

SELOKEN XL 50MG TABLET is not recommended for use in patients with bronchospastic diseases like asthma or COPD.

Heart Disease

Consult your doctor

SELOKEN XL 50MG TABLET is not recommended for use in patients with severe bradycardia, low blood pressure, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, or sick sinus syndrome (unless a permanent pacemaker is present) and should be used with caution in patients with 1st-degree heart block, myocardial infarction, angina pectoris, heart failure, diseases of the heart valve, or enlarged heart muscle.

Use In Pediatrics

Contraindicated

There is limited data on the use of metoprolol in children and adolescents. Therefore, the use of metoprolol is not recommended.

Use In Geriatrics

Use with Caution

This medicine should be used with caution in elderly patients aged 65 years or above.

Others

SELOKEN XL 50MG TABLET is not recommended for use if you have:

severe peripheral arterial disease
metabolic acidosis
unmanaged phaeochromocytoma

Before taking this medicine, inform your doctor if you have:

major surgery or anaesthesia
stroke
diabetes or low blood sugar
hyperthyroidism
peripheral vascular disease
psoriasis

Interactions

A. Drug-Drug interactions:

Before taking this medicine inform your doctor if you are taking any of the following medicine:

other antihypertensive agents (such as reserpine, clonidine, hydralazine, alpha methyldopa, guanfacine, diltiazem, and verapamil)
Anti-arrhythmic agents (such as quinidine, amiodarone, propafenone, disopyramide)
Antidepressants
digitalis (a medicine used to manage heart failure)
cimetidine (a medicine used to manage ulcers)
terbinafine (a medicine used to manage fungal infection)
hydroxychloroquine (a medicine used to manage malaria)
Antipsychotics (Ex. chlorpromazine, triflupromazine, chlorprothixene)
diphenhydramine (medicines used to manage allergies)
celecoxib, indomethacin (medicines used to manage pain)
rifampicin (medicines used to manage tuberculosis)
other beta-blockers, Ex. timolol eye drops
adrenaline, noradrenaline (medicines used to manage shock)
Antidiabetic agents (such as glimepiride)
lidocaine (a medicine used to induce numbness)

Overdosage:

If you or anyone else has accidentally taken too much of this medicine, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, bluish discolouration of the skin, severe bradycardia, low blood pressure (fatigue, dizziness), atrioventricular block, heart failure, bronchospasm or shortness of breath.

Synopsis

Drug	:	Metoprolol
Pharmacological Category	:	Beta-blockers
Therapeutic Indication	:	High blood pressure, Angina pectoris, Heart failure
Dosage Forms	:	Tablet, Capsule, Injection

More Information

To know more about this medicine:

FAQs About SELOKEN XL 50MG TABLET

Q: How SELOKEN XL 50MG TABLET work?

A: In hypertension, this medicine works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons and suppressing renin activity (normally responsible for an increase in blood pressure). Together, these actions lower blood pressure effectively.

In angina pectoris, it works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.

In heart failure, it slows down the heart rate and makes it easier for the heart to pump blood around the body.

Q: What is SELOKEN XL 50MG TABLET used for?

A: SELOKEN XL 50MG TABLET is used to manage high blood pressure, angina, heart failure, arrhythmias, and migraines.

Q: Can SELOKEN XL 50MG TABLET cause high blood sugar?

A: Yes. This medicine may raise blood sugar levels and should be used with caution in patients with diabetes or low blood sugar. Consult your doctor for more information.

Q: Can SELOKEN XL 50MG TABLET cause low blood pressure?

A: Sometimes, this medicine may decrease your blood pressure and causes dizziness, headache, sweating, and faintness on standing up which is easy manageable by taking some salty snack. If you experience severe dizziness, unable to sit with plenty of exhaustion, talk to your doctor.

Q: Can I stop taking SELOKEN XL 50MG TABLET if I feel better?

A: Do not stop this medicine suddenly without informing your physician. As it may lead to an exacerbation of angina pectoris (chest pain) or myocardial infarction (heart attack). Contact your doctor before stop taking it.

References

1. K D Tripathi. Cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 523, 545, 564.

2. Bethesda (MD). Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubMed, 2006. [Accessed on 30th June 2022] click here

3. Aralez Pharmaceuticals US Inc. Metoprolol. [Revised in December 2016] [Accessed on 30th June 2022] click here

4. Dr Reddy’s Laboratories Limited. Metoprolol. [Revised in April 2016] [Accessed on 30th June 2022] click here

5. STADA Arzneimittel AG. Metoprolol. [Accessed on 30th June 2022] click here

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Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 20 Nov 2024 | 12:06 PM(IST)